Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Chithan C Kandaswami"'
Autor:
Yo-Chuen Lin, Pei-Hsun Tsai, Chun-Yu Lin, Chia-Hsiung Cheng, Tsung-Han Lin, Kevin P H Lee, Kai-Yun Huang, Shih-Hsun Chen, Jiuan-Jiuan Hwang, Chithan C Kandaswami, Ming-Ting Lee
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e71903 (2013)
Metastasis is a major cause of mortality in cancer patients. Invadopodia are considered to be crucial structures that allow cancer cells to penetrate across the extracellular matrix (ECM) by using matrix metalloproteinases (MMPs). Previously, we isol
Externí odkaz:
https://doaj.org/article/052f3cfa4a104b9a9eabb995c7fa93bd
Autor:
Cheng-Wei Lin, Gi-Ming Lai, Ku-Chung Chen, Tsung-Han Lin, Jhen-Jia Fan, Rhu-Long Hsu, Chih-Ming Chou, Chun-Mao Lin, Chithan C. Kandaswami, Ming-Ting Lee, Chia-Hsiung Cheng
Publikováno v:
Journal of Functional Foods, Vol 19, Iss , Pp 236-247 (2015)
The dietary flavonoids luteolin and quercetin are reported to inhibit cancer mobility; however, the regulatory effect of luteolin and quercetin on RPS12 is still unclear. Here, we found that A431-III cells expressed a higher level of RPS12 than A431-
Externí odkaz:
https://doaj.org/article/c41f89b55b24484180023750d328c5e3
Autor:
Cheng-Wei Lin, Gi-Ming Lai, Ku-Chung Chen, Tsung-Han Lin, Jhen-Jia Fan, Rhu-Long Hsu, Chih-Ming Chou, Chun-Mao Lin, Chithan C. Kandaswami, Ming-Ting Lee, Chia-Hsiung Cheng
Publikováno v:
Journal of Functional Foods, Vol 29, Iss , Pp 303- (2017)
Externí odkaz:
https://doaj.org/article/21a26949e3f7458bb96d104cc3ef4b35
Autor:
Ku Chung Chen, Chithan C. Kandaswami, Cheng Wei Lin, Jhih Yun Ho, Cheng Ying Chu, Ming Ting Lee, Wen Hsien Hsu, Chia Hsiung Cheng
Publikováno v:
Journal of Food and Drug Analysis, Vol 26, Iss 3, Pp 1180-1191 (2018)
Flavonoids luteolin and quercetin can inhibit growth and metastasis of cancer cells. In our previous report, luteolin and quercetin was shown to block Akt/mTOR/c-Myc signaling. Here, we found luteolin and quercetin reduced protein level and transacti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79da787010a0b6dd9f4996e0b3100caf
http://www.sciencedirect.com/science/article/pii/S1021949818300401
http://www.sciencedirect.com/science/article/pii/S1021949818300401
Autor:
Cheng Wei Lin, Tsung Han Lin, Ming Ting Lee, Geen-Dong Chang, Wen Hsien Hsu, Pei Hsun Tsai, Chithan C. Kandaswami, Ku Chung Chen, Ying Tang Huang, Inn Ho Tsai, Chia Hsiung Cheng, Chang Jen Huang
Publikováno v:
Food & Function. 8:1558-1568
We previously reported that the dietary flavonoids, luteolin and quercetin, might inhibit the invasiveness of cervical cancer by reversing epithelial-mesenchymal transition (EMT) signaling. However, the regulatory mechanism exerted by luteolin and qu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::091ffb1a065ac688c466e6cdd801832c
https://doi.org/10.1039/c6fo00551a
https://doi.org/10.1039/c6fo00551a
Autor:
Geen-Dong Chang, Pei Hsun Tsai, Chin-Chun Hung, Ferng Chun Ke, Lung Ta Lee, Chithan C. Kandaswami, Ying Tang Huang, Chun Yu Lin, Ming Ting Lee, Kevin Po Hao Lee, Jiuan Jiuan Hwang, Yo Chuen Lin, Chia Hsiung Cheng
Publikováno v:
Anticancer research. 36(12)
A highly invasive Du145-III subline was isolated by three successive passages of the parental Du145 prostate tumor cell line (Du145-P) through a Boyden chamber with matrigel-coated membrane support. Du145-III cells showed great invasion potential bas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c6e2f2e951fdc738a6309e45a66e4d6
https://pubmed.ncbi.nlm.nih.gov/27919958
https://pubmed.ncbi.nlm.nih.gov/27919958
Autor:
Pei Hsun Tsai, Chun Yu Lin, Ping Ping Lee, Chang Jen Huang, Ming Ting Lee, Chithan C. Kandaswami, Jiuan Jiuan Hwang
Publikováno v:
Cancer Science. 102:815-827
One of the most fundamental biological processes in tumor metastasis is the process of epithelial–mesenchymal transition (EMT). During EMT, zinc-finger-family of transcription factors such as Snail, Slug and Twist, and matrix metalloproteinases (MM
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e426f4794d5d34b8e99ee8183e66a40e
https://doi.org/10.1111/j.1349-7006.2011.01861.x
https://doi.org/10.1111/j.1349-7006.2011.01861.x
Autor:
Ravikumar Aalinkeel, Jessica L. Reynolds, Madhavan Nair, Supriya D. Mahajan, Hari Krishnan Nair, Chithan C. Kandaswami, Stanley A. Schwartz
Publikováno v:
Clinical and Vaccine Immunology. 13:319-328
The flavonoids comprise a large class of low-molecular-weight plant metabolites ubiquitously distributed in food plants. These dietary antioxidants exert significant antitumor, antiallergic, and anti-inflammatory effects. The molecular mechanisms of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d417a3bb43a4bd78c0bc9ea0d5abebaa
https://doi.org/10.1128/cvi.13.3.319-328.2006
https://doi.org/10.1128/cvi.13.3.319-328.2006
Autor:
Ming Ting Lee, Chang Jen Huang, Jiuan Jiuan Hwang, Ying Tang Huang, Amy Y.L. Lee, Ferng Chun Ke, Lung Ta Lee, Ping Ping H. Lee, Chithan C. Kandaswami
Publikováno v:
Biochemical Pharmacology. 67:2103-2114
Focal adhesion kinase (FAK), a member of a growing family of structurally distinct protein tyrosine kinases (PTK), has been linked to specific phosphorylation events, and the elevation of FAK activity in human carcinoma cells correlated with increase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::643c8e7f3d03ffb7fdd00b696db1c665
https://doi.org/10.1016/j.bcp.2004.02.023
https://doi.org/10.1016/j.bcp.2004.02.023
Autor:
Madhavan Nair, Ram Chawda, Chithan C. Kandaswami, Stanley A. Schwartz, Hari Krishnan Nair, Niranjan Kumar, Supriya D. Mahajan, Kailash C. Chadha, Raji E Nair
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 1593:29-36
Flavonoids are plant metabolites that are dietary antioxidants and exert significant anti-tumor, anti-allergic, anti-inflammatory and anti-viral effects. It is generally accepted that Th-1 derived cytokines such as IL-2, IFNgamma and IL-12 promote ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::854552a4e7a861075fcef2ba10d428b2
https://doi.org/10.1016/s0167-4889(02)00328-2
https://doi.org/10.1016/s0167-4889(02)00328-2