Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Chingakham Ranjit, Singh"'
Autor:
Eiji Obayashi, Rafael E. Luna, Takashi Nagata, Pilar Martin-Marcos, Hiroyuki Hiraishi, Chingakham Ranjit Singh, Jan Peter Erzberger, Fan Zhang, Haribabu Arthanari, Jacob Morris, Riccardo Pellarin, Chelsea Moore, Ian Harmon, Evangelos Papadopoulos, Hisashi Yoshida, Mahmoud L. Nasr, Satoru Unzai, Bryttney Thompson, Eric Aube, Samantha Hustak, Florian Stengel, Eddie Dagraca, Asokan Ananbandam, Philip Gao, Takeshi Urano, Alan G. Hinnebusch, Gerhard Wagner, Katsura Asano
Publikováno v:
Cell Reports, Vol 43, Iss 6, Pp 114404- (2024)
Externí odkaz:
https://doaj.org/article/0abf4580bb9d47ceb45f9407f4e57f48
Publikováno v:
STAR Protocols, Vol 3, Iss 4, Pp 101739- (2022)
Summary: eIF5-mimic protein (5MP) controls translation through binding to the ribosomal pre-initiation complex (PIC) and alters non-AUG translation rates for cancer oncogenes and repeat-expansions in neurodegenerative diseases. Here, we describe a se
Externí odkaz:
https://doaj.org/article/02676ba38bcb4cbe8ed6184e6cd9bd2a
Publikováno v:
STAR Protocols, Vol 3, Iss 3, Pp 101615- (2022)
Summary: eIF5-mimic protein (5MP) controls translation through its interaction with eukaryotic translation initiation factor (eIF) 2 and eIF3 and alters non-AUG translation rates for oncogenes in cancer and repeat expansions in neurodegenerative dise
Externí odkaz:
https://doaj.org/article/758261de9fe24f2490d42b41fc075812
Autor:
Chingakham Ranjit Singh, M. Rebecca Glineburg, Chelsea Moore, Naoki Tani, Rahul Jaiswal, Ye Zou, Eric Aube, Sarah Gillaspie, Mackenzie Thornton, Ariana Cecil, Madelyn Hilgers, Azuma Takasu, Izumi Asano, Masayo Asano, Carlos R. Escalante, Akira Nakamura, Peter K. Todd, Katsura Asano
Publikováno v:
Cell Reports, Vol 36, Iss 2, Pp 109376- (2021)
Summary: eIF5-mimic protein (5MP) is a translational regulatory protein that binds the small ribosomal subunit and modulates its activity. 5MP is proposed to reprogram non-AUG translation rates for oncogenes in cancer, but its role in controlling non
Externí odkaz:
https://doaj.org/article/5cad839a14af4e99972d37594a69c639
Autor:
Eiji Obayashi, Rafael E. Luna, Takashi Nagata, Pilar Martin-Marcos, Hiroyuki Hiraishi, Chingakham Ranjit Singh, Jan Peter Erzberger, Fan Zhang, Haribabu Arthanari, Jacob Morris, Riccardo Pellarin, Chelsea Moore, Ian Harmon, Evangelos Papadopoulos, Hisashi Yoshida, Mahmoud L. Nasr, Satoru Unzai, Brytteny Thompson, Eric Aube, Samantha Hustak, Florian Stengel, Eddie Dagraca, Asokan Ananbandam, Philip Gao, Takeshi Urano, Alan G. Hinnebusch, Gerhard Wagner, Katsura Asano
Publikováno v:
Cell Reports, Vol 18, Iss 11, Pp 2651-2663 (2017)
During eukaryotic translation initiation, eIF3 binds the solvent-accessible side of the 40S ribosome and recruits the gate-keeper protein eIF1 and eIF5 to the decoding center. This is largely mediated by the N-terminal domain (NTD) of eIF3c, which ca
Externí odkaz:
https://doaj.org/article/cb9ad045c97d4978ad675e2642cc8c65
Autor:
Hiroaki Kato, Haana Yamada, Madelyn Hilgers, Katsura Asano, Takeshi Urano, Izumi Asano, Chie Mori, Chingakham Ranjit Singh, Ariana Cecil, Mackenzie M. Thornton, Cheyenne Brunkow, Carter Moravek, Yuji Chikashige, Whitney Pepper
Publikováno v:
Nucleic Acids Research
The protein kinase Gcn2 is a central transducer of nutritional stress signaling important for stress adaptation by normal cells and the survival of cancer cells. In response to nutrient deprivation, Gcn2 phosphorylates eIF2α, thereby repressing gene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14e50aa16824b89ccff98da279426901
http://ir.lib.shimane-u.ac.jp/54134
http://ir.lib.shimane-u.ac.jp/54134
Autor:
