Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Chip McGuirt"'
Autor:
Linda Sutton, Edgardo Rivera, Chip McGuirt, Mark L. Graham, Bruce Colwell, Gabriel N. Hortobagyi, Heather S. Conklin, Debra Frye, Matt Somerville, Jeremey Levin
Publikováno v:
Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 20(4)
PURPOSE: Eniluracil (776C85), a potent inactivator of dihydropyrimidine dehydrogenase, allows fluorouracil (5-FU) to be administered orally on a schedule that simulates continuous-infusion 5-FU. The primary objective of this study was to estimate the
Autor:
Howard Hochster, Jacob Lokich, Charles H. Weaver, William N. Bell, John A. Hohneker, Mark A. O’Rourke, Eric M. Chevlen, Chip McGuirt, Richard L. Schilsky, Sridhar Mani, Robin L. White, Thomas L. Beck, Jeremey Levin
Publikováno v:
Scopus-Elsevier
Europe PubMed Central
Europe PubMed Central
PURPOSE: To determine the efficacy of fluorouracil (5-FU) plus eniluracil when administered to patients with previously untreated metastatic colorectal cancer. PATIENTS AND METHODS: In this single-arm phase II study, patients with previously untreate