Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Ching-Chieh Tung"'
Autor:
Razvan L. Cornea, Ching-Chieh Tung, Daniel P. Singh, Filip Van Petegem, Donald M. Bers, Bengt Svensson, Kaja Rožman, Levy M. Treinen, Siobhan M. Wong King Yuen, Courtney C. Aldrich, Bradley S. Launikonis, Jingyan Zhang, David D. Thomas, Aleksey V. Zima, Jacob A. Schwarz, Christopher Y. Ko, Roman Nikolaienko
Publikováno v:
The Journal of biological chemistry, vol 298, iss 1
The Journal of Biological Chemistry
The Journal of Biological Chemistry
The N-terminal region (NTR) of ryanodine receptor (RyR) channels is critical for the regulation of Ca2+ release during excitation–contraction (EC) coupling in muscle. The NTR hosts numerous mutations linked to skeletal (RyR1) and cardiac (RyR2) myo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62e651b16da8560235f301c406f3eb42
https://escholarship.org/uc/item/1sw1d750
https://escholarship.org/uc/item/1sw1d750
Publikováno v:
Proceedings of the National Academy of Sciences. 116:10763-10772
Voltage-gated sodium (Na V ) and calcium channels (Ca V ) form targets for calmodulin (CaM), which affects channel inactivation properties. A major interaction site for CaM resides in the C-terminal (CT) region, consisting of an IQ domain downstream
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0fede0720d8471ff42b59c73f9a48bc3
https://doi.org/10.1073/pnas.1818618116
https://doi.org/10.1073/pnas.1818618116
Autor:
Bengt Svensson, Ro man K, Courtney C. Aldrich, David D. Thomas, Schwarz Ja, Yuen Smwk, Van Petegem F, Jiaxue Zhang, Ching-Chieh Tung, Treinen Lm, Razvan L. Cornea, Robyn T. Rebbeck
The N-terminal region (NTR) of the ryanodine receptor (RyR) calcium channels is critical to the regulation of Ca2+release during excitation-contraction coupling. NTR hosts numerous mutations linked to skeletal and cardiac myopathies (RyR1 and RyR2, r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6319e243127ef90afa670e74191e682f
https://doi.org/10.1101/2021.02.07.430153
https://doi.org/10.1101/2021.02.07.430153
Publikováno v:
Biophysical Journal. 118:576a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::16ccab6f64ba5822e17c68cb48290cf5
https://doi.org/10.1016/j.bpj.2019.11.3128
https://doi.org/10.1016/j.bpj.2019.11.3128
Autor:
Ricardo E. Rivera-Acevedo, Bernd R. Gardill, Filip Van Petegem, Mark Okon, Ching-Chieh Tung, Lawrence P. McIntosh
Publikováno v:
Scientific Reports
Scientific Reports, Vol 8, Iss 1, Pp 1-13 (2018)
Scientific Reports, Vol 8, Iss 1, Pp 1-13 (2018)
Voltage-gated sodium channels (NaV) are responsible for the rapid depolarization of many excitable cells. They readily inactivate, a process where currents diminish after milliseconds of channel opening. They are also targets for a multitude of disea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5cd2b33a70ef7d8771681ba06b9223ed
http://europepmc.org/articles/PMC5852250
http://europepmc.org/articles/PMC5852250
Autor:
Ching-Chieh Tung, Filip Van Petegem, Marta Campiglio, Siobhan M. Wong King Yuen, Bernhard E. Flucher
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance Skeletal muscle contraction is a tightly orchestrated event that starts with the depolarization of the T-tubular membrane. At the center is a functional and mechanical coupling between two membrane proteins: L-type voltage-gated calcium
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c662f4245f96bd6f68c60fd91b3d1c3e
https://pubmed.ncbi.nlm.nih.gov/29078335
https://pubmed.ncbi.nlm.nih.gov/29078335
Publikováno v:
Nature. 11/25/2010, Vol. 468 Issue 7323, p585-588. 4p. 4 Diagrams.
Autor:
Anna-Carin C. Carlsson, Lynn Kimlicka, Zhiguang Yuchi, Filip Van Petegem, Ching-Chieh Tung, Paolo A. Lobo
Publikováno v:
Structure. 21(8):1440-1449
SummaryRyanodine receptors (RyRs) are calcium release channels located in the membrane of the endoplasmic and sarcoplasmic reticulum and play a major role in muscle excitation-contraction coupling. The cardiac isoform (RyR2) is the target for >150 mu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::202d853310876c6c2768fd1da9b5d7f1
Publikováno v:
The Plant journal : for cell and molecular biology. 89(4)
The xyloglucan endo-transglycosylase/hydrolase (XTH) gene family encodes enzymes of central importance to plant cell wall remodelling. The evolutionary history of plant XTH gene products is incompletely understood vis-à-vis the larger body of bacter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3aaeb9e7c1efe9bf306eb565092638be
https://pubmed.ncbi.nlm.nih.gov/27859885
https://pubmed.ncbi.nlm.nih.gov/27859885
Publikováno v:
Proceedings of the National Academy of Sciences. 109:3558-3563
Voltage-gated sodium channels underlie the rapid regenerative upstroke of action potentials and are modulated by cytoplasmic calcium ions through a poorly understood mechanism. We describe the 1.35 Å crystal structure of Ca 2+ -bound calmodulin (Ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::291af12a7754c20a473ba6d7636aa4e8
https://doi.org/10.1073/pnas.1114748109
https://doi.org/10.1073/pnas.1114748109