Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Chinnaswamy, Kasinathan"'
Publikováno v:
Neurochemical Research. 40:2167-2176
Fmr1 and FMRP underlie Fragile X Syndrome (FXS) and are linked with related autism spectrum disorders (ASD). Fmr1 also has an essential role in eye and lens development. Lenses express FMRP along with γ-aminobutyric acid (GABA) receptors (GABARs), p
Autor:
Amariliz Rivera-Medina, Scott C. Kachlany, Vanessa Espinosa, Vahid Rahimian, Anukriti Gupta, Chinnaswamy Kasinathan, Eugenio Capitle, Katie Miro, Helen A. Aguila, Lindsey E. Galusha
Publikováno v:
Journal of Leukocyte Biology. 97:439-446
Allergic asthma is a chronic respiratory disease that results from an exaggerated inflammatory response in the airways. Environment stimuli, such as pollen and HDM, cause activation and migration of inflammatory WBCs into the respiratory tract, where
Publikováno v:
Neurochemical research. 42(4)
There is a second cell type in your body that expresses scores of the most intensively studied genes in neuroscience and exclusively shares critical interdependent modes of molecular regulation that include a network first described as responsible fo
Autor:
Rajesh H. Kaswala, William L. Klein, Chinnaswamy Kasinathan, Peter H. Frederikse, Claudine L. Bitel
Publikováno v:
Journal of Alzheimer's Disease. 32:291-305
Alzheimer's disease (AD) is the major age-dependent disease of the brain, but what instigates late-onset AD is not yet clear. Epidemiological, animal model, and cell biology findings suggest links between AD and diabetes. Although AD pathology is acc
Publikováno v:
International Journal of Peptide Research and Therapeutics. 18:99-106
Alzheimer's Disease (AD), a debilitating neurodegenerative disease is caused by aggregation and accumulation of a 39-43 amino acid peptide (amyloid β or Aβ) in brain parenchyma and cerebrovasculature. The rational approach would be to use drugs tha
Publikováno v:
Current Alzheimer Research. 5:26-32
Alzheimers Disease (AD) is caused by the deposition of insoluble and toxic amyloid peptides (Aβ) in the brain leading to memory loss and other associated neurodegenerative symptoms. To date there is limited treatment options and strategies for treat
Publikováno v:
Current eye research. 41(1)
The canonical role of glyceraldehyde phosphate dehydrogenase (GAPDH) is as an enzyme in glycolysis. GAPDH is also a principal "moonlighting" protein with additional roles at diverse sites in a variety of cells. Surface GAPDH on mammalian, yeast, and
Publikováno v:
Alcoholism: Clinical and Experimental Research. 30:1950-1955
Background: Arylsulfatase A (ASA) is an enzyme that catalyzes the degradation of sulfatides, a glycosphingolipid found in many tissues, but predominantly in myelin and kidney. Arylsulfatase A is 1 member of a family of sulfatases that is activated by
Autor:
Peter J. Pierre, Stephen J. Walker, Paul Manowitz, Travis J. Worst, Aaron Xu, Kathleen A. Grant, Kent E. Vrana, Heather L. Green, Laura Beretta, Chinnaswamy Kasinathan, Randy S. Gooch, Paul Thomas
Publikováno v:
Alcoholism: Clinical & Experimental Research. 28:228-232
This article represents the proceedings of a workshop at the 2003 annual meeting of the Research Society on Alcoholism in Fort Lauderdale, FL. The workshop organizers/chairpersons were Chinnaswamy Kasinathan and Paul Manowitz. The presentations were
Publikováno v:
Medical hypotheses. 84(6)
Coordinated growth of eye tissues is required to achieve visual acuity. However, visual experience also guides this process. Experimental myopia can be produced by altering light entering the eye, but also by changing light/dark regimens. Drug discov