Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Chintan Chheda"'
Autor:
Ce Li, Susan Morvaridi, Gloria Lam, Chintan Chheda, Yoshiko Kamata, Makoto Katsumata, Mouad Edderkaoui, Xiaopu Yuan, Nicholas Nissen, Stephen J. Pandol, Qiang Wang
Publikováno v:
Frontiers in Physiology, Vol 10 (2019)
Pancreatic ductal adenocarcinoma (PDAC) is among the deadliest epithelial malignancies and remains difficult to treat. Pancreatic intraepithelial neoplasias (PanINs) represent the majority of the pre-cancer lesions in the pancreas. The PDAC microenvi
Externí odkaz:
https://doaj.org/article/08ac7a0846e84d339405402b25421afc
Autor:
Jingzhen Yuan, Burcu Hasdemir, Tanya Tan, Chintan Chheda, Jean Rivier, Stephen J Pandol, Aditi Bhargava
Publikováno v:
PLoS ONE, Vol 14, Iss 5, p e0217065 (2019)
Because little is known about the role of corticotropin-releasing factor (CRF) agonists in regulating responses in pancreatitis, we evaluated the effects of urocortin 2 (UCN2) and stressin1 in caerulein-induced acute pancreatitis (AP) model in rats.
Externí odkaz:
https://doaj.org/article/7d6edc5ca6704b4ab4ee7f3796e459f6
Publikováno v:
Frontiers in Physiology, Vol 8 (2017)
Nuclear factor-kappa B (NF-κB) activation is a key early signal regulating inflammatory and cell death responses in acute pancreatitis. Our previous in vitro studies with molecular approaches on AR42J cell showed that protein kinase D (PKD/PKD1) act
Externí odkaz:
https://doaj.org/article/73ae5a0ce669423d9dcb39ae4a2e6836
Autor:
Hung Pham, Chiara Birtolo, Chintan Chheda, Wendy Yang, Maria Rodriguez, Sandy Liu, Gabriele Gugliotta, Michael Lewis, Vincenzo Cirulli, Stephen Pandol, Andrzej Ptasznik
Publikováno v:
Frontiers in Physiology, Vol 7 (2016)
Fibrotic disorders involve replacement of normal parenchyma with myofibroblasts, which deposit connective tissue, leading to obliteration of the function of the underlying organ. The treatment options are inadequate and reflect the fact that signalin
Externí odkaz:
https://doaj.org/article/8a7230bd9955468b915e3a83c65745c7
Autor:
Jiyong Yang, Chintan Chheda, Adrian Lim, Dina Hauptschein, Latifa Zayou, Josiah Tang, Stephen J. Pandol, Mouad Edderkaoui
Publikováno v:
Pancreas
OBJECTIVES: Cigarette smoking is an established risk factor for pancreatic ductal adenocarcinoma (PDAC). In this project we investigated the effect of smoking and the role of histone deacetylase 4 (HDAC4) in PDAC invasion and metastasis. METHODS: Cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f53ee552b2872e2ebe5708308f11c9b4
https://doi.org/10.1097/mpa.0000000000001998
https://doi.org/10.1097/mpa.0000000000001998
Publikováno v:
Biochim Biophys Acta Mol Basis Dis
BACKGROUND: Alcohol abuse, a main cause of pancreatitis, has been known to augment NF-κB activation and cell necrosis in pancreatitis. However, the underlying mechanisms are unclear. We recently reported that inhibition of protein kinase D (PKD) all
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5eb436dae000aa445af038704f33e80
https://pubmed.ncbi.nlm.nih.gov/35835415
https://pubmed.ncbi.nlm.nih.gov/35835415
Publikováno v:
Gastroenterology. 162:S-1072
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::74148b4c7da54ff0da3acb6e885b76bf
https://doi.org/10.1016/s0016-5085(22)62568-x
https://doi.org/10.1016/s0016-5085(22)62568-x
Publikováno v:
2020 IEEE International Conference for Innovation in Technology (INOCON).
Autism is a syndrome which has been on the increase in recent years. There are different systems and applications that have been developed for helping in monitoring autistic characteristics which have used different methods. This paper aims at increa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::849524d133ad4c34bd1dc326afd74258
https://doi.org/10.1109/inocon50539.2020.9298336
https://doi.org/10.1109/inocon50539.2020.9298336
Autor:
Reetu Thakur, Meng Geng, Stephen J. Pandol, Jingzhen Yuan, Chintan Chheda, Honit Piplani, Grace Tan
Publikováno v:
Biochim Biophys Acta Mol Basis Dis
Background Protein kinase D (PKD) family, which includes PKD/PKD1, PKD2, and PKD3, has been increasingly implicated in the regulation of multiple cellular functions and human diseases. We recently reported that pharmacologic inhibition of PKD amelior
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7f261935c965fc148fa2d579b676fdd
https://pubmed.ncbi.nlm.nih.gov/33039594
https://pubmed.ncbi.nlm.nih.gov/33039594
Autor:
Adrian Lim, Stephen J. Pandol, Chintan Chheda, Omer H. Elmadbouh, Mouad Edderkaoui, Fouzia Zayou
Publikováno v:
Cancer Research. 81:2403-2403
Background: Resistance of pancreatic ductal adenocarcinoma (PDAC) to current treatment regimens contributes to the dismal prognosis for patients diagnosed with the disease. Accumulated evidence indicates that metabolic alterations may play a role in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::76e9d5c3fa984e763ba53f80446b3920
https://doi.org/10.1158/1538-7445.am2021-2403
https://doi.org/10.1158/1538-7445.am2021-2403