Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Chinmoy Pramanik"'
Autor:
Sudhir P. Chaskar, Ramchandra Honparkhe, Jagdish Chavan, Amit Dhumal, Narendra K. Tripathy, Chinmoy Pramanik, Ashok Chaudhari, Rakesh G. Thorat, Mukund K. Gurjar
Publikováno v:
Journal of Heterocyclic Chemistry.
Autor:
Ashok Chaudhari, Chinmoy Pramanik, Pradeep Patil, Hanmant Vedpathak, Mahesh Bandishti, Narendra K. Tripathy, Mukund K. Gurjar
Publikováno v:
Journal of Heterocyclic Chemistry. 59:1054-1063
Autor:
Kiran Bapat, Sudhir P. Chaskar, Sandeep Kotharkar, Narendra K. Tripathy, Chinmoy Pramanik, Dinkar Gotrane, Pradip Patil, Yogesh More, Ulhas Supadu Mahajan
Publikováno v:
Organic Process Research & Development. 23:1252-1256
An efficient, short manufacturing process for fenspiride hydrochloride is reported. Nitro-aldol condensation is the key reaction in the developed process. Improved routes to key building blocks are demonstrated by expedient multikilogram production.
Autor:
Rangarao Kolla, Mukund G. Kulkarni, Narendra Kumar Tripathy, Chinmoy Pramanik, Srinivasarao Sompalli, Kiran Bapat, Ashok Chaudhari, Mukund K. Gurjar
Publikováno v:
Organic Process Research & Development. 18:495-500
Commercial manufacturing of benzphetamine hydrochloride along with its impurity profiling is disclosed. Deoxygenation of pseudoephedrine is reported with ∼100% retention by shielding the amine group as its tert-butyl carbamate, which is very straig
Autor:
Mukund K. Gurjar, Narendra Kumar Tripathy, Sandeep Kotharkar, Yogesh More, Tushar P. Khaladkar, Balaji Vasant Chaugule, Kaliaperumal Neelakandan, Ashok Chaudhari, Ajit S. Borhade, Mukund G. Kulkarni, Chinmoy Pramanik, Pradip Patil, Dinkar Gotrane
Publikováno v:
Organic Process Research & Development. 18:152-156
A commercially viable manufacturing process for propofol (1) is described. The process avoids acid–base neutralization events during isolation of intermediate, 2,6-di-isopropylbenzoic acid (3) and crude propofol, and thus simplifies the synthesis o
Autor:
Gayathri Chandrasekar, Sridhar Balasubramanian, Prabhat Arya, Lakshindra Chetia, Naveen Kumar Mallurwar, Satish Srinivas Kitambi, Chinmoy Pramanik, Madhu Aeluri
Publikováno v:
Organic Letters. 15:436-439
A highly practical and modular synthesis to obtain a diverse 14-membered ring-based macrocyclic toolbox is achieved. These compounds were further tested in zebrafish assays related to early embryonic development, angiogenesis, and neurogenesis, respe
Publikováno v:
Organic Process Research & Development. 16:1591-1597
Darifenacin is a potent and competitive M3 selective receptor antagonist (M3SRA), and its hydrobromide salt (1) is the active ingredient of pharmaceutical formulations for oral treatment of urinary incontinence. The present work demonstrates an effic
Autor:
Sandeep Kotharkar, Chinmoy Pramanik, Sanjay Shankar Deshmukh, Narendra Kumar Tripathy, Mukund K. Gurjar, Raghvendra R. Hivarekar, Ashok Chaudhari
Publikováno v:
Organic Process Research & Development. 16:824-829
During process optimization of Escitalopram oxalate novel impurities, 6 and 7 were observed, which were isolated and characterized, and the proposed structure was confirmed by chemical synthesis. Investigation of the cause of impurities formation imp
Autor:
Narendra Kumar Tripathy, Pravinkumar Khairnar, Mukund K. Gurjar, Rahul Bhumkar, Ganesh Kaluram Karhade, Chinmoy Pramanik
Publikováno v:
Organic Process Research & Development. 16:507-511
During the commercial manufacturing of antimigraine drug Rizatriptan benzoate, several impurities are reported to be formed. This present work demonstrates a convergent and short synthesis of the most critical impurity (C) of Rizatriptan, [2-(5-((1H-
A Short and Efficient Synthetic Strategy for the Total Syntheses of (S)-(+)- and (R)-(–)-Plakolide A
Publikováno v:
European Journal of Organic Chemistry. 2007:5059-5063
Concise and efficient total syntheses of anticancer agents (S)-(+)-Plakolide A and (R)-(–)-Plakolide A were accomplished in eight steps and an overall yield of 39 % starting from geraniol. The key steps in our strategy are Sharpless asymmetric epox