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Accelerator-Based Production of Scandium Radioisotopes for Applications in Prostate Cancer: Toward Building a Pipeline for Rapid Development of Novel Theranostics.

Autor: Meier JP; Department of Radiology, The University of Chicago, Chicago, IL 60637, USA., Zhang HJ; Department of Radiology, The University of Chicago, Chicago, IL 60637, USA.; Integrated Small Animal Imaging Research Resource, Office of Shared Research Facilities, The University of Chicago, Chicago, IL 60637, USA., Freifelder R; Department of Radiology, The University of Chicago, Chicago, IL 60637, USA.; Cyclotron Facility, The University of Chicago, Chicago, IL 60637, USA.; UChicago/Argonne Joint Radioisotope Initiative (JRI), Chicago, IL 60637, USA., Bhuiyan M; Department of Radiology, The University of Chicago, Chicago, IL 60637, USA.; Cyclotron Facility, The University of Chicago, Chicago, IL 60637, USA., Selman P; Department of Medicine, The University of Chicago, Chicago, IL 60637, USA., Mendez M; Department of Medicine, The University of Chicago, Chicago, IL 60637, USA., Kankanamalage PHA; Physics Division, Argonne National Laboratory, Lemont, IL 60439, USA.; Collider Accelerator Department, Brookhaven National Laboratory, Upton, NY 11973, USA., Brossard T; Physics Division, Argonne National Laboratory, Lemont, IL 60439, USA., Pusateri A; Department of Radiology, The University of Chicago, Chicago, IL 60637, USA., Tsai HM; Integrated Small Animal Imaging Research Resource, Office of Shared Research Facilities, The University of Chicago, Chicago, IL 60637, USA., Leoni L; Integrated Small Animal Imaging Research Resource, Office of Shared Research Facilities, The University of Chicago, Chicago, IL 60637, USA., Penano S; Department of Radiology, The University of Chicago, Chicago, IL 60637, USA., Ghosh K; Department of Radiology, The University of Chicago, Chicago, IL 60637, USA.; Cyclotron Facility, The University of Chicago, Chicago, IL 60637, USA., Broder BA; Department of Radiology, The University of Chicago, Chicago, IL 60637, USA.; National Institute of Standards and Technology, Gaithersburg, MD 20899, USA., Markiewicz E; Integrated Small Animal Imaging Research Resource, Office of Shared Research Facilities, The University of Chicago, Chicago, IL 60637, USA., Renne A; Department of Radiology, The University of Chicago, Chicago, IL 60637, USA.; Physics Division, Argonne National Laboratory, Lemont, IL 60439, USA., Stadler W; UChicago/Argonne Joint Radioisotope Initiative (JRI), Chicago, IL 60637, USA.; Department of Medicine, The University of Chicago, Chicago, IL 60637, USA., Weichselbaum R; UChicago/Argonne Joint Radioisotope Initiative (JRI), Chicago, IL 60637, USA.; Department of Radiation and Cellular Oncology, The University of Chicago, Chicago, IL 60637, USA., Nolen J; UChicago/Argonne Joint Radioisotope Initiative (JRI), Chicago, IL 60637, USA.; Physics Division, Argonne National Laboratory, Lemont, IL 60439, USA., Kao CM; Department of Radiology, The University of Chicago, Chicago, IL 60637, USA.; Integrated Small Animal Imaging Research Resource, Office of Shared Research Facilities, The University of Chicago, Chicago, IL 60637, USA.; UChicago/Argonne Joint Radioisotope Initiative (JRI), Chicago, IL 60637, USA., Chitneni SK; Department of Radiology, The University of Chicago, Chicago, IL 60637, USA., Rotsch DA; UChicago/Argonne Joint Radioisotope Initiative (JRI), Chicago, IL 60637, USA.; Physics Division, Argonne National Laboratory, Lemont, IL 60439, USA.; Medical Isotope Development Group, Oak Ridge National Laboratory, Oak Ridge, TN 37830, USA., Szmulewitz RZ; UChicago/Argonne Joint Radioisotope Initiative (JRI), Chicago, IL 60637, USA.; Department of Medicine, The University of Chicago, Chicago, IL 60637, USA., Chen CT; Department of Radiology, The University of Chicago, Chicago, IL 60637, USA.; Integrated Small Animal Imaging Research Resource, Office of Shared Research Facilities, The University of Chicago, Chicago, IL 60637, USA.; Cyclotron Facility, The University of Chicago, Chicago, IL 60637, USA.; UChicago/Argonne Joint Radioisotope Initiative (JRI), Chicago, IL 60637, USA.

