Clofazimine broadly inhibits coronaviruses including SARS-CoV-2

Autor: Jessica Pihl, Jasper Fuk-Woo Chan, Pok Man Lai, Jeffrey D. Esko, Li Sheng, Ronald A. Li, Yushen Du, Ren Sun, Lars Pache, Ronghui Liang, Thomas Mandel Clausen, Kwok-Yung Yuen, Hongzhe Sun, Chun-Kit Yuen, Yuan Pu, Zi-Wei Ye, Chris Chung-Sing Chan, Jianli Cao, Xue-Hui Cai, Anna Jinxia Zhang, Dong Wang, Sumit K. Chanda, Yan-Dong Tang, Ivan Hung, Andrew Chak-Yiu Lee, Wing-Kuk Au, Ko-Yung Sit, Kong-Hung Sze, Vincent Kwok-Man Poon, Dong-Yan Jin, Honglin Chen, Kin-Hang Kok, Runming Wang, Naoko Matsunaga, Wan Xu, Hin Chu, Kaiming Tang, Chit-Ying Lau, Shuofeng Yuan, Juntaek Oh, Chris Chun-Yiu Chan, Laura Riva, Yu-Yuan Zhang, Xiangzhi Meng, Xin Yin

Publikováno v: Yuan, S, Yin, X, Meng, X, Chan, J F W, Ye, Z W, Riva, L, Pache, L, Chan, C C Y, Lai, P M, Chan, C C S, Poon, V K M, Lee, A C Y, Matsunaga, N, Pu, Y, Yuen, C K, Cao, J, Liang, R, Tang, K, Sheng, L, Du, Y, Xu, W, Lau, C Y, Sit, K Y, Au, W K, Wang, R, Zhang, Y Y, Tang, Y D, Clausen, T M, Pihl, J, Oh, J, Sze, K H, Zhang, A J, Chu, H, Kok, K H, Wang, D, Cai, X H, Esko, J D, Hung, I F N, Li, R A, Chen, H, Sun, H, Jin, D Y, Sun, R, Chanda, S K & Yuen, K Y 2021, ' Clofazimine broadly inhibits coronaviruses including SARS-CoV-2 ', Nature, vol. 593, pp. 418–423 . https://doi.org/10.1038/s41586-021-03431-4

The COVID-19 pandemic is the third outbreak this century of a zoonotic disease caused by a coronavirus, following the emergence of severe acute respiratory syndrome (SARS) in 20031 and Middle East respiratory syndrome (MERS) in 20122. Treatment optio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4add8439d17979216ce3a29cb0b95caa
https://doi.org/10.1038/s41586-021-03431-4