Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Ching-Chieh Chou"'
Autor:
Bilal Khalil, Deepak Chhangani, Melissa C. Wren, Courtney L. Smith, Jannifer H. Lee, Xingli Li, Christian Puttinger, Chih-Wei Tsai, Gael Fortin, Dmytro Morderer, Junli Gao, Feilin Liu, Chun Kim Lim, Jingjiao Chen, Ching-Chieh Chou, Cara L. Croft, Amanda M. Gleixner, Christopher J. Donnelly, Todd E. Golde, Leonard Petrucelli, Björn Oskarsson, Dennis W. Dickson, Ke Zhang, James Shorter, Shige H. Yoshimura, Sami J. Barmada, Diego E. Rincon-Limas, Wilfried Rossoll
Publikováno v:
Molecular Neurodegeneration, Vol 17, Iss 1, Pp 1-27 (2022)
Abstract Background Cytoplasmic mislocalization and aggregation of TAR DNA-binding protein-43 (TDP-43) is a hallmark of the amyotrophic lateral sclerosis and frontotemporal dementia (ALS/FTD) disease spectrum, causing both nuclear loss-of-function an
Externí odkaz:
https://doaj.org/article/bbd064334e3c44abbee70cb5d84f3100
Autor:
Alyssa N. Coyne, Ileana Lorenzini, Ching-Chieh Chou, Meaghan Torvund, Robert S. Rogers, Alexander Starr, Benjamin L. Zaepfel, Jennifer Levy, Jeffrey Johannesmeyer, Jacob C. Schwartz, Hiroshi Nishimune, Konrad Zinsmaier, Wilfried Rossoll, Rita Sattler, Daniela C. Zarnescu
Publikováno v:
Cell Reports, Vol 21, Iss 1, Pp 110-125 (2017)
Amyotrophic lateral sclerosis (ALS) is a synaptopathy accompanied by the presence of cytoplasmic aggregates containing TDP-43, an RNA-binding protein linked to ∼97% of ALS cases. Using a Drosophila model of ALS, we show that TDP-43 overexpression (
Externí odkaz:
https://doaj.org/article/864d5b20cac14a2c8ea1e98ca71ebe07
Autor:
Paul G. Donlin-