Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Chinmay G. Patkar"'
Publikováno v:
Antimicrobial Agents and Chemotherapy. 53:4103-4114
Flaviviruses cause severe disease in humans and are a public health priority worldwide. However, no effective therapies or drugs are commercially available yet. Several flavivirus replicon-based assays amenable to high-throughput screening of inhibit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c95facc4d03f7dd15070e54b07efdc4
https://doi.org/10.1128/aac.00074-09
https://doi.org/10.1128/aac.00074-09
Publikováno v:
Journal of Virology. 81:6471-6481
Although it is known that the flavivirus capsid protein is essential for genome packaging and formation of infectious particles, the minimal requirements of the dimeric capsid protein for virus assembly/disassembly have not been characterized. By use
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33f04177da013c037646ec7dbc926ccb
https://doi.org/10.1128/jvi.02120-06
https://doi.org/10.1128/jvi.02120-06
Publikováno v:
Virology. 331(2):247-259
Subgenomic replicons of yellow fever virus (YFV) were constructed to allow expression of heterologous reporter genes in a replication-dependent manner. Expression of the antibiotic resistance gene neomycin phosphotransferase II (Neo) from one of thes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e5fbf85a7210c8873d437876e451619
Cell culture models are used widely to study the effects of dengue virus (DENV) on host cell function. Current methods of identification of cells infected with an unmodified DENV requires fixation and permeablization of cells to allow DENV-specific a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bdab78dbf3484173c38ed7aaa3aed73
https://europepmc.org/articles/PMC4342618/
https://europepmc.org/articles/PMC4342618/
Publikováno v:
The American Journal of Tropical Medicine and Hygiene
Dengue hemorrhagic fever is characterized by a unique vascular leakage syndrome. The mechanisms of endothelial barrier dysfunction in dengue hemorrhagic fever are not well understood. We examined the modulation of endothelial barrier function in deng
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4508cbc76bc9f98b34d94b237111d9b
https://pubmed.ncbi.nlm.nih.gov/23149581
https://pubmed.ncbi.nlm.nih.gov/23149581
In this case report, Staphylococcus aureus was found to persist in an 85-year-old woman 75 years after the successful treatment of osteomyelitis during her childhood.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb14d81b2ab9114ba3c58aa6b8cfae8c
https://europepmc.org/articles/PMC3872831/
https://europepmc.org/articles/PMC3872831/
Autor:
Long Li, Zhigang Zhou, Carol Beth Post, Mansoora Khaliq, Jae-Eun Suk, Richard J. Kuhn, Chinmay G. Patkar
Publikováno v:
ACS chemical biology. 3(12)
Infection by the mosquito-borne dengue virus causes dengue fever and the sometimes fatal dengue hemorrhagic fever. The increasing number of dengue infections per year suggests that the virus is becoming more virulent and its transmission is expanding
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb5d4e6e6f30a43e4d6ada27e8126074
https://pubmed.ncbi.nlm.nih.gov/19053243
https://pubmed.ncbi.nlm.nih.gov/19053243
Autor:
Richard J. Kuhn, Chinmay G. Patkar
Publikováno v:
New Treatment Strategies for Dengue and Other Flaviviral Diseases: Novartis Foundation Symposium 277
Dengue virus is responsible for a significant amount of human disease in predominantly tropical areas of the world. Much effort has focused on the development of vaccines against the four serotypes of dengue, and within the next few years a vaccine i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3aad2dee2a0ffd74d88c3ac26ece9dde
https://doi.org/10.1002/0470058005.ch4
https://doi.org/10.1002/0470058005.ch4
Publikováno v:
Journal of leukocyte biology. 84(4)
Dengue virus (DENV), a re-emerging arbovirus, readily infects dendritic cells (DC) in culture and in vivo. However, there have been contradictory reports regarding the effect of DENV infection on DC activation and maturation. DC undergo a series of f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f283a6c05445992053ea9fe2752a9a0
https://pubmed.ncbi.nlm.nih.gov/18653464
https://pubmed.ncbi.nlm.nih.gov/18653464
Autor:
Richard J. Kuhn, Chinmay G. Patkar
Publikováno v:
Journal of virology. 82(7)
In flaviviruses it has been proposed that there is a coupling between genome replication and virion assembly and that nonstructural proteins are involved in this process. It was previously reported that mutations in yellow fever virus (YFV) nonstruct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e4359633930402958fc1b11831fe0db
https://pubmed.ncbi.nlm.nih.gov/18199634
https://pubmed.ncbi.nlm.nih.gov/18199634