Epigenomic biomarkers insights in PBMCs for prognostic assessment of ECMO-treated cardiogenic shock patients

Autor: Yi-Jing Hsiao, Su-Chien Chiang, Chih-Hsien Wang, Nai-Hsin Chi, Hsi-Yu Yu, Tsai-Hsia Hong, Hsuan-Yu Chen, Chien-Yu Lin, Shuenn-Wen Kuo, Kang-Yi Su, Wen-Je Ko, Li-Ming Hsu, Chih-An Lin, Chiou-Ling Cheng, Yan-Ming Chen, Yih-Sharng Chen, Sung-Liang Yu

Publikováno v: Clinical Epigenetics, Vol 16, Iss 1, Pp 1-14 (2024)

Abstract Objective As the global use of extracorporeal membrane oxygenation (ECMO) treatment increases, survival rates have not correspondingly improved, emphasizing the need for refined patient selection to optimize resource allocation. Currently, p

Externí odkaz: https://doaj.org/article/57c3ed14071a4272b5c84ba0c00d414b

Genome-Wide Epigenetic Landscape of Lung Adenocarcinoma Links HOXB9 DNA Methylation to Intrinsic EGFR-TKI Resistance and Heterogeneous Responses

Autor: Chiou-Ling Cheng, Huei-Wen Chen, Tsung-Ying Yang, Ker-Chau Li, Gee-Chen Chang, Sheng-Fang Su, Jeng-Sen Tseng, Chia Hsin Liu, Sung-Liang Yu, Kuo-Hsuan Hsu, Chao-Chi Ho, Kun-Chieh Chen

Publikováno v: JCO Precision Oncology

PURPOSE Epidermal growth factor receptor (EGFR)-tyrosine kinase inhibitors (TKIs) show efficacy in treating patients with lung adenocarcinoma with EGFR-activating mutations. However, a significant subset of targeted patients fail to respond. Unlike a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec88c6dc63d1b62b1889143e302f8cd3
https://pubmed.ncbi.nlm.nih.gov/34036228

Clustered Genomic Alterations in Chromosome 7p Dictate Outcomes and Targeted Treatment Responses of Lung Adenocarcinoma With EGFR-Activating Mutations

Autor: Shinsheng Yuan, Jin-Yuan Shih, Tai Ching Lin, Yi Chiung Hsu, Ker-Chau Li, Tsung Ying Yang, Huei-Wen Chen, Gee-Chen Chang, Kuo-Hsuan Hsu, Kang-Yi Su, Chung Ping Hsu, Kang Chung Yang, Yih-Leong Chang, Pan-Chyr Yang, Jiun Yi Hsia, Chiou Ling Cheng, Hsuan-Yu Chen, Chu Chun Hsu, Sung-Liang Yu, Chien-Yu Lin, Jeremy J.W. Chen, Yi Wei Chen, Chin Di Wang, Guani Wu, Chih Yi Chen, Chong-Jen Yu, Kun Cheieh Chen, Yi Ling Lai, Chia Hsin Liu

Publikováno v: Journal of Clinical Oncology. 29:3435-3442

Purpose Although epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) have been proven more effective for patients with lung adenocarcinoma with EGFR-activating mutation rather than wild type, the former group still includes appr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6d18c063df3720f01b1505a92116f5f
https://doi.org/10.1200/jco.2011.35.3979

Epigenomic biomarkers insights in PBMCs for prognostic assessment of ECMO-treated cardiogenic shock patients.

Autor: Hsiao, Yi-Jing^1,2 (AUTHOR), Chiang, Su-Chien³ (AUTHOR), Wang, Chih-Hsien⁴ (AUTHOR), Chi, Nai-Hsin⁴ (AUTHOR), Yu, Hsi-Yu⁴ (AUTHOR), Hong, Tsai-Hsia⁵ (AUTHOR), Chen, Hsuan-Yu⁶ (AUTHOR), Lin, Chien-Yu⁶ (AUTHOR), Kuo, Shuenn-Wen⁴ (AUTHOR), Su, Kang-Yi^1,7 (AUTHOR), Ko, Wen-Je⁴ (AUTHOR), Hsu, Li-Ming⁴ (AUTHOR), Lin, Chih-An¹ (AUTHOR), Cheng, Chiou-Ling¹ (AUTHOR), Chen, Yan-Ming¹ (AUTHOR), Chen, Yih-Sharng⁴ (AUTHOR), Yu, Sung-Liang^1,7,8,9,10 (AUTHOR) slyu@ntu.edu.tw

Publikováno v: Clinical Epigenetics. 10/3/2024, Vol. 16 Issue 1, p1-14. 14p.

Abstract 3075: miRNA-10a* enhances invasiveness via suppression of HDAC5 in lung cancer

Autor: Chiou-Ling Cheng, Pin-Yen Hsu, Sung-Liang Yu, Bing-Ching Ho, Guan-Tarn Huang, Hsuan-Yu Chen

Publikováno v: Cancer Research. 75:3075-3075

Non-small cell lung cancer (NSCLC) is the leading cause of cancer death worldwide. Metastasis, the spread process of cancer cells from a primary tumor to seed secondary tumors in distant sites, is one of the big challenges in cancer treatment today.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3415793b661ee7b400de4bfa59c8ea5a
https://doi.org/10.1158/1538-7445.am2015-3075