The involvement of language-associated networks, tracts, and cortical regions in frontotemporal dementia and amyotrophic lateral sclerosis: Structural and functional alterations.

Autor: Tahedl M; Computational Neuroimaging Group (CNG), School of Medicine, Trinity College Dublin, Dublin, Ireland., Tan EL; Computational Neuroimaging Group (CNG), School of Medicine, Trinity College Dublin, Dublin, Ireland., Chipika RH; Computational Neuroimaging Group (CNG), School of Medicine, Trinity College Dublin, Dublin, Ireland., Lope J; Computational Neuroimaging Group (CNG), School of Medicine, Trinity College Dublin, Dublin, Ireland., Hengeveld JC; Smurfit Institute of Genetics, Trinity College Dublin, Dublin, Ireland., Doherty MA; Smurfit Institute of Genetics, Trinity College Dublin, Dublin, Ireland., McLaughlin RL; Smurfit Institute of Genetics, Trinity College Dublin, Dublin, Ireland., Hardiman O; Computational Neuroimaging Group (CNG), School of Medicine, Trinity College Dublin, Dublin, Ireland., Hutchinson S; Department of Neurology, St James's Hospital, Dublin, Ireland., McKenna MC; Computational Neuroimaging Group (CNG), School of Medicine, Trinity College Dublin, Dublin, Ireland.; Department of Neurology, St James's Hospital, Dublin, Ireland., Bede P; Computational Neuroimaging Group (CNG), School of Medicine, Trinity College Dublin, Dublin, Ireland.; Department of Neurology, St James's Hospital, Dublin, Ireland.

Publikováno v: Brain and behavior [Brain Behav] 2023 Nov; Vol. 13 (11), pp. e3250. Date of Electronic Publication: 2023 Sep 11.

Brainstem-cortex disconnection in amyotrophic lateral sclerosis: bulbar impairment, genotype associations, asymptomatic changes and biomarker opportunities.

Autor: Tahedl M; Computational Neuroimaging Group (CNG), Trinity Biomedical Sciences Institute, Trinity College Dublin, Room 5.43, Pearse Street, Dublin 2, Dublin, Ireland., Tan EL; Computational Neuroimaging Group (CNG), Trinity Biomedical Sciences Institute, Trinity College Dublin, Room 5.43, Pearse Street, Dublin 2, Dublin, Ireland., Chipika RH; Computational Neuroimaging Group (CNG), Trinity Biomedical Sciences Institute, Trinity College Dublin, Room 5.43, Pearse Street, Dublin 2, Dublin, Ireland., Hengeveld JC; Smurfit Institute of Genetics, Trinity College Dublin, Dublin, Ireland., Vajda A; Smurfit Institute of Genetics, Trinity College Dublin, Dublin, Ireland., Doherty MA; Smurfit Institute of Genetics, Trinity College Dublin, Dublin, Ireland., McLaughlin RL; Smurfit Institute of Genetics, Trinity College Dublin, Dublin, Ireland., Siah WF; Computational Neuroimaging Group (CNG), Trinity Biomedical Sciences Institute, Trinity College Dublin, Room 5.43, Pearse Street, Dublin 2, Dublin, Ireland., Hardiman O; Computational Neuroimaging Group (CNG), Trinity Biomedical Sciences Institute, Trinity College Dublin, Room 5.43, Pearse Street, Dublin 2, Dublin, Ireland., Bede P; Computational Neuroimaging Group (CNG), Trinity Biomedical Sciences Institute, Trinity College Dublin, Room 5.43, Pearse Street, Dublin 2, Dublin, Ireland. bedep@tcd.ie.; Department of Neurology, St James's Hospital, Dublin, Ireland. bedep@tcd.ie.

Publikováno v: Journal of neurology [J Neurol] 2023 Jul; Vol. 270 (7), pp. 3511-3526. Date of Electronic Publication: 2023 Apr 06.

Cerebellar degeneration in primary lateral sclerosis: an under-recognized facet of PLS.

