Zobrazeno 1 - 10
of 112
pro vyhledávání: '"Ching-Ling Lien"'
Autor:
Narasimman Gurusamy, Olaf Bergmann, Clotilde Castaldo, Ngan F. Huang, Ching-Ling Lien, Jun Jie Tan, Felix B. Engel
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 11 (2024)
Externí odkaz:
https://doaj.org/article/a338a094b1de43c3bb1601aa8115c713
Publikováno v:
STAR Protocols, Vol 5, Iss 2, Pp 102973- (2024)
Summary: The characterization of cell populations that reside in the outer layer of the heart has been hindered by difficulties in their isolation. Here, we present a protocol for isolation and single-nuclei multiomic analyses of the human fetal epic
Externí odkaz:
https://doaj.org/article/8cfc6e7ebfdb4d4fb107050167f33621
Autor:
Stanislao Igor Travisano, Michael R.M. Harrison, Matthew E. Thornton, Brendan H. Grubbs, Thomas Quertermous, Ching-Ling Lien
Publikováno v:
Cell Reports, Vol 42, Iss 9, Pp 113106- (2023)
Summary: Cardiac lymphatic vessels play important roles in fluid homeostasis, inflammation, disease, and regeneration of the heart. The developing cardiac lymphatics in human fetal hearts are closely associated with coronary arteries, similar to thos
Externí odkaz:
https://doaj.org/article/66eada1a9c3d400fb3208df2169fb9cc
Autor:
Viviana M. Fajardo, Iris Feng, Bao Ying Chen, Cesar A. Perez-Ramirez, Baochen Shi, Peter Clark, Rong Tian, Ching-Ling Lien, Matteo Pellegrini, Heather Christofk, Haruko Nakano, Atsushi Nakano
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract The mammalian heart switches its main metabolic substrate from glucose to fatty acids shortly after birth. This metabolic switch coincides with the loss of regenerative capacity in the heart. However, it is unknown whether glucose metabolism
Externí odkaz:
https://doaj.org/article/35f4d047b40e4f74bc40708dc8bfcb3a
Autor:
Hua Shen, Peiheng Gan, Kristy Wang, Ali Darehzereshki, Kai Wang, S Ram Kumar, Ching-Ling Lien, Michaela Patterson, Ge Tao, Henry M Sucov
Publikováno v:
eLife, Vol 9 (2020)
Injury to the newborn mouse heart is efficiently regenerated, but this capacity is lost by one week after birth. We found that IGF2, an important mitogen in heart development, is required for neonatal heart regeneration. IGF2 originates from the endo
Externí odkaz:
https://doaj.org/article/8be7bfa9281e41649897b02d257b1eff
Autor:
Michael RM Harrison, Xidi Feng, Guqin Mo, Antonio Aguayo, Jessi Villafuerte, Tyler Yoshida, Caroline A Pearson, Stefan Schulte-Merker, Ching-Ling Lien
Publikováno v:
eLife, Vol 8 (2019)
The cardiac lymphatic vascular system and its potentially critical functions in heart patients have been largely underappreciated, in part due to a lack of experimentally accessible systems. We here demonstrate that cardiac lymphatic vessels develop
Externí odkaz:
https://doaj.org/article/57b8bfbbe6fe462c9b426e0207f7dc7a
Publikováno v:
Journal of Cardiovascular Development and Disease, Vol 8, Iss 2, p 21 (2021)
Heart disease remains the single largest cause of death in developed countries, and novel therapeutic interventions are desperately needed to alleviate this growing burden. The cardiac lymphatic system is the long-overlooked counterpart of the corona
Externí odkaz:
https://doaj.org/article/cd5c0213a2b14ea3b63a91f1771a6721
Publikováno v:
Sensors, Vol 19, Iss 19, p 4094 (2019)
This paper reports the feasibility of Nakagami imaging in monitoring the regeneration process of zebrafish hearts in a noninvasive manner. In addition, spectral Doppler waveforms that are typically used to access the diastolic function were measured
Externí odkaz:
https://doaj.org/article/37a4774a483e4b61aeefd77dd741de59
Publikováno v:
Journal of Cardiovascular Development and Disease, Vol 5, Iss 4, p 59 (2018)
Functional coronary circulation is essential for a healthy heart in warm-blooded vertebrates, and coronary diseases can have a fatal consequence. Despite the growing interest, the knowledge about the coronary vessel development and the roles of new c
Externí odkaz:
https://doaj.org/article/017a67a93a514e3a9391f56ebf9511bf
Publikováno v:
The Scientific World Journal, Vol 6, Pp 38-54 (2006)
Regeneration of severed limbs in adult animals is restricted to urodele amphibians. Mammals, including humans, have very limited regenerative capabilities and even with proper treatment, only the tips of our digits can grow back. Teleost fish can reg
Externí odkaz:
https://doaj.org/article/1490ad2c25f3496faa1a07bbd3019a5f