Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Chirattikan Maicheen"'
Autor:
Chirattikan Maicheen, Chokchaloemwat Churnthammakarn, Nichapat Pongsroypech, Thitiphong Khamkhenshorngphanuch, Jiraporn Ungwitayatorn, Kanin Rangsangthong, Rathapon Asasutjarit, Sewan Theeramunkong
Publikováno v:
Molecules, Vol 28, Iss 7, p 3129 (2023)
Chromones are the structural building blocks of several natural flavonoids. The synthesis of chromones, which contain a hydroxy group on the ring, presents some challenges. We used the one-pot method to synthesize ten chromone derivatives and two rel
Externí odkaz:
https://doaj.org/article/dab6e4daf69646e6a9153b63f58bb37e
Autor:
Sewan Theeramunkong, Chirattikan Maicheen, Rinnara Krongsil, Waritsara Chaichanasap, Rathapon Asasutjarit, Opa Vajragupta
Publikováno v:
Chemical Papers. 76:3971-3985
Publikováno v:
Medicinal Chemistry Research. 26:662-671
A series of chromone derivatives have been evaluated as potential cyclooxygenase-2 (COX-2) inhibitors. The four most potent compounds, 48, 41, 39, and 35 displayed IC50 values of 3.30, 6.86, 7.36 and 7.46 µM, respectively. Compounds 35 and 38 showed
Publikováno v:
Bioorganic Chemistry. 57:142-147
Increasing parasite resistance to nearly all available antimalarial drugs becomes a serious problem to human health and necessitates the need to continue the search for new effective drugs. Recent studies have shown that clinically utilized HIV-1 pro
Publikováno v:
ScienceAsia. 45:221
Publikováno v:
Medicinal chemistry (Shariqah (United Arab Emirates)). 9(3)
A series of chromone derivatives were designed as potential topoisomerase I (Top I) inhibitors based on the docking simulation study. Sixteen synthesized compounds were evaluated for Top I inhibitory activity and some compounds were further tested fo