Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Chistina Grobin, A"'
Autor:
Chistina Grobin, A ∗, Leslie Morrow, A
Publikováno v:
In Developmental Brain Research 2001 131(1):31-39
Autor:
Chistina Grobin, A c, Inglefield, Jon R d, Schwartz-Bloom, Rochelle D d, Devaud, Leslie L c, Morrow, A.Leslie a, b, c, *
Publikováno v:
In Brain Research 1999 827(1):1-11
Autor:
Lawrence J. Shampine, Marian I. Butterfield, Mark W. Massing, A. Leslie Morrow, Christine E. Marx, Jeffrey A. Lieberman, A. Chistina Grobin, Roger D. Madison, Margaret J. VanDoren, Gary E. Duncan, Daniel W. Bradford
Publikováno v:
Pharmacology Biochemistry and Behavior. 84:598-608
Clozapine demonstrates superior efficacy in patients with schizophrenia, but the precise mechanisms contributing to this clinical advantage are not clear. Clozapine and olanzapine increase the GABAergic neuroactive steroid (NS) allopregnanolone, and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d90444fa92cdf252d65887ac65d20cb
https://doi.org/10.1016/j.pbb.2006.07.026
https://doi.org/10.1016/j.pbb.2006.07.026
Autor:
William T. Trost, Jeffrey A. Lieberman, Mark W. Massing, A. Chistina Grobin, Rahul T. Khisti, Christine E. Marx, A. Leslie Morrow, Lawrence J. Shampine, Daniel W. Bradford, Roger D. Madison, Marian I. Butterfield
Publikováno v:
Pharmacology Biochemistry and Behavior. 84:609-617
Olanzapine and fluoxetine elevate the GABAergic neuroactive steroid allopregnanolone to physiologically relevant concentrations in rodent cerebral cortex. It is unknown if these agents also alter pregnenolone or deoxycorticosterone. Since olanzapine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13c9cae42115338d42da176821962bcc
https://doi.org/10.1016/j.pbb.2006.07.032
https://doi.org/10.1016/j.pbb.2006.07.032
Publikováno v:
Psychopharmacology. 186:334-342
Early life exposure to stress and to GABAA receptor modulators have well-defined and persistent behavioral effects. A single neonatal injection of the GABAergic neurosteroid allopregnanolone (3alpha-hydroxy,5alpha-pregnane-20-one, 10 mg/kg, i.p.) alt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::742f532cf12e6151c493f8ebd3f278f2
https://doi.org/10.1007/s00213-006-0360-0
https://doi.org/10.1007/s00213-006-0360-0
Publikováno v:
Brain Research. 1012:66-74
The neuroactive steroid 3α-hydroxy-5α-pregnane-20-one (allopregnanolone) is a potent endogenous modulator of GABA A receptor function. A single neonatal allopregnanolone administration (10 mg/kg, i.p.) was previously shown to alter the localization
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee5e87a6dbeaec829aa18b9b1ba8e46d
https://doi.org/10.1016/j.brainres.2004.03.049
https://doi.org/10.1016/j.brainres.2004.03.049
Publikováno v:
The Journal of Neuroscience. 23:1832-1839
Neurosteroids are a class of steroids synthesizedde novoin the brain, several of which are potent modulators of GABAAreceptor function. In developing brain GABAAreceptor, stimulation plays a trophic role. Cortical levels of the GABAergic neurosteroid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37bf5e403ae7d7352b812eaf2d4cacde
https://doi.org/10.1523/jneurosci.23-05-01832.2003
https://doi.org/10.1523/jneurosci.23-05-01832.2003
Autor:
A. Chistina Grobin, A. Leslie Morrow
Publikováno v:
Developmental Brain Research. 131:31-39
Despite considerable evidence showing dramatic changes in the plasticity of GABA(A) receptors during neuronal development and studies showing a direct link between neurosteroid concentrations and alterations in GABA(A) receptor expression, little is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f4e8f0260718dbe9d246edaab31e846
https://doi.org/10.1016/s0165-3806(01)00242-5
https://doi.org/10.1016/s0165-3806(01)00242-5
Publikováno v:
Alcoholism: Clinical and Experimental Research. 25:1270-1275
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a3fb92c20a71609fdea3d8c8a289a399
https://doi.org/10.1097/00000374-200109000-00005
https://doi.org/10.1097/00000374-200109000-00005
Publikováno v:
Alcoholism: Clinical and Experimental Research. 25:1270-1275
BACKGROUND Gamma-aminobutyric acid type A (GABA(A)) receptors in the brain are modulated by chronic ethanol exposure via the regulation of their function and expression throughout the central nervous system. Recent studies show that chronic ethanol e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f0aa2ffa99ea5adc37bec10bb73688f9
https://doi.org/10.1111/j.1530-0277.2001.tb02347.x
https://doi.org/10.1111/j.1530-0277.2001.tb02347.x