Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Chinmay K. Mukhopadhyay"'
Publikováno v:
ACS Omega. 7:27804-27817
Cisplatin is an important chemotherapeutic drug for the treatment of solid tumors but often causes nephropathy as part of the off-target toxicity. Iron accumulation and related damage were implicated in cisplatin-induced kidney injury. However, the r
Autor:
Sandhya Sen, Saswat Kumar Bal, Sameeksha Yadav, Pragya Mishra, Vishnu Vivek G, Ruchir Rastogi, Chinmay K. Mukhopadhyay
Publikováno v:
The Journal of biological chemistry. 298(12)
Iron (Fe) sequestration is one of the most important strategies of the host to control the growth and survival of invading pathogens. Ferritin (Ft) plays a pivotal role in the sequestration mechanism of mammalian hosts by storing Fe. Recent evidence
Autor:
Ayushi Aggarwal, Hafiz M. Ahmad, Ayeman Amanullah, Zahid Ashraf, Gargi Bagchi, Ajay Bahl, Sudha Bhattacharya, Shankar Chanchal, Ishani Dasgupta, Anindita Dasgupta, Savita Devi, Anindita Dutta, Shyamal K. Goswami, Manish Goyal, Saddam Hussain, Buddhi Prakash Jain, Yashika Jawa, Bibekananda Kar, Yasir Khan, Madhu Khullar, Avinash Kumar, Sangeeta Kumari, Pragya Mishra, Alapani Mitra, Debashis Mitra, Anupam Mittal, Chinmay K. Mukhopadhyay, Rohini Muthuswami, Sandeep Ojha, Shweta Pandey, Rashmi Pathak, Vibha Rani, Ankit Sabharwal, Tapan Sharma, Swati Sharma, Smriti Shreya, Karina Simantov, Ramandeep Singh, Saba Tabasum, Anjali Tripathi, Rakesh K. Tyagi, Monika Yadav, Sameeksha Yadav
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2cf64760fa388de6b8e65db684dbcdb4
https://doi.org/10.1016/b978-0-323-91305-8.01002-4
https://doi.org/10.1016/b978-0-323-91305-8.01002-4
Publikováno v:
Integrated Omics Approaches to Infectious Diseases ISBN: 9789811606908
Metabolomics helps us to understand the metabolism of biological systems and also metabolic interaction between host and parasites. This chapter describes the methodology of metabolite extraction and derivatization from the biological samples with re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1230418536eccfe403bfc8d844e2379d
https://doi.org/10.1007/978-981-16-0691-5_21
https://doi.org/10.1007/978-981-16-0691-5_21
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e62128 (2013)
Oxygen sensing transcription factor HIF-1 is activated due to accumulation of regulatory subunit HIF-1α by posttranslational stability mechanism during hypoxia or by several other stimuli even in normoxia. HIF-1α is also regulated by NF-kB mediated
Externí odkaz:
https://doaj.org/article/f40011308b574df7831926a5b2988d57
Autor:
Amit Kumar Singh, Chaitali Mukhopadhyay, Sudipta Biswas, Vandana Kumari Singh, Chinmay K Mukhopadhyay
Publikováno v:
PLoS ONE, Vol 7, Iss 6, p e38489 (2012)
Recent evidence established a crucial role for mammalian oxygen sensing transcription factor hypoxia inducible factor-1 (HIF-1) in innate immunity against intracellular pathogens. In response to most of these pathogens host phagocytes increase transc
Externí odkaz:
https://doaj.org/article/f32d05a94a87498b9bddf7b05f1e9d70
Publikováno v:
Molecular and Cellular Biochemistry. 454:153-163
Recent literature suggested an important function of native amyloid precursor protein (APP) as amine oxidase implicating in protection of brain cells from catecholamine-induced toxicity. However, any role of catecholamines on regulation of native APP
Autor:
Dola Das, Xiu Luo, Ajay Singh, Yaping Gu, Soumya Ghosh, Chinmay K Mukhopadhyay, Shu G Chen, Man-Sun Sy, Qingzhong Kong, Neena Singh
Publikováno v:
PLoS ONE, Vol 5, Iss 7, p e11420 (2010)
Imbalance of iron homeostasis has been reported in sporadic Creutzfeldt-Jakob-disease (sCJD) affected human and scrapie infected animal brains, but the contribution of this phenotype to disease associated neurotoxicity is unclear.Using cell models of
Externí odkaz:
https://doaj.org/article/d3e06d1f51444ecdba47c1d0ad74def9
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-14 (2017)
Scientific Reports
Scientific Reports
Micronutrients are essential for survival and growth for all the organisms including pathogens. In this manuscript, we report that zinc (Zn) chelator N,N,N’,N’-tetrakis(2-pyridinylmethyl)-1,2-ethylenediamine (TPEN) affects growth and viability of