Zobrazeno 1 - 10
of 81
pro vyhledávání: '"Chinglai Yang"'
Autor:
Ying Liu, Ling Ye, Fang Lin, Yasmine Gomaa, David Flyer, Ricardo Carrion, Jean L. Patterson, Mark R. Prausnitz, Gale Smith, Gregory Glenn, Hua Wu, Richard W. Compans, Chinglai Yang
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/ff2b5d4e8873422293eb5e1c62295876
Autor:
Ying Liu, Zhiyuan Wen, Ricardo Carrion, Jerritt Nunneley, Hilary Staples, Anysha Ticer, Jean L. Patterson, Richard W. Compans, Ling Ye, Chinglai Yang
Publikováno v:
Frontiers in Microbiology, Vol 11 (2020)
Ebolavirus (EBOV) infection in humans causes severe hemorrhagic fevers with high mortality rates that range from 30 to 80% as shown in different outbreaks. Thus the development of safe and efficacious EBOV vaccines remains an important goal for biome
Externí odkaz:
https://doaj.org/article/baecee747b1d491da5b2ca3bff93b862
Autor:
Zhiwu Sun, Yun Zhu, Qian Wang, Ling Ye, Yanyan Dai, Shan Su, Fei Yu, Tianlei Ying, Chinglai Yang, Shibo Jiang, Lu Lu
Publikováno v:
Emerging Microbes and Infections, Vol 5, Iss 1, Pp 1-12 (2016)
After three decades of intensive research efforts, an effective vaccine against HIV-1 remains to be developed. Several broadly neutralizing antibodies to HIV-1, such as 10E8, recognize the membrane proximal external region (MPER) of the HIV-1 gp41 pr
Externí odkaz:
https://doaj.org/article/e3f3bdde87814ac18094b728e5c7b602
Autor:
Yao-Tsun Li, Hui-Ying Ko, Chang-Chun David Lee, Ching-Yu Lai, Chuan-Liang Kao, Chinglai Yang, Won-Bo Wang, Chwan-Chuen King
Publikováno v:
PLoS ONE, Vol 10, Iss 8, p e0133910 (2015)
BackgroundHuman infections with avian influenza viruses (AIVs) have frequently raised global concerns of emerging, interspecies-transmissible viruses with pandemic potential. Waterfowl, the predominant reservoir of influenza viruses in nature, harbor
Externí odkaz:
https://doaj.org/article/bc7451f2df664bcc80fc4fbeb711e37b
Autor:
Chuan-Liang Kao, Ta-Chien Chan, Chu-Han Tsai, Kuan-Ying Chu, Shu-Fang Chuang, Chang-Chun Lee, Zheng-Rong Tiger Li, Ko-Wen Wu, Luan-Yin Chang, Yea-Huei Shen, Li-Min Huang, Ping-Ing Lee, Chinglai Yang, Richard Compans, Barry T Rouse, Chwan-Chuen King
Publikováno v:
PLoS ONE, Vol 7, Iss 2, p e31162 (2012)
The 2009 influenza pandemic provided an opportunity to observe dynamic changes of the hemagglutinin (HA) and neuraminidase (NA) of pH1N1 strains that spread in two metropolitan areas--Taipei and Kaohsiung. We observed cumulative increases of amino ac
Externí odkaz:
https://doaj.org/article/7a394ad3300a4acdba3f2d06f99b734f
Autor:
Yulong Gao, Zhiyuan Wen, Ke Dong, Gongxun Zhong, Xiaomei Wang, Zhigao Bu, Hualan Chen, Ling Ye, Chinglai Yang
Publikováno v:
PLoS ONE, Vol 7, Iss 7, p e41332 (2012)
The evolution of the H5N1 highly pathogenic avian influenza virus (HPAIV) has resulted in high sequence variations and diverse antigenic properties in circulating viral isolates. We investigated immune responses induced by HA DNA vaccines of two cont
Externí odkaz:
https://doaj.org/article/f6991b8183ac48d59a042d51095b490e
Publikováno v:
PLoS Pathogens, Vol 8, Iss 12, p e1003065 (2012)
In addition to its surface glycoprotein (GP(1,2)), Ebola virus (EBOV) directs the production of large quantities of a truncated glycoprotein isoform (sGP) that is secreted into the extracellular space. The generation of secreted antigens has been stu
Externí odkaz:
https://doaj.org/article/ada79b23618e443d9ced2726dd15f7fe
Autor:
Ling Ye, Zhiyuan Wen, Ke Dong, Xi Wang, Zhigao Bu, Huizhong Zhang, Richard W Compans, Chinglai Yang
Publikováno v:
PLoS ONE, Vol 6, Iss 5, p e14813 (2011)
Several conserved neutralizing epitopes have been identified in the HIV Env protein and among these, the MPER of gp41 has received great attention and is widely recognized as a promising target. However, little success has been achieved in eliciting
Externí odkaz:
https://doaj.org/article/b58096c2a82240288714623fcaaa26d1
Autor:
Dongni Kong, Zhiyuan Wen, Hua Su, Jinying Ge, Weiye Chen, Xijun Wang, Chao Wu, Chinglai Yang, Hualan Chen, Zhigao Bu
Publikováno v:
Virology. 573:176-177
Autor:
Mark R. Prausnitz, Dengning Xia, Gaurav Byagathvalli, Chao-Yi Lu, M. Saad Bhamla, Huan Yu, Rui Jin, Chinglai Yang, Ling Ye
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance Low-cost and rapidly distributable vaccines are urgently needed to combat COVID-19 and future pandemics, especially for developing countries and other low-resource settings. DNA vaccines are inexpensive, rapidly developed, and safe, but