Dextrin conjugation to colistin inhibits its toxicity, cellular uptake and acute kidney injury in vivo .

Autor: Varache M; Advanced Therapies Group, School of Dentistry, College of Biomedical and Life Sciences, Cardiff University Heath Park Cardiff CF14 4XY UK FergusonEL@cardiff.ac.uk., Rizzo S; Advanced Therapies Group, School of Dentistry, College of Biomedical and Life Sciences, Cardiff University Heath Park Cardiff CF14 4XY UK FergusonEL@cardiff.ac.uk., Sayers EJ; School of Pharmacy and Pharmaceutical Sciences, Cardiff University CF10 3NB UK., Newbury L; Wales Kidney Research Unit, Division of Infection and Immunity, School of Medicine, College of Biomedical and Life Sciences, Cardiff University Cardiff CF14 4XN UK., Mason A; Wales Kidney Research Unit, Division of Infection and Immunity, School of Medicine, College of Biomedical and Life Sciences, Cardiff University Cardiff CF14 4XN UK., Liao CT; Systems Immunity Research Institute, Division of Infection and Immunity, School of Medicine, Cardiff University Cardiff CF14 4XN UK., Chiron E; Advanced Therapies Group, School of Dentistry, College of Biomedical and Life Sciences, Cardiff University Heath Park Cardiff CF14 4XY UK FergusonEL@cardiff.ac.uk., Bourdiec N; Advanced Therapies Group, School of Dentistry, College of Biomedical and Life Sciences, Cardiff University Heath Park Cardiff CF14 4XY UK FergusonEL@cardiff.ac.uk., Jones A; Advanced Therapies Group, School of Dentistry, College of Biomedical and Life Sciences, Cardiff University Heath Park Cardiff CF14 4XY UK FergusonEL@cardiff.ac.uk.; Cellular Pathology Department, University Dental Hospital, Cardiff and Vale University Health Board Cardiff CF14 4XY UK., Fraser DJ; Wales Kidney Research Unit, Division of Infection and Immunity, School of Medicine, College of Biomedical and Life Sciences, Cardiff University Cardiff CF14 4XN UK., Taylor PR; Systems Immunity Research Institute, Division of Infection and Immunity, School of Medicine, Cardiff University Cardiff CF14 4XN UK.; UK Dementia Research Institute at Cardiff Hadyn Ellis Building Maindy Road Cardiff CF24 4HQ UK., Jones AT; School of Pharmacy and Pharmaceutical Sciences, Cardiff University CF10 3NB UK., Thomas DW; Advanced Therapies Group, School of Dentistry, College of Biomedical and Life Sciences, Cardiff University Heath Park Cardiff CF14 4XY UK FergusonEL@cardiff.ac.uk.; Systems Immunity Research Institute, Division of Infection and Immunity, School of Medicine, Cardiff University Cardiff CF14 4XN UK., Ferguson EL; Advanced Therapies Group, School of Dentistry, College of Biomedical and Life Sciences, Cardiff University Heath Park Cardiff CF14 4XY UK FergusonEL@cardiff.ac.uk.

Publikováno v: RSC pharmaceutics [RSC Pharm] 2024 Feb 05; Vol. 1 (1), pp. 68-79. Date of Electronic Publication: 2024 Feb 05 (Print Publication: 2024).