Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Chitoku Toda"'
Autor:
Ming-Liang Lee, Hirokazu Matsunaga, Yuki Sugiura, Takahiro Hayasaka, Izumi Yamamoto, Taiga Ishimoto, Daigo Imoto, Makoto Suematsu, Norifumi Iijima, Kazuhiro Kimura, Sabrina Diano, Chitoku Toda
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
The ventromedial hypothalamus regulates systemic glucose metabolism. Here the authors show that cytosolic phospholipase A2 mediated phospholipid metabolism contributes to this regulation in healthy animals but exert deteriorating effects on glucose h
Externí odkaz:
https://doaj.org/article/d75bb48442764a558ebec50556d76a3e
Publikováno v:
Frontiers in Physiology, Vol 12 (2022)
Externí odkaz:
https://doaj.org/article/fecd8673f46042dba256a18fe1087007
Autor:
Daigo Imoto, Izumi Yamamoto, Hirokazu Matsunaga, Toya Yonekura, Ming-Liang Lee, Kan X. Kato, Takeshi Yamasaki, Shucheng Xu, Taiga Ishimoto, Satoshi Yamagata, Ken-ichi Otsuguro, Motohiro Horiuchi, Norifumi Iijima, Kazuhiro Kimura, Chitoku Toda
Publikováno v:
Molecular Metabolism, Vol 54, Iss , Pp 101366- (2021)
Objective: The regulation of food intake is a major research area in the study of obesity, which plays a key role in the development of metabolic syndrome. Gene targeting studies have clarified the roles of hypothalamic neurons in feeding behavior, b
Externí odkaz:
https://doaj.org/article/e4073d3d75374f94930b616d55d069ef
Autor:
Shiki Okamoto, Tatsuya Sato, Michihiro Tateyama, Haruaki Kageyama, Yuko Maejima, Masanori Nakata, Satoshi Hirako, Takashi Matsuo, Sanda Kyaw, Tetsuya Shiuchi, Chitoku Toda, Udval Sedbazar, Kumiko Saito, Nur Farehan Asgar, Boyang Zhang, Shigefumi Yokota, Kenta Kobayashi, Fabienne Foufelle, Pascal Ferré, Masamitsu Nakazato, Hiroaki Masuzaki, Seiji Shioda, Toshihiko Yada, Barbara B. Kahn, Yasuhiko Minokoshi
Publikováno v:
Cell Reports, Vol 22, Iss 3, Pp 706-721 (2018)
Food selection is essential for metabolic homeostasis and is influenced by nutritional state, food palatability, and social factors such as stress. However, the mechanism responsible for selection between a high-carbohydrate diet (HCD) and a high-fat
Externí odkaz:
https://doaj.org/article/90df534131bd4d7b9587b674521bbbf1
Autor:
Natsuko Saito, Shunsuke Kimura, Tomomi Miyamoto, Sanae Fukushima, Misato Amagasa, Yoshinori Shimamoto, Chieko Nishioka, Shiki Okamoto, Chitoku Toda, Kohei Washio, Atsushi Asano, Ichiro Miyoshi, Eiki Takahashi, Hiroshi Kitamura
Publikováno v:
Biochemistry and Biophysics Reports, Vol 9, Iss C, Pp 322-329 (2017)
We previously reported that ubiquitin-specific protease (USP) 2 in macrophages down-regulates genes associated with metabolic diseases, suggesting a putative anti-diabetic role for USP2 in macrophages. In this study, we evaluate this role at both cel
Externí odkaz:
https://doaj.org/article/f2bf2c95144646929de023d6521dbddb
Publikováno v:
Indian Journal of Endocrinology and Metabolism, Vol 16, Iss 9, Pp 562-568 (2012)
Leptin is a hormone secreted by adipocytes that plays a pivotal role in regulation of food intake, energy expenditure, and neuroendocrine function. Several lines of evidences indicate that independent of the anorexic effect, leptin regulates glucose
Externí odkaz:
https://doaj.org/article/dffe2002fe6c4c3d90dec8e2d32b3a96
Autor:
Mayuko Hashimoto, Masaki Fujimoto, Kohtarou Konno, Ming-Liang Lee, Yui Yamada, Koya Yamashita, Chitoku Toda, Michio Tomura, Masahiko Watanabe, Osamu Inanami, Hiroshi Kitamura
Publikováno v:
J Neurosci
Ubiquitin-specific protease 2 (USP2) participates in glucose metabolism in peripheral tissues such as the liver and skeletal muscles. However, the glucoregulatory role of USP2 in the CNS is not well known. In this study, we focus on USP2 in the ventr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32806fd19d9cb198a318cd70b0a542bc
https://europepmc.org/articles/PMC9186793/
https://europepmc.org/articles/PMC9186793/
Autor:
Izumi Yamamoto, Toya Yonekura, Taiga Ishimoto, Shu-Cheng Xu, Norifumi Iijima, Kazuhiro Kimura, Sabrina Diano, Chitoku Toda
Anticipatory physiological responses to food were first reported by Ivan Pavlov a century ago but the associated neural mechanism is still ill-defined. Here, we identified two types of neurons in the basolateral amygdala (BLA), which are activated by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0e2518203485e69a961c355be74da392
https://doi.org/10.1101/2022.02.03.479066
https://doi.org/10.1101/2022.02.03.479066
Publikováno v:
Frontiers in Physiology, Vol 12 (2022)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96b1c6dc8e1cc7a5bd772866eb3558d9
https://pubmed.ncbi.nlm.nih.gov/35153823
https://pubmed.ncbi.nlm.nih.gov/35153823
Autor:
Ming-Liang Lee, Motohiro Horiuchi, Norifumi Iijima, Takeshi Yamasaki, Ken-ichi Otsuguro, Kazuhiro Kimura, Hirokazu Matsunaga, Chitoku Toda, Toya Yonekura, Daigo Imoto, Kan X. Kato, Izumi Yamamoto
The regulation of food intake is one of the major research areas in the study of metabolic syndromes such as obesity. Gene targeting studies have clarified the roles of hypothalamic neurons in feeding behaviour. However, our understanding of neural f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1ed277ef6031676f59727a1bb07af878
https://doi.org/10.1101/2020.07.02.183780
https://doi.org/10.1101/2020.07.02.183780