Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Chinmoyee Maharana"'
Autor:
Sawan Kumar, Jyotdeep Kour Raina, Amrit Sudershan, Kanak Mahajan, Raman Jasrotia, Chinmoyee Maharana, Rakesh K. Panjalia, Parvinder Kumar
Publikováno v:
European Neurology. 86:55-62
Introduction: Migraine is a neurovascular disorder and is clinically characterized by episodic attacks of mild to severe headaches. Due to the involvement of multiple environmental and genetic factors, it has become a much more complex neurological c
Autor:
Sawan, Kumar, Jyotdeep Kour, Raina, Amrit, Sudershan, Kanak, Mahajan, Raman, Jasrotia, Chinmoyee, Maharana, Rakesh K, Panjalia, Parvinder, Kumar
Publikováno v:
European neurology.
Migraine is a neurovascular disorder and is clinically characterized by episodic attacks of mild to severe headaches. Due to the involvement of multiple environmental and genetic factors, it has become a much more complex neurological condition to un
Publikováno v:
Expert opinion on biological therapy. 22(2)
Biosimilars hold the potential to be an integral healthcare component that can significantly improve affordability and thereby accessibility of the otherwise expensive biotherapeutic products. Regulators, payors, and policymakers, each have a major r
Autor:
Hark Kyun Kim, Jeongmi Lee, Eunae Kim, Seung Hyun Baek, Yoonsuk Cho, Thiruma V. Arumugam, Han-Gyu Bae, Chinmoyee Maharana, Leon F. Palomera, Sunyoung Park, A-Ryeong Gwon, Junsik Kim, Mark P. Mattson, Yongeun Cho, Jihoon Han, Dong-Gyu Jo, Hee Jin Park, Jae Hoon Sul, Jinsu Park
Publikováno v:
Theranostics
Mitochondrial dysfunction and oxidative stress are frequently observed in the early stages of Alzheimer's disease (AD). Studies have shown that presenilin-1 (PS1), the catalytic subunit of γ-secretase whose mutation is linked to familial AD (FAD), l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::088eecb2df7ae0d5febc7c7d54207eb3
Publikováno v:
Journal of pharmaceutical and biomedical analysis. 186
Differential scanning fluorimetry (DSF) or thermal shift has emerged in recent years as a high-throughput screening method in biotherapeutic formulation studies. The present article reports on a fast-track assessment platform for rapid investigation
Autor:
Erez, Eitan, Emmette R, Hutchison, Krisztina, Marosi, James, Comotto, Maja, Mustapic, Saket M, Nigam, Caitlin, Suire, Chinmoyee, Maharana, Gregory A, Jicha, Dong, Liu, Vasiliki, Machairaki, Kenneth W, Witwer, Dimitrios, Kapogiannis, Mark P, Mattson
Publikováno v:
NPJ Aging and Mechanisms of Disease
Alzheimer’s disease (AD) is an age-related neurodegenerative disorder in which aggregation-prone neurotoxic amyloid β-peptide (Aβ) accumulates in the brain. Extracellular vesicles (EVs), including exosomes, are small 50–150 nm membrane vesicles
Autor:
Ruiqian Wan, Aiwu Cheng, Yong Liu, Ye Zhou, Ying Yang, Daoyuan Lu, Mark P. Mattson, Krisztina Marosi, Magdalena Misiak, Vilhelm A. Bohr, Wei Peng, Chinmoyee Maharana
The impact of mitochondrial protein acetylation status on neuronal function and vulnerability to neurological disorders is unknown. Here we show that the mitochondrial protein deacetylase SIRT3 mediates adaptive responses of neurons to bioenergetic,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::baa76b921aa4646d0c65601f92000987
https://europepmc.org/articles/PMC5141613/
https://europepmc.org/articles/PMC5141613/
Publikováno v:
Neuroscience. 167:354-360
Phosphorylation is critically involved in synaptic plasticity and memory. Recent studies have shown that another posttranslational modification, acetylation, particularly of histone H3, also plays important roles in long-term potentiation and memory.
Publikováno v:
Scientific Reports
Phosphorylation plays important roles in several processes including synaptic plasticity and memory. The critical role of extracellular signal-regulated kinase (ERK) in these processes is well established. ERK is activated in a sustained manner by di