Yoshihiko Fujita, Takeru Kameda, Chingakham Ranjit Singh, Whitney Pepper, Ariana Cecil, Madelyn Hilgers, Mackenzie Thornton, Izumi Asano, Carter Moravek, Yuichi Togashi, Hirohide Saito, Katsura Asano
Publikováno v:
Science Advances. 8
In contrast to prokaryotes wherein GUG and UUG are permissive start codons, initiation frequencies from non-AUG codons are generally low in eukaryotes, with CUG being considered as strongest. Here, we report that combined 5-cytosine methylation (5mC)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::932407fb623d51c4a5955d40c22bd862
https://doi.org/10.1126/sciadv.abm8501
https://doi.org/10.1126/sciadv.abm8501
Autor:
Chelsea Moore, Madelyn Hilgers, Ariana Cecil, Naoki Tani, Akira Nakamura, Katsura Asano, Ye Zou, Rahul Jaiswal, Peter K. Todd, Chingakham Ranjit Singh, Masayo Asano, Sarah Gillaspie, Eric Aube, Izumi Asano, Mackenzie M. Thornton, Azuma Takasu, M. Rebecca Glineburg, Carlos R. Escalante
Publikováno v:
Cell Reports, Vol 36, Iss 2, Pp 109376-(2021)
Cell Rep
Cell Rep
Summary: eIF5-mimic protein (5MP) is a translational regulatory protein that binds the small ribosomal subunit and modulates its activity. 5MP is proposed to reprogram non-AUG translation rates for oncogenes in cancer, but its role in controlling non
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::650144f6f97c402de64bec1f59bb7541
http://www.sciencedirect.com/science/article/pii/S2211124721007749
http://www.sciencedirect.com/science/article/pii/S2211124721007749
Autor:
Asokan Ananbandam, Hisashi Yoshida, Florian Stengel, Mahmoud L. Nasr, Brytteny Thompson, Takeshi Urano, Fan Zhang, Philip Gao, Haribabu Arthanari, Takashi Nagata, Riccardo Pellarin, Gerhard Wagner, Alan G. Hinnebusch, Jacob Morris, Rafael E. Luna, Katsura Asano, Evangelos Papadopoulos, Chelsea Moore, Eric Aube, Pilar Martin-Marcos, Hiroyuki Hiraishi, Eiji Obayashi, Eddie Dagraca, Jan P. Erzberger, Chingakham Ranjit Singh, Satoru Unzai, Ian Harmon, Samantha Hustak
Publikováno v:
Cell Reports
Cell Reports, 2017, 18 (11), pp.2651-2663. ⟨10.1016/j.celrep.2017.02.052⟩
Cell Reports, Elsevier Inc, 2017, 18 (11), pp.2651-2663. ⟨10.1016/j.celrep.2017.02.052⟩
Cell Reports, 18 (11)
Cell Reports, Vol 18, Iss 11, Pp 2651-2663 (2017)
Cell Reports, 2017, 18 (11), pp.2651-2663. ⟨10.1016/j.celrep.2017.02.052⟩
Cell Reports, Elsevier Inc, 2017, 18 (11), pp.2651-2663. ⟨10.1016/j.celrep.2017.02.052⟩
Cell Reports, 18 (11)
Cell Reports, Vol 18, Iss 11, Pp 2651-2663 (2017)
During eukaryotic translation initiation, eIF3 binds the solvent-accessible side of the 40S ribosome and recruits the gate-keeper protein eIF1 and eIF5 to the decoding center. This is largely mediated by the N-terminal domain (NTD) of eIF3c, which ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e94474aec1da25a265c0c4cdc5072f39
https://doi.org/10.1016/j.celrep.2017.02.052
https://doi.org/10.1016/j.celrep.2017.02.052
Autor:
Abbey Anderson, Masayo Asano, Sarah Gillaspie, Ken-ichi Yoshino, Megan Reid, Brytteny Thompson, Gerhard Wagner, Stefan Rothenburg, Chingakham Ranjit Singh, Hisao Masai, Rafael E. Luna, Jerome C. Nietfeld, Alexander Beeser, Hideaki Tagami, Samantha Hustak, Sherry D. Fleming, Hiroyuki Hiraishi, Christian Cox, Akio Nakashima, J.-P. Perchellet, Emily Archer Slone, Caitlin Kozel, Ushio Kikkawa, Katsura Asano, Evangelos Papadopoulos, Chelsea Moore
Publikováno v:
Nucleic Acids Research
Nucleic acids research, vol 44, iss 18
Nucleic acids research, vol 44, iss 18
ATF4 is a pro-oncogenic transcription factor whose translation is activated by eIF2 phosphorylation through delayed re-initiation involving two uORFs in the mRNA leader. However, in yeast, the effect of eIF2 phosphorylation can be mimicked by eIF5 ov
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b967ed7ab95a71076403b3e6554978c6
http://europepmc.org/articles/PMC5062967
http://europepmc.org/articles/PMC5062967