Zobrazeno 1 - 10
of 106
pro vyhledávání: '"Chinpan Chen"'
Autor:
Sarita Aryal, Hong-Ming Hsu, Yuan-Chao Lou, Chien-Hsin Chu, Jung-Hsiang Tai, Chun-Hua Hsu, Chinpan Chen
Publikováno v:
Biomolecules, Vol 10, Iss 9, p 1239 (2020)
In Trichomonas vaginalis (T. vaginalis), cyclophilins play a vital role in dislodging Myb proteins from the membrane compartment and leading them to nuclear translocation. We previously reported that TvCyP1 cyclophilin from T. vaginalis forms a dimer
Externí odkaz:
https://doaj.org/article/4e8c2d4057f7446e93123004e96cad56
Autor:
Ting-Wei Chang, Shu-Yi Wei, Shih-Han Wang, Hung-Mu Wei, Yu-June Wang, Chiu-Feng Wang, Chinpan Chen, You-Di Liao
Publikováno v:
PLoS ONE, Vol 12, Iss 10, p e0186442 (2017)
Antimicrobial peptides are important components of the host innate defense mechanism against invading pathogens, especially for drug-resistant bacteria. In addition to bactericidal activity, the 25 residue peptide TP4 isolated from Nile tilapia also
Externí odkaz:
https://doaj.org/article/e0a3ed83a5284412b08c17d995a0eced
Publikováno v:
PLoS ONE, Vol 12, Iss 4, p e0175051 (2017)
Previously, we identified that both fingers 1 and 2 in the three Cys2His2 zinc-finger domains (TZD) of testis zinc-finger protein specifically bind to its cognate DNA; however, finger 3 is non-sequence-specific. To gain insights into the interaction
Externí odkaz:
https://doaj.org/article/2b024eb6d2664cc596ba223d664cd614
Autor:
Tien-Sheng Tseng, Shih-Han Wang, Ting-Wei Chang, Hung-Mu Wei, Yu-June Wang, Keng-Chang Tsai, You-Di Liao, Chinpan Chen
Publikováno v:
PLoS ONE, Vol 11, Iss 10, p e0164597 (2016)
The emergence of antibiotic-resistant microbial strains has become a public health issue and there is an urgent need to develop new anti-infective molecules. Although natural antimicrobial peptides (AMPs) can exert bactericidal activities, they have
Externí odkaz:
https://doaj.org/article/5423bcb03a154bc18402a5036f12cac3
Publikováno v:
PLoS ONE, Vol 6, Iss 9, p e25801 (2011)
BACKGROUND: Arylamine N-acetyltransferase 2 (NAT2) is an important catalytic enzyme that metabolizes the carcinogenic arylamines, hydrazine drugs and chemicals. This enzyme is highly polymorphic in different human populations. Several polymorphisms o
Externí odkaz:
https://doaj.org/article/0b79920264c54f598d97ef1f5ec6c43f
PmrA, an OmpR/PhoB-family response regulator, activates gene transcription responsible for polymyxin resistance in bacteria by recognizing promoters in which the canonical -35 element is replaced by the pmra-box, representing the PmrA recognition seq
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::baef02cbeac53d5b153ad702e69c1f13
https://doi.org/10.1101/2022.07.20.500760
https://doi.org/10.1101/2022.07.20.500760
Autor:
Jangam Vikram Kumar, Tien‐Sheng Tseng, Yuan‐Chao Lou, Shu‐Yi Wei, Tsung‐Han Wu, Hao‐Cheng Tang, Yi‐Chih Chiu, Chun‐Hua Hsu, Chinpan Chen
Publikováno v:
Protein Sci
In Staphylococcus aureus, vancomycin‐resistance‐associated response regulator (VraR) is a part of the VraSR two‐component system, which is responsible for activating a cell wall‐stress stimulon in response to an antibiotic that inhibits cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b69a8eeef2e73efde25c29dc90d3901
https://doi.org/10.1002/pro.4286
https://doi.org/10.1002/pro.4286
Autor:
Hong-Ming Hsu, Yu Hsin Huang, Shu Hui Chen, Sarita Aryal, Jung-Hsiang Tai, Chinpan Chen, Chien Hsin Chu, Hsing Wei Liu
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-18 (2020)
Scientific Reports
Scientific Reports
In Trichomonas vaginalis, the TvCyP1-catalyzed conformational switches of two glycinyl-prolyl imide bonds in Myb3 were previously shown to regulate the trafficking of Myb3 from cytoplasmic membrane compartments towards the nucleus. In this study, TvC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f55fc101354fca0fb76dc55e3e4432a9
http://link.springer.com/article/10.1038/s41598-020-58270-6
http://link.springer.com/article/10.1038/s41598-020-58270-6
Autor:
Chinpan Chen, Yuan-Chao Lou, Sushant Sadotra, Hsin‐Hong Yeh, Chun-Hua Hsu, Chun-Chi Chou, Chia‐Yu Chien
Publikováno v:
Proteins: Structure, Function, and Bioinformatics. 88:69-81
In class II transcription activation, the transcription factor normally binds to the promoter near the -35 position and contacts the domain 4 of σ factors (σ4 ) to activate transcription. However, σ4 of σ70 appears to be poorly folded on its own.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2a4aa78ed53156f0261c2d6473ebc78c
https://doi.org/10.1002/prot.25768
https://doi.org/10.1002/prot.25768
Publikováno v:
RSC Advances. 9:9308-9312
The PhoQ/PhoP two-component system regulates the physiological and virulence functions of Salmonella enterica. However, the mode of action of known PhoP inhibitors is unclear. We systematically constructed a pharmacophore model of inhibitors to probe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::27684144e4272b6e864499d4e03dc665
https://doi.org/10.1039/c9ra00620f
https://doi.org/10.1039/c9ra00620f