Publikováno v: Molecules (Basel, Switzerland) [Molecules] 2023 Aug 13; Vol. 28 (16). Date of Electronic Publication: 2023 Aug 13.

Fluorine-18 Labeling of the MDM2 Inhibitor RG7388 for PET Imaging: Chemistry and Preliminary Evaluation.

Autor: Zhou Z; Department of Radiology, Duke University Medical Center, Durham, North Carolina 27710, United States., Zalutsky MR; Department of Radiology, Duke University Medical Center, Durham, North Carolina 27710, United States., Chitneni SK; Department of Radiology, Duke University Medical Center, Durham, North Carolina 27710, United States.

Publikováno v: Molecular pharmaceutics [Mol Pharm] 2021 Oct 04; Vol. 18 (10), pp. 3871-3881. Date of Electronic Publication: 2021 Sep 15.

Increased Glutaminolysis Marks Active Scarring in Nonalcoholic Steatohepatitis Progression.

Autor: Du K; Division of Gastroenterology, Duke University, Durham, North Carolina., Chitneni SK; Department of Radiology, Duke University, Durham, North Carolina., Suzuki A; Division of Gastroenterology, Duke University, Durham, North Carolina., Wang Y; Division of Gastroenterology, Duke University, Durham, North Carolina., Henao R; Department of Electrical and Computer Engineering, Duke University, Durham, North Carolina., Hyun J; Division of Gastroenterology, Duke University, Durham, North Carolina., Premont RT; Division of Gastroenterology, Duke University, Durham, North Carolina., Naggie S; Division of Infectious Diseases, Department of Medicine, Duke University, Durham, North Carolina., Moylan CA; Division of Gastroenterology, Duke University, Durham, North Carolina., Bashir MR; Division of Gastroenterology, Duke University, Durham, North Carolina; Department of Radiology, Duke University, Durham, North Carolina; Center for Advanced Magnetic Resonance Development, Duke University, Durham, North Carolina., Abdelmalek MF; Division of Gastroenterology, Duke University, Durham, North Carolina., Diehl AM; Division of Gastroenterology, Duke University, Durham, North Carolina. Electronic address: annamae.diehl@duke.edu.

Publikováno v: Cellular and molecular gastroenterology and hepatology [Cell Mol Gastroenterol Hepatol] 2020; Vol. 10 (1), pp. 1-21. Date of Electronic Publication: 2019 Dec 25.

A Rationally Designed Fully Human EGFRvIII:CD3-Targeted Bispecific Antibody Redirects Human T Cells to Treat Patient-derived Intracerebral Malignant Glioma.

