Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Chitose Yoshimura-Uchiyama"'
Autor:
Maho Suzukawa, Kazuhiko Yamamoto, Hirokazu Yamada, Masao Yamaguchi, Chitose Yoshimura-Uchiyama, Hiroshi Kawasaki, Hiroyuki Nagase, Akiko Komiya, Ken Ohta, Koichi Hirai, Kouji Matsushima, Motoyasu Iikura
Publikováno v:
International Immunology. 18:1575-1583
In allergic disorders, basophils migrate from the blood stream to inflamed tissue sites. Since trans-basement membrane migration is an important step for local basophil accumulation, we performed a human basophil transmigration assay using a model ba
Autor:
Motoyasu Iikura, Chitose Yoshimura-Uchiyama, Masao Yamaguchi, Kouji Matsushima, Koichi Hirai, Kazuhiko Yamamoto, Akiko Komiya, Maho Suzukawa, Takashi Sekiya, Hiroyuki Nagase
Publikováno v:
Journal of Allergy and Clinical Immunology. 116:578-585
Background 5-Lipoxygenase (5-LO) products have been strongly implicated in the pathogenesis of allergic diseases. In addition to their physiologic effects on residential cells, 5-LO products are capable of stimulating various eosinophil functions. Ho
Autor:
Maho Suzukawa, Kazuhiko Yamamoto, Chisei Ra, Motoyasu Iikura, Akiko Komiya, Hirokazu Yamada, Chitose Yoshimura-Uchiyama, Hiroyuki Nagase, Koichi Hirai, Masao Yamaguchi, Ken Ohta
Publikováno v:
International Immunology. 17:1249-1255
Local accumulation of basophils at inflammatory sites is observed in experimental antigen challenge and in allergic diseases. It is not fully known what factor(s) regulates local basophil influx in tissues, and it has not been determined whether anti
Autor:
Akira Ishii, K. B. Bacon, Motoyasu Iikura, Chitose Yoshimura-Uchiyama, Hiroyuki Nagase, Koichi Hirai, Keiichiro Yamamoto, Munehiro Yamaguchi, Michitaka Shichijo, Koji Matsushima
Publikováno v:
Clinical Experimental Allergy. 34:1283-1290
Summary Background Both prostaglandin (PG) D receptor (DP) and CRTH2 (chemoattractant receptor-homologous molecule expressed on Th2 cells)/DP2 are high-affinity receptors for PGD2. Previous studies have demonstrated that PGD2 enhances releasability a
Autor:
Akiko Komiya, Masao Yamaguchi, Chitose Yoshimura-Uchiyama, Hirokazu Yamada, Chisei Ra, Hiroyuki Nagase, Rikiya Koketsu, Maho Suzukawa, Ayako Kawakami, Kazuhiko Yamamoto, Motoyasu Iikura, Ken Ohta
Publikováno v:
International archives of allergy and immunology. 143
Surface-expressed CD69 is a recently recognized activation marker for basophils and is reported to be strongly induced in vitro by IL-3. In this study, we investigated whether IgE- and high-affinity receptor for IgE (FcΕRI)-dependent stimuli can aff
Autor:
Kouji Matsushima, Koichi Hirai, Takashi Igarashi, Masao Yamaguchi, Tsutomu Iwata, Kazuhiko Yamamoto, Hiroyuki Nagase, Chitose Yoshimura-Uchiyama
Publikováno v:
Biochemical and biophysical research communications. 309(1)
IL-3, IL-5, and GM-CSF exert overlapping functions in eosinophils via a shared receptor beta-chain, and IL-3Ralpha transcript expression is the weakest in blood eosinophils. We investigated the long-term regulation of surface expression of IL-3Ralpha
Autor:
Takao Fujisawa, Masao Yamaguchi, Chitose Yoshimura-Uchiyama, Koichi Hirai, Kouji Matsushima, Chisei Ra, Kazuhiko Yamamoto, Tsutomu Iwata, Hiroyuki Nagase, Takashi Igarashi
Publikováno v:
Biochemical and biophysical research communications. 302(2)
IL-3, IL-5, and GM-CSF exert various overlapping functions in basophils. We investigated the receptor expression profiles and concentration-dependent effects of IL-3, IL-5, and GM-CSF on several basophil functions in comparison with their effects on
Autor:
Tetsuya Adachi, Motoyasu Iikura, Hiroki Shoji, Shintaro Suzuki, Yoshiko Sasaki, Takanori Nakamura, Kazuhisa Takahashi, Kyoko Nohtomi, Rika Shinonaga, Mio Kawaguchi, Hirokazu Yamada, Tsuyoshi Kasama, Chitose Yoshimura-Uchiyama, Yotaro Takaku, Takeshi Nabe, Shin-ichiro Kagami, Hiroyuki Nagase, Yuichiro Kajiyama, Teizo Yoshimura, Yumiko Kamada, Hiroyuki Kayaba, Kazuhiko Yamamoto, Robert P. Schleimer, Masahide Takeda, Tomomi Tanigai, Kenji Matsumoto, JangJa Hong, Tomomi Hashimoto, Osamu Kaminuma, Shuhei Fukuda, Shinya Kikuchi, Akira Kanda, Wataru Ito, Hideki Tatsumi, Koichi Hagiwara, Kazuo Ohuchi, Shigeharu Ueki, Fujiko Kitamura, Matsunobu Suko, Takahito Chiba, Makiko Umezu-Goto, Yumiko Kashio, Masatsugu Kurokawa, Chisei Ra, Yasushi Saito, Hidekazu Ota, Hiroshi Nakajima, Hajime Oyamada, Masao Yamaguchi, Miho Odaka, Nozomu Nishi, Yoshinosuke Fukuchi, Makoto Nagata, Hiroko Takeuchi, Kazutoshi Yamaguchi, Takehito Kobayashi, Rikiya Koketsu, Hideki Kuga, Motohiro Ebisawa, Noriyasu Hirasawa, Ok Pyo Zee, Tomohiro Tamachi, Ken Ohta, Maho Suzukawa, Mitsuomi Hirashima, Hikari Kato, Satoshi Matsukura, Noriko Kitamura, Ayako Kawakami, Mitsuru Adachi, Koich Hirose, Aki Takahashi, Shoichiro Miyatake, Soichi Nemoto, Hitomi Yamamoto, Hirohisa Saito, Izumi Kikuchi, Koushi Ieki, Hiroshi Tachimoto, Shin Watanabe, Shigekatsu Kohno, Akio Mori, Tetsuya Homma, Junichi Chihara, Maki Terakawa, Akiko Komiya, Motoko Kaneko, Shau-Ku Huang, Minoru Kanazawa, Yoshiki Kobayashi, Simon P. Hogan, Fumio Kokubu, Norihiko Watanabe, Yoshihiro Oya, Itsuo Iwamoto, Koshi Ieki, Kenji Ishihara, Noriaki Kobayashi, Tomoyuki Soma
Publikováno v:
International Archives of Allergy and Immunology. 143:114-114
Autor:
Motoyasu Iikura, Chitose Yoshimura-Uchiyama, Kouji Matsushima, Keiichiro Yamamoto, Michitaka Shichijo, Hiroyuki Nagase, Koichi Hirai, K. B. Bacon, Akira Ishii, Munehiko Yamaguchi
Publikováno v:
Journal of Allergy and Clinical Immunology. 113:S101
Rationale Both PGD receptor (DP) and CRTH2 (chemoattractant receptor-homologous molecule expressed on Th2 cells)/DP2 are high-affinity receptors for PGD 2 . Previous studies have demonstrated that PGD 2 enhances releasability and induces CRTH2/DP2-me