Zobrazeno 1 - 1
of 1
pro vyhledávání: '"Ching-Shyi Peter Wu"'
Autor:
Bing-Ze Yang, Mei-Yin Liu, Kuan-Lin Chiu, Yuh-Ling Chien, Ching-An Cheng, Yu-Lin Chen, Li-Yu Tsui, Keng-Ru Lin, Hsueh-Ping Catherine Chu, Ching-Shyi Peter Wu
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract RNA helicase DHX9 is essential for genome stability by resolving aberrant R-loops. However, its regulatory mechanisms remain unclear. Here we show that SUMOylation at lysine 120 (K120) is crucial for DHX9 function. Preventing SUMOylation at
Externí odkaz:
https://doaj.org/article/d20bd17269914d3baa35b3b2dd79b01d
