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Autor:
Widdrington, JD, Gomez-Duran, A, Steyn, JS, Pyle, A, Ruchaud-Sparagano, M-H, Scott, J, Baudouin, SV, Rostron, AJ, Simpson, J, Chinnery FMedSci, PF
Monocytes from sepsis patients have mitochondrial DNA (mtDNA) depletion and immune deactivation. Here we find that THP-1 cell immune responses are impaired by experimentally depleting mtDNA, through dysregulated immune signalling, and rescued by inte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03274b52a3e6bafd1b4e916d8eae7f5b