Autor: Gedeon PC; Duke Brain Tumor Immunotherapy Program, Department of Neurosurgery, Duke University Medical Center, Durham, North Carolina.; Department of Biomedical Engineering, Duke University, Durham, North Carolina.; The Preston Robert Tisch Brain Tumor Center, Department of Neurosurgery, Duke University Medical Center, Durham, North Carolina., Schaller TH; Duke Brain Tumor Immunotherapy Program, Department of Neurosurgery, Duke University Medical Center, Durham, North Carolina.; The Preston Robert Tisch Brain Tumor Center, Department of Neurosurgery, Duke University Medical Center, Durham, North Carolina.; Department of Pathology, Duke University Medical Center, Durham, North Carolina., Chitneni SK; Department of Radiology, Duke University Medical Center, Durham, North Carolina., Choi BD; Duke Brain Tumor Immunotherapy Program, Department of Neurosurgery, Duke University Medical Center, Durham, North Carolina.; The Preston Robert Tisch Brain Tumor Center, Department of Neurosurgery, Duke University Medical Center, Durham, North Carolina.; Department of Pathology, Duke University Medical Center, Durham, North Carolina., Kuan CT; Duke Brain Tumor Immunotherapy Program, Department of Neurosurgery, Duke University Medical Center, Durham, North Carolina.; The Preston Robert Tisch Brain Tumor Center, Department of Neurosurgery, Duke University Medical Center, Durham, North Carolina.; Department of Pathology, Duke University Medical Center, Durham, North Carolina., Suryadevara CM; Duke Brain Tumor Immunotherapy Program, Department of Neurosurgery, Duke University Medical Center, Durham, North Carolina.; The Preston Robert Tisch Brain Tumor Center, Department of Neurosurgery, Duke University Medical Center, Durham, North Carolina.; Department of Pathology, Duke University Medical Center, Durham, North Carolina., Snyder DJ; Duke Brain Tumor Immunotherapy Program, Department of Neurosurgery, Duke University Medical Center, Durham, North Carolina.; The Preston Robert Tisch Brain Tumor Center, Department of Neurosurgery, Duke University Medical Center, Durham, North Carolina., Schmittling RJ; Duke Brain Tumor Immunotherapy Program, Department of Neurosurgery, Duke University Medical Center, Durham, North Carolina.; The Preston Robert Tisch Brain Tumor Center, Department of Neurosurgery, Duke University Medical Center, Durham, North Carolina., Szafranski SE; Duke Brain Tumor Immunotherapy Program, Department of Neurosurgery, Duke University Medical Center, Durham, North Carolina.; The Preston Robert Tisch Brain Tumor Center, Department of Neurosurgery, Duke University Medical Center, Durham, North Carolina., Cui X; Duke Brain Tumor Immunotherapy Program, Department of Neurosurgery, Duke University Medical Center, Durham, North Carolina.; The Preston Robert Tisch Brain Tumor Center, Department of Neurosurgery, Duke University Medical Center, Durham, North Carolina., Healy PN; Department of Biostatistics and Bioinformatics, Duke University Medical Center, Durham, North Carolina., Herndon JE 2nd; Department of Biostatistics and Bioinformatics, Duke University Medical Center, Durham, North Carolina., McLendon RE; Department of Pathology, Duke University Medical Center, Durham, North Carolina., Keir ST; Duke Brain Tumor Immunotherapy Program, Department of Neurosurgery, Duke University Medical Center, Durham, North Carolina.; The Preston Robert Tisch Brain Tumor Center, Department of Neurosurgery, Duke University Medical Center, Durham, North Carolina., Archer GE; Duke Brain Tumor Immunotherapy Program, Department of Neurosurgery, Duke University Medical Center, Durham, North Carolina.; The Preston Robert Tisch Brain Tumor Center, Department of Neurosurgery, Duke University Medical Center, Durham, North Carolina., Reap EA; Duke Brain Tumor Immunotherapy Program, Department of Neurosurgery, Duke University Medical Center, Durham, North Carolina.; The Preston Robert Tisch Brain Tumor Center, Department of Neurosurgery, Duke University Medical Center, Durham, North Carolina., Sanchez-Perez L; Duke Brain Tumor Immunotherapy Program, Department of Neurosurgery, Duke University Medical Center, Durham, North Carolina.; The Preston Robert Tisch Brain Tumor Center, Department of Neurosurgery, Duke University Medical Center, Durham, North Carolina., Bigner DD; Duke Brain Tumor Immunotherapy Program, Department of Neurosurgery, Duke University Medical Center, Durham, North Carolina.; The Preston Robert Tisch Brain Tumor Center, Department of Neurosurgery, Duke University Medical Center, Durham, North Carolina.; Department of Pathology, Duke University Medical Center, Durham, North Carolina., Sampson JH; Duke Brain Tumor Immunotherapy Program, Department of Neurosurgery, Duke University Medical Center, Durham, North Carolina. john.sampson@duke.edu.; Department of Biomedical Engineering, Duke University, Durham, North Carolina.; The Preston Robert Tisch Brain Tumor Center, Department of Neurosurgery, Duke University Medical Center, Durham, North Carolina.; Department of Pathology, Duke University Medical Center, Durham, North Carolina.

Publikováno v: Clinical cancer research : an official journal of the American Association for Cancer Research [Clin Cancer Res] 2018 Aug 01; Vol. 24 (15), pp. 3611-3631. Date of Electronic Publication: 2018 Apr 27.