Zobrazeno 1 - 10
of 169
pro vyhledávání: '"Chitoshi Itakura"'
Publikováno v:
Pharmacology Biochemistry and Behavior. 124:250-259
Cav2.1α1 is involved in glutamate release. The kainate-induced intensive firing of neurons via glutamate receptors causes seizure and neuronal damage, especially in the hippocampus. Cav2.1α1 mutation in homozygous rolling Nagoya (rol/rol) mice caus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::caf44fb0a68138bf370d6e806f877398
https://doi.org/10.1016/j.pbb.2014.06.022
https://doi.org/10.1016/j.pbb.2014.06.022
Publikováno v:
Journal of Veterinary Medical Science. 76:1093-1098
Ataxic rolling Nagoya (PROD-rol/rol) mice, which carry a mutation in the α1 subunit of the Cav2.1 channel (Cacna1a) gene, were discovered in 1969. They show white spots on agouti coat and have a mutation in the piebald spotting (s) locus. However, m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d7094bcc252b12962f6f2a883af57703
https://doi.org/10.1292/jvms.14-0096
https://doi.org/10.1292/jvms.14-0096
Publikováno v:
Brain Research. 1515:48-54
Senescence-accelerated mouse prone (SAMP) strains of mice show early onset of senescence, whereas senescence-accelerated mouse resistant (SAMR) strains are resistant to early senescence and serve as controls. Although SAMP6 and SAMP8 are established
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61f9c93bd11a9c9f9159b05847ce1e17
https://doi.org/10.1016/j.brainres.2013.03.053
https://doi.org/10.1016/j.brainres.2013.03.053
Publikováno v:
European Journal of Pharmacology. 645:113-118
Ca(V)2.1 is highly expressed in the nervous system and plays an essential role in the presynaptic modulation of neurotransmitter release machinery. Recently, the antiepileptic drug levetiracetam was reported to inhibit presynaptic Ca(V)2.1 functions,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9edd278586eaf87356890b62504f01fb
https://doi.org/10.1016/j.ejphar.2010.07.029
https://doi.org/10.1016/j.ejphar.2010.07.029
Publikováno v:
Experimental Animals. 59:441-447
Many neuropharmacological agents modulate the activity and conformation of heptahelical G protein-coupled receptors and activate ligand-specific signaling pathways. The hallucinogenic chemical 1-[2,5-dimethoxy-4-iodophenyl]-2-aminopropane (DOI), a se
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45199c70fb8f86ca26a5c699bacd3209
https://doi.org/10.1538/expanim.59.441
https://doi.org/10.1538/expanim.59.441
Publikováno v:
Journal of Molecular Neuroscience. 41:223-229
It has been reported earlier that interactions between Cav2.1α1 and calcium/calmodulin-dependent protein kinase II (CaMKII) in the presynaptic fraction and between the NMDA receptor subunit NR2B and CaMKII in the postsynaptic density (PSD) fraction
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c4409422496a7c1b5ff0f56b48f1b990
https://doi.org/10.1007/s12031-009-9216-5
https://doi.org/10.1007/s12031-009-9216-5
Publikováno v:
Physiology & Behavior. 96:464-469
The motor function of senescence-accelerated mouse prone 6 (SAMP6) was evaluated with a battery of behavioral tests: locomotor activity test, traction test, wire hanging test, and rotating rod test. SAMP6 exhibited increased locomotor activity compar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f5701640ab93ad84cdc89bb79aab958
https://doi.org/10.1016/j.physbeh.2008.11.012
https://doi.org/10.1016/j.physbeh.2008.11.012
Publikováno v:
Neuroscience Letters. 444:60-63
Senescence accelerated prone mouse 6 (SAMP6) mice have been known to be a model for accelerated aging. Compared with the normal control senescence accelerated resistant mouse 1 (SAMR1) mice, although the SAMP6 mice have normal bone mass at 4 months,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::351b42036db7adad10a0af5ad98388ed
https://doi.org/10.1016/j.neulet.2008.08.003
https://doi.org/10.1016/j.neulet.2008.08.003
Publikováno v:
Behavioural Brain Research. 188:329-336
Senescence-accelerated prone mouse 6 (SAMP6) is a model for senile osteoporosis. It was recently reported that SAMP6 has a memory deficit in the water maze test. Because emotion and cognition are thought to interact, in the present study to examine e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c5acda5a353c540620ddd23a2d847ba
https://doi.org/10.1016/j.bbr.2007.11.014
https://doi.org/10.1016/j.bbr.2007.11.014
Publikováno v:
Journal of Veterinary Medical Science. 67:411-416
Bovine ephemeral fever (BEF), a vector-borne disease of cattle, is caused by the Ephemerovirus of the family Rhabdoviridae. In the past 40 years, Taiwan has had seven BEF epizootics, and we have previously reported the first five. This study summariz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6bf2b5c9399b21080365a52e7d84ac1c
https://doi.org/10.1292/jvms.67.411
https://doi.org/10.1292/jvms.67.411