Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Chisomo L. Msefula"'
Autor:
Chrispin Chaguza, Innocent Chibwe, David Chaima, Patrick Musicha, Latif Ndeketa, Watipaso Kasambara, Chimwemwe Mhango, Upendo L. Mseka, Joseph Bitilinyu-Bangoh, Bernard Mvula, Wakisa Kipandula, Patrick Bonongwe, Richard J. Munthali, Selemani Ngwira, Chikondi A. Mwendera, Akuzike Kalizang’oma, Kondwani C. Jambo, Dzinkambani Kambalame, Arox W. Kamng’ona, A. Duncan Steele, Annie Chauma-Mwale, Daniel Hungerford, Matthew Kagoli, Martin M. Nyaga, Queen Dube, Neil French, Chisomo L. Msefula, Nigel A. Cunliffe, Khuzwayo C. Jere
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Malawi experienced its deadliest Vibrio cholerae (Vc) outbreak following devastating cyclones, with >58,000 cases and >1700 deaths reported between March 2022 and May 2023. Here, we use population genomics to investigate the attributes and o
Externí odkaz:
https://doaj.org/article/6b7cbc3890c14711a1a922c4cd6b9c0a
Autor:
Ritah Nakiboneka, Nicolò Margaritella, Tonney Nyirenda, David Chaima, Natasha Walbaum, Emmanuel Musisi, Sikwese Tionge, Takondwa Msosa, Marriott Nliwasa, Chisomo L. Msefula, Derek Sloan, Wilber Sabiiti
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract The World Health Organization End TB strategy aims for a 90% reduction of tuberculosis (TB) incidence by 2035. Systematic testing and treatment of latent TB infection (LTBI) among contacts of active TB patients is recommended as one of the w
Externí odkaz:
https://doaj.org/article/d27cb087289c4d1fa770d51802bf0042
Autor:
Melita A Gordon, Ellis Owusu-Dabo, Florian Marks, Carsten Mantel, Andrew J Pollard, Brama Hanumunthadu, Rachel White, John A Crump, Hannah Robinson, Jan Jacobs, Samuel Kariuki, Bieke Tack, Stefano Malvolti, Nasir Kanji, Nelly Owino, Carla Ferreira Da Silva, Pietro Ferruzzi, Usman Nakakana, Rocio Canals, Maheshi Ramasamy, Francis Agyapong, Gianluca Breghi, Fabio Fiorino, Christian S. Marchello, Donata Medaglini, Esther M. Muthumbi, Chisomo L. Msefula, Tonney S. Nyirenda, Robert Onsare, Elena Pettini, Anthony G Scott J, Bassiahi Abdramane Soura, Tiziana Spadafina
Publikováno v:
BMJ Open, Vol 13, Iss 11 (2023)
Introduction Invasive non-typhoidal Salmonellosis (iNTS) is mainly caused by Salmonella enterica serovars Typhimurium and Enteritidis and is estimated to result in 77 500 deaths per year, disproportionately affecting children under 5 years of age in
Externí odkaz:
https://doaj.org/article/7f29c2eaf5e042f4a8bfa23fb84777a2
Autor:
James J. Gilchrist, Anna Rautanen, Benjamin P. Fairfax, Tara C. Mills, Vivek Naranbhai, Holly Trochet, Matti Pirinen, Esther Muthumbi, Salim Mwarumba, Patricia Njuguna, Neema Mturi, Chisomo L. Msefula, Esther N. Gondwe, Jenny M. MacLennan, Stephen J. Chapman, Malcolm E. Molyneux, Julian C. Knight, Chris C. A. Spencer, Thomas N. Williams, Calman A. MacLennan, J. Anthony G. Scott, Adrian V. S. Hill
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
Nontyphoidal Salmonella (NTS) is a major cause of bacteraemia in children and HIV-infected adults in Africa. Here, Gilchrist et al. conduct a genome-wide association study and show that genetic variation in STAT4 is a determinant of NTS in Kenyan and
Externí odkaz:
https://doaj.org/article/f39fdec2fbbb4ab0bac55463ac8b21f7
Autor:
Edna M. Ondari, Elizabeth J. Klemm, Chisomo L. Msefula, Moataz Abd El Ghany, Jennifer N. Heath, Derek J. Pickard, Lars Barquist, Gordon Dougan, Robert A. Kingsley, Calman A. MacLennan
