Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Chinnu Salim"'
Autor:
Mahesh Chandra Kodali, Chinnu Salim, Saifudeen Ismael, Sarah Grace Lebovitz, Geng Lin, Francesca-Fang Liao
Publikováno v:
Molecular Brain, Vol 17, Iss 1, Pp 1-8 (2024)
Abstract The mechanisms through which systemic inflammation exerts its effect on the central nervous system (CNS) are still not completely understood. Exosomes are small (30 to 100 nm) membrane-bound extracellular vesicles released by most of the mam
Externí odkaz:
https://doaj.org/article/db7753accaa44e4ab1921896e587f609
Publikováno v:
BMC Biology, Vol 22, Iss 1, Pp 1-17 (2024)
Abstract Background In all organisms, the innate immune system defends against pathogens through basal expression of molecules that provide critical barriers to invasion and inducible expression of effectors that combat infection. The adenosine deami
Externí odkaz:
https://doaj.org/article/a704ed3a390c4da78923190a8ad2a70a
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-18 (2022)
Abstract Despite the catastrophic consequences of alcohol abuse, alcohol use disorders (AUD) and comorbidities continue to strain the healthcare system, largely due to the effects of alcohol-seeking behavior. An improved understanding of the molecula
Externí odkaz:
https://doaj.org/article/ff45d7695b284ab79920c369f6a04423
Publikováno v:
Metabolites, Vol 13, Iss 1, p 62 (2022)
Persistent alcohol seeking despite the risk of aversive consequences is a crucial characteristic of alcohol use disorders (AUDs). Therefore, an improved understanding of the molecular basis of alcohol seeking despite aversive stimuli or punishment in
Externí odkaz:
https://doaj.org/article/b994a7e71b55464bafab4ba133262bbe
Publikováno v:
In Biomedicine & Pharmacotherapy September 2018 105:997-1005
BackgroundIn all organisms, the innate immune system defends against pathogens through basal expression of molecules that provide critical barriers to invasion and inducible expression of effectors that combat infection. The adenosine deaminase that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::38d6556cb8db32b7c006aaac660c1a0d
https://doi.org/10.1101/2023.05.03.539277
https://doi.org/10.1101/2023.05.03.539277
Identifying genetic variants associated with nicotine-motivated behavioral traits is an important strategy to understand the fundamental mechanisms underpinning smoking and tobacco abuse. For suitable emulation of behavioral phenotype with the full a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a2baa4ab27e0264e2479e8fbf178cd3a
https://doi.org/10.1101/2022.06.21.497113
https://doi.org/10.1101/2022.06.21.497113
An improved understanding of the molecular basis of alcohol seeking despite the catastrophic consequences of alcohol abuse is likely to enrich our treatments for Alcohol Use Disorders (AUD) and comorbidities. The compulsive seeking is characterized b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e851d7469490cee85b77239b16e4772d
https://doi.org/10.1101/2021.10.03.462755
https://doi.org/10.1101/2021.10.03.462755
Publikováno v:
Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology. 211:15-24
The higher susceptibility of high glucose fed C. elegans to Monocrotophos (MCP, an organophosphorus insecticide) - induced dopaminergic (DA) neuronal degeneration was recently demonstrated. Employing this acute exposure model, the impact of MCP on DA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbe353985388ec4a92ee1091d58003ba
https://doi.org/10.1016/j.cbpc.2018.05.002
https://doi.org/10.1016/j.cbpc.2018.05.002
Autor:
Chinnu Salim, P.S. Rajini
Publikováno v:
Journal of Applied Toxicology. 37:772-780
The present study aimed to obtain insights into the mechanism(s) by which glucose-rich diet aggravates monocrotophos (MCP)-induced dopaminergic neuronal dysfunction in Caenorhabditis elegans. In this study, we exposed three different strains of worms
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a081392231ddfad513a5bb7ad76e609c
https://doi.org/10.1002/jat.3426
https://doi.org/10.1002/jat.3426