Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Chithra Muraleedharan"'
Publikováno v:
Journal of Global Antimicrobial Resistance. 16:225-235
Objective The aim of this study was to determine whether Clinton River water is contaminated with antibiotics and is a reservoir of antimicrobial-resistant bacteria. Methods Water samples were taken from two sites of Clinton River. Antimicrobial-resi
Autor:
Chithra Muraleedharan, Sharon A. McClellan, Sandamali A. Ekanayaka, Shunbin Xu, Rebecca Francis, Linda D. Hazlett, Alex Zmejkoski
Publikováno v:
Journal of Innate Immunity. 11:347-358
Macrophages (Mϕ) are an important component of the innate immune system; they play critical roles in the first line of defense to pathogen invasion and modulate adaptive immunity. MicroRNAs (miRNAs) are a newly recognized, important level of gene ex
Autor:
Kerry Goetz, William J. Garcia, Weifeng Li, Eric Mishulin, Chithra Muraleedharan, Ardian Coku, Ali Harajli, Shunbin Xu, David G. Birch, Chafic Dahabra, Joanne Choi, Kaylie D. Webb
Publikováno v:
Frontiers in Cell and Developmental Biology
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Inherited retinal dystrophy (IRD) is a heterogenous blinding eye disease and affects more than 200,000 Americans and millions worldwide. By far, 270 protein-coding genes have been identified to cause IRD when defective. However, only one microRNA (mi
Autor:
Jinsheng Zhang, Chithra Muraleedharan, David N. Furness, Ruishuang Geng, Shunbin Xu, Vincent Lin, Alain Dabdoub
Publikováno v:
Scientific Reports
Scientific Reports, Vol 8, Iss 1, Pp 1-13 (2018)
Scientific Reports, Vol 8, Iss 1, Pp 1-13 (2018)
The microRNA (miR)-183/96/182 cluster plays important roles in the development and functions of sensory organs, including the inner ear. Point-mutations in the seed sequence of miR-96 result in non-syndromic hearing loss in both mice and humans. Howe
Autor:
Ronald P. Barrett, Shunbin Xu, Daniel Montenegro, Thomas W Carion, Cui Li, Chithra Muraleedharan, Linda D. Hazlett, Sharon A. McClellan, Elizabeth A. Berger
Publikováno v:
Investigative Ophthalmology & Visual Science
PURPOSE The microRNA-183/96/182 cluster (miR-183/96/182) plays important roles in sensory organs. Because the cornea is replete with sensory innervation, we hypothesized that miR-183/96/182 modulates the corneal response to bacterial infection throug
Publikováno v:
Investigative Opthalmology & Visual Science. 58:1646
Purpose Previously, we showed that microRNA-146 (miR-146) is a pivotal negative feedback regulator of multiple nuclear factor kappa-B (NF-κB) activation pathways in retinal endothelial cells (RECs). We hypothesized that miR-146 plays an important ro
Autor:
Natasha Bhutani, Chithra Muraleedharan, Satish K. Walia, Sandeep Walia, Sonia Rana, Deepa Talreja, Ashok Kumar
Publikováno v:
BioMed Research International
BioMed Research International, Vol 2015 (2015)
BioMed Research International, Vol 2015 (2015)
Antibiotic resistance in bacteria is a global problem exacerbated by the dissemination of resistant bacteria via uncooked food, such as green leafy vegetables. New strains of bacteria are emerging on a daily basis with novel expanded antibiotic resis
Autor:
Yifan Zhang, Satish K. Walia, Deepa Talreja, Ashok Kumar, Keith S. Kaye, Chithra Muraleedharan, Gayathri Upeksha Gunathilaka
Publikováno v:
Current eye research. 39(7)
Acinetobacter (A.) baumannii is an opportunistic pathogen and has been reported as a causative agent of ocular infections. The aim of this study is to identify virulence properties (biofilm formation, adhesion, invasion and cytotoxicity) and antibiot
Autor:
Pawan Kumar Singh, Shunbin Xu, Chithra Muraleedharan, Hazel Lum, Colleen Cowan, Ashok Kumar, James O'Donnell
Publikováno v:
Investigative Opthalmology & Visual Science. 55:4944
Purpose Nuclear factor-κB (NF-κB), a key regulator of immune and inflammatory responses, plays important roles in diabetes-induced microvascular complications including diabetic retinopathy (DR). Thrombin activates NF-κB through protease-activated