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pro vyhledávání: '"Chinniah K. Arunagiri"'
Autor:
Melinda G. Lowe, Patrick W. Mobley, Ian Macreadie, Ahmed A. Azad, Chinniah K. Arunagiri, Cyril C. Curtain
Publikováno v:
AIDS Research and Human Retroviruses. 13:1213-1220
Myristoylated 21- and 25-residue N-terminal peptides of the Nef protein of HIV-1 lysed human erythrocytes and were cytotoxic toward a human CD4+ T cell line, CEM, and primary human peripheral blood mononuclear cells (PBMCs). The corresponding nonmyri
Publikováno v:
Molecular Microbiology. 19:1185-1192
Summary Vpr is a virion-associated protein of human immuno-deficiency virus type 1 (HIV-1) whose function in acquired immune deficiency syndrome (AIDS) has been uncertain. We previously employed yeast as a model to examine the effects of Vpr on basic
Publikováno v:
ResearcherID
We have previously shown that expression of HIV-1 vpr in yeast results in cell growth arrest and structural defects, and identified a C-terminal domain of Vpr as being responsible for these effects in yeast.1 In this report we show that recombinant V