Publikováno v:
Wellcome Open Research, Vol 4 (2019)
Background: Salmonella Typhimurium ST313 exhibits signatures of adaptation to invasive human infection, including higher resistance to humoral immune responses than gastrointestinal isolates. Full resistance to antibody-mediated complement killing (s
Externí odkaz:
https://doaj.org/article/e76cf5de64bc47299dbe1bae4d6deefa
Autor:
Nicholas A. Feasey, Amy K. Cain, Chisomo L. Msefula, Derek Pickard, Maaike Alaerts, Martin Aslett, Dean B. Everett, Theresa J. Allain, Gordon Dougan, Melita A. Gordon, Robert S. Heyderman, Robert A. Kingsley
Publikováno v:
Emerging Infectious Diseases, Vol 20, Iss 11, Pp 1957-1959 (2014)
Externí odkaz:
https://doaj.org/article/5a61cb6148f146e98fca19cb81880b31
Autor:
Larissa A. Singletary, Joyce E. Karlinsey, Stephen J. Libby, Jason P. Mooney, Kristen L. Lokken, Renée M. Tsolis, Mariana X. Byndloss, Lauren A. Hirao, Christopher A. Gaulke, Robert W. Crawford, Satya Dandekar, Robert A. Kingsley, Chisomo L. Msefula, Robert S. Heyderman, Ferric C. Fang
Publikováno v:
mBio, Vol 7, Iss 2 (2016)
ABSTRACT Nontyphoidal Salmonella enterica serovar Typhimurium is a frequent cause of bloodstream infections in children and HIV-infected adults in sub-Saharan Africa. Most isolates from African patients with bacteremia belong to a single sequence typ
Externí odkaz:
https://doaj.org/article/18c0318f4ce24989a9672270a4aff640
Autor:
Jonathan J Waluza, Robert S. Heyderman, Chisomo L. Msefula, Angeziwa Chirambo, Thomas Edwards, Nicholas A. Feasey, Melita A. Gordon, Jonathan M. Read, Eric Borgstein, Dalitso Zeka, Peter J. Diggle, Emma Thomson, Franziska Olgemoeller, Jillian S Gauld
Publikováno v:
Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
Background Typhoid fever remains a major source of morbidity and mortality in low-income settings. Its most feared complication is intestinal perforation. However, due to the paucity of diagnostic facilities in typhoid-endemic settings, including mic
Autor:
Yohane Diness, Chisomo L. Msefula, Nicola Elviss, Jonathan Rigby, Charity Mkwanda, Rory Miles, Rob Johnston, Ezzeddine Elmerhebi, Satheesh Nair, Heather Galloway, Jillian S Gauld, Katalina Tonthola, Marc Henrion, Thomas Edwards, Nicholas A. Feasey
Publikováno v:
Journal of applied microbiologyREFERENCES. 132(2)
Aims This study evaluated detection methods for Salmonella Typhi (S. Typhi) in the environment, to establish a novel pathway from field sampling to isolation of viable organisms and molecular confirmation from complex environmental samples, thus enab
Autor:
Angeziwa Chirambo, Ndaru Jambo, Marc Henrion, Melita A. Gordon, Robert S. Heyderman, Chisomo L. Msefula, Wilson Mandala, Arox W. Kamng’ona, Sandra Molina, Tonney S. Nyirenda, Miren Iturizza-Gomara
Publikováno v:
Wellcome Open Research
Background: The relationship between asymptomatic Salmonella exposure within the gastrointestinal tract and Salmonella bacteraemia is poorly understood, in part due to the low sensitivity of stool culture and the lack of validated molecular diagnosti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80662f5f31d33cc2e856fb78c7ddf15e
http://livrepository.liverpool.ac.uk/3123967/1/7db6c335-c5bf-4660-87b6-155401e39e01_16305_-_angeziwa_chirambo_v2(1).pdf
http://livrepository.liverpool.ac.uk/3123967/1/7db6c335-c5bf-4660-87b6-155401e39e01_16305_-_angeziwa_chirambo_v2(1).pdf