Výsledky vyhledávání - "Chinniah K. Arunagiri"

Cytotoxic Activity of the Amino-Terminal Region of HIV Type 1 Nef Protein

Autor: Melinda G. Lowe, Patrick W. Mobley, Ian Macreadie, Ahmed A. Azad, Chinniah K. Arunagiri, Cyril C. Curtain

Publikováno v: AIDS Research and Human Retroviruses. 13:1213-1220

Myristoylated 21- and 25-residue N-terminal peptides of the Nef protein of HIV-1 lysed human erythrocytes and were cytotoxic toward a human CD4+ T cell line, CEM, and primary human peripheral blood mononuclear cells (PBMCs). The corresponding nonmyri

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98dc2117a05c1c63512ddea6be1400ac
https://doi.org/10.1089/aid.1997.13.1213

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Extracellular addition of a domain of HIV-1 Vpr containing the amino acid sequence motif H(S/F)RIG causes cell membrane permeabilization and death

Autor: Ian Macreadie, Jacinta F. White, Chinniah K. Arunagiri, Dean R. Hewish, Ahmed A. Azad

Publikováno v: Molecular Microbiology. 19:1185-1192

Summary Vpr is a virion-associated protein of human immuno-deficiency virus type 1 (HIV-1) whose function in acquired immune deficiency syndrome (AIDS) has been uncertain. We previously employed yeast as a model to examine the effects of Vpr on basic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5bf75fb8e34f707e7e1cade300773a27
https://doi.org/10.1111/j.1365-2958.1996.tb02464.x

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A C-terminal domain of HIV-1 accessory protein Vpr is involved in penetration, mitochondrial dysfunction and apoptosis of human CD4+ lymphocytes

Autor: Ian Macreadie, Dean R. Hewish, Chinniah K. Arunagiri, Ahmed A. Azad

Publikováno v: ResearcherID

We have previously shown that expression of HIV-1 vpr in yeast results in cell growth arrest and structural defects, and identified a C-terminal domain of Vpr as being responsible for these effects in yeast.1 In this report we show that recombinant V

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea582c53fe909c4c532fc0aa5df0c7bf
https://pubmed.ncbi.nlm.nih.gov/14646566

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Akademický článek

Extracellular addition of a domain of HIV-1 Vpr containing the amino acid sequence motif H(S/F)RIG causes cell membrane permeabilization and death.

Autor: Macreadie, Ian G., Arunagiri, Chinniah K., Hewish, Dean R., White, Jacinta F., Azad, A. A.

Publikováno v: Molecular Microbiology; Mar1996, Vol. 19 Issue 6, p1185-1192, 8p, 2 Color Photographs, 3 Graphs

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