Autor: Finegan E; Computational Neuroimaging Group, Biomedical Sciences Institute, Trinity College Dublin, Dublin, Ireland., Siah WF; Computational Neuroimaging Group, Biomedical Sciences Institute, Trinity College Dublin, Dublin, Ireland., Li Hi Shing S; Computational Neuroimaging Group, Biomedical Sciences Institute, Trinity College Dublin, Dublin, Ireland., Chipika RH; Computational Neuroimaging Group, Biomedical Sciences Institute, Trinity College Dublin, Dublin, Ireland., Hardiman O; Computational Neuroimaging Group, Biomedical Sciences Institute, Trinity College Dublin, Dublin, Ireland., Bede P; Computational Neuroimaging Group, Biomedical Sciences Institute, Trinity College Dublin, Dublin, Ireland.; Department of Neurology, St James's Hospital Dublin, Dublin, Ireland.

Publikováno v: Amyotrophic lateral sclerosis & frontotemporal degeneration [Amyotroph Lateral Scler Frontotemporal Degener] 2022 Nov; Vol. 23 (7-8), pp. 542-553. Date of Electronic Publication: 2022 Jan 06.

Mapping cortical disease-burden at individual-level in frontotemporal dementia: implications for clinical care and pharmacological trials.

Autor: McKenna MC; Computational Neuroimaging Group, Biomedical Sciences Institute, Trinity College Dublin, Dublin, Ireland., Tahedl M; Computational Neuroimaging Group, Biomedical Sciences Institute, Trinity College Dublin, Dublin, Ireland.; Department of Psychiatry and Psychotherapy, University of Regensburg, Regensburg, Germany.; Institute for Psychology, University of Regensburg, Regensburg, Germany., Lope J; Computational Neuroimaging Group, Biomedical Sciences Institute, Trinity College Dublin, Dublin, Ireland., Chipika RH; Computational Neuroimaging Group, Biomedical Sciences Institute, Trinity College Dublin, Dublin, Ireland., Li Hi Shing S; Computational Neuroimaging Group, Biomedical Sciences Institute, Trinity College Dublin, Dublin, Ireland., Doherty MA; Complex Trait Genomics Laboratory, Smurfit Institute of Genetics, Trinity College Dublin, Dublin, Ireland., Hengeveld JC; Complex Trait Genomics Laboratory, Smurfit Institute of Genetics, Trinity College Dublin, Dublin, Ireland., Vajda A; Complex Trait Genomics Laboratory, Smurfit Institute of Genetics, Trinity College Dublin, Dublin, Ireland., McLaughlin RL; Complex Trait Genomics Laboratory, Smurfit Institute of Genetics, Trinity College Dublin, Dublin, Ireland., Hardiman O; Computational Neuroimaging Group, Biomedical Sciences Institute, Trinity College Dublin, Dublin, Ireland., Hutchinson S; Department of Neurology, St James's Hospital, Dublin, Ireland., Bede P; Computational Neuroimaging Group, Biomedical Sciences Institute, Trinity College Dublin, Dublin, Ireland. bedep@tcd.ie.

Publikováno v: Brain imaging and behavior [Brain Imaging Behav] 2022 Jun; Vol. 16 (3), pp. 1196-1207. Date of Electronic Publication: 2021 Dec 09.

Phenotypic categorisation of individual subjects with motor neuron disease based on radiological disease burden patterns: A machine-learning approach.

Autor: Bede P; Computational Neuroimaging Group, Biomedical Sciences Institute, Trinity College Dublin, Ireland; Pitié-Salpêtrière University Hospital, Sorbonne University, Paris, France. Electronic address: bedep@tcd.ie., Murad A; Computational Neuroimaging Group, Biomedical Sciences Institute, Trinity College Dublin, Ireland., Lope J; Computational Neuroimaging Group, Biomedical Sciences Institute, Trinity College Dublin, Ireland., Li Hi Shing S; Computational Neuroimaging Group, Biomedical Sciences Institute, Trinity College Dublin, Ireland., Finegan E; Computational Neuroimaging Group, Biomedical Sciences Institute, Trinity College Dublin, Ireland., Chipika RH; Computational Neuroimaging Group, Biomedical Sciences Institute, Trinity College Dublin, Ireland., Hardiman O; Computational Neuroimaging Group, Biomedical Sciences Institute, Trinity College Dublin, Ireland., Chang KM; Computational Neuroimaging Group, Biomedical Sciences Institute, Trinity College Dublin, Ireland; Department of Electronics and Computer Science, University of Southampton, UK.

Publikováno v: Journal of the neurological sciences [J Neurol Sci] 2022 Jan 15; Vol. 432, pp. 120079. Date of Electronic Publication: 2021 Dec 02.