Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Chinh T, Bui"'
Autor:
Xuan T. T. Phan, Binh Van Ngo, Huy D. Nguyen, Quang T. Hoang, Chung D. Ngo, Chinh T. Bui, Ty Nguyen, Nghiep T. Hoang
Publikováno v:
Russian Journal of Herpetology. 29:284-297
Studies on genetic relationships and phylogenetic origins, and mutations in nucleotide of Leiolepis in central Vietnam are limited. In this study, thirty-five representative samples of four species (Leiolepis reevesii, L. guttata, L. guentherpetersi,
Autor:
Mark F. van Delft, Meng Xiao Luo, Kate McArthur, Peter E. Czabotar, Jarrod J. Sandow, Laura F. Dagley, Kym N Lowes, Jason M. Brouwer, Andrew I. Webb, Guillaume Lessene, Rachael M. Lane, Keith G. Watson, Christoph Grohmann, Ahmad Wardak, Peter M. Colman, Sabrina Bernard, Soo San Wan, Yelena Khakham, Phillip P. Sharp, Romina Lessene, Thao Nguyen, David J. Segal, David C.S. Huang, Erinna F. Lee, Lucy Li, Marlyse A. Debrincat, Grant Dewson, Chinh T. Bui, Hui San Chin, W. Douglas Fairlie, Stephane Duflocq, Benjamin T. Kile, Stephane Chappaz, Caroline Miles, Kurt Lackovic, Laure Peilleron
Publikováno v:
Nature Chemical Biology. 15:1057-1066
Activating the intrinsic apoptosis pathway with small molecules is now a clinically validated approach to cancer therapy. In contrast, blocking apoptosis to prevent the death of healthy cells in disease settings has not been achieved. Caspases have b
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Autor:
Chinh T. Bui
Publikováno v:
Synthetic Communications. 44:1122-1127
An improved one-pot synthesis of 3,4-disubstituted 2-quinolinones is described. The condensation of substituted 2-aminobenzophenone (or 2-aminophenyl alkyl ketone) with acid chlorides was carried out in the presence of triethylamine (or NaH) under mi
Autor:
Mark F, van Delft, Stephane, Chappaz, Yelena, Khakham, Chinh T, Bui, Marlyse A, Debrincat, Kym N, Lowes, Jason M, Brouwer, Christoph, Grohmann, Phillip P, Sharp, Laura F, Dagley, Lucy, Li, Kate, McArthur, Meng-Xiao, Luo, Hui San, Chin, W Douglas, Fairlie, Erinna F, Lee, David, Segal, Stephane, Duflocq, Romina, Lessene, Sabrina, Bernard, Laure, Peilleron, Thao, Nguyen, Caroline, Miles, Soo San, Wan, Rachael M, Lane, Ahmad, Wardak, Kurt, Lackovic, Peter M, Colman, Jarrod J, Sandow, Andrew I, Webb, Peter E, Czabotar, Grant, Dewson, Keith G, Watson, David C S, Huang, Guillaume, Lessene, Benjamin T, Kile
Publikováno v:
Nature chemical biology. 15(11)
Activating the intrinsic apoptosis pathway with small molecules is now a clinically validated approach to cancer therapy. In contrast, blocking apoptosis to prevent the death of healthy cells in disease settings has not been achieved. Caspases have b
Publikováno v:
Current Pharmacogenomics. 2:325-332
Publikováno v:
Biopolymers. 70:628-636
The electrophoretic gel-based chemical cleavage of the mismatch method gives an incomplete view of the DNA conformational changes induced by a single base mismatch. This spectroscopic study investigates the permanganate oxidation reactions with match
Publikováno v:
Nucleosides, Nucleotides and Nucleic Acids. 22:1835-1855
KMnO4 has been well known as a powerful chemical probe for numerous applications in biological fields, particularly for those used in conformational studies of DNA. The KMnO4 assay provides essential information for understanding biochemical processe
Publikováno v:
Bioorganic Chemistry. 30:216-232
The last decade has witnessed many exciting scientific publications associated with site-selective reactions of small chemical molecules with imperfectly matched DNA. Typical examples are carbodiimide, hydroxylamine, potassium permanganate, osmium te
Autor:
Brad E. Sleebs, Philippe Bergeron, Jonathan B. Baell, Wilhelmus J A Kersten, Zhi-Fu Tao, Lisa A. Hasvold, Paul Gibbons, Keith G. Watson, Michael F. T. Koehler, Wayne J. Fairbrother, Carl S. Rye, Sanjitha Kulasegaram, Guillaume Lessene, Chinh T. Bui, Brian J. Smith, Peter M. Colman, Le Wang, Edna F. Choo, Danette Dudley, Steven W. Elmore, David C.S. Huang, Chudi Ndubaku, Kevin Lau, Peter E. Czabotar, John A. Flygare, Andrew J. Souers, George Nikolakopoulos
Publikováno v:
ACS medicinal chemistry letters. 5(6)
Because of the promise of BCL-2 antagonists in combating chronic lymphocytic leukemia (CLL) and non-Hodgkin’s lymphoma (NHL), interest in additional selective antagonists of antiapoptotic proteins has grown. Beginning with a series of selective, po