Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Chira Malmström"'
Autor:
Anne Juppo, Sirpa Laakso, Piritta Koistinen, DS Samiulla, Anna Shevchenko, Chira Malmström, Bert van Veen, Krista Ojala, Jukka Salmia, Timo Korjamo, Indu Bansal, Johanna Ylikotila
Publikováno v:
International journal of pharmaceutics. 606
Our objectives were to stabilize a non-clinical suspension for use in toxicological studies and to develop methods to investigate the stability of the formulation in terms of salt disproportionation. The compound under research was a hydrochloride sa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::690f44050c23756a7c4667aafae87a68
https://pubmed.ncbi.nlm.nih.gov/34273425
https://pubmed.ncbi.nlm.nih.gov/34273425
Autor:
Päivi Taavitsainen, Michael Niehues, Olaf Prien, Hille Gieschen, Mikko Koskinen, Chira Malmström, Steffen Sandmann, Timo Korjamo, Wiebke Janssen, Marja Kähkönen
Publikováno v:
Xenobiotica; the fate of foreign compounds in biological systems. 50(8)
1. Darolutamide is a novel selective androgen receptor antagonist consisting of two pharmacologically equipotent diastereoisomers. The absorption, distribution, metabolism and excretion properties of darolutamide in rats are reported.2. Non- or [
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc07f906daf87c912ef246192fe07225
https://pubmed.ncbi.nlm.nih.gov/32003293
https://pubmed.ncbi.nlm.nih.gov/32003293
Autor:
Passiniemi Mikko, Gerd Wohlfahrt, Petteri Rummakko, Reetta Riikonen, Riikka Huhtaniemi, Pekka Kallio, Päivi Taavitsainen, Karjalainen Arja, Chira Malmström, Hanna-Maija Metsänkylä, Meri Ramela, Riikka Oksala, Anu Moilanen, Mika Mustonen
Publikováno v:
The Journal of Steroid Biochemistry and Molecular Biology. 192:105115
We report the discovery of a novel nonsteroidal dual-action compound, ODM-204, that holds promise for treating patients with castration-resistant prostate cancer (CRPC), an advanced form of prostate cancer characterised by high androgen receptor (AR)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90e1dd9dd4e56ddc4b7cbcd89a7b7e4e
https://doi.org/10.1016/j.jsbmb.2018.02.004
https://doi.org/10.1016/j.jsbmb.2018.02.004
Publikováno v:
Chemosphere. 77:1514-1519
Neoplasia and other histopathological lesions in flounder (Platichthys flesus) liver have been investigated in several European sea areas, including the Baltic Sea. Several studies have been able to link neoplasm epizootics in fish with the exposure
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd19a9217e8cfccfbcdea6bd224b6a52
https://doi.org/10.1016/j.chemosphere.2009.09.055
https://doi.org/10.1016/j.chemosphere.2009.09.055
Autor:
Reetta Riikonen, Pekka Kallio, Riikka Oksala, Chira Malmström, Petteri Rummakko, Anu Moilanen, Mika Mustonen
Publikováno v:
Journal of Clinical Oncology. 34:230-230
230 Background: Castration-resistant prostate cancer (CRPC) is characterized by high androgen receptor (AR) expression and persistent activation of AR signaling axis by residual tissue androgens. Inhibiting AR and androgen biosynthesis together may b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::031d8b96f2e2f39bab5e3ba4c6bb165c
https://doi.org/10.1200/jco.2016.34.2_suppl.230
https://doi.org/10.1200/jco.2016.34.2_suppl.230
Autor:
Chira Malmström, Christiane Otto, Rolf Bohlmann, Iris Fuchs, Gilda Schwarz, Thua Österman, Mario Klewer, Richardus Vonk, Katja Prelle, Karl-Heinrich Fritzemeier, Duy Nguyen, Ludwig Zorn, Helga Altmann
Publikováno v:
The Journal of steroid biochemistry and molecular biology. 111(1-2)
Estrogen receptor (ER) ligands that are able to prevent postmenopausal bone loss, but have reduced activity in the uterus and the mammary gland might be of great value for hormone therapy. It is well established that the classical ER can activate gen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c70dcbff0a4e3c97b826824e686b7af
https://pubmed.ncbi.nlm.nih.gov/18606537
https://pubmed.ncbi.nlm.nih.gov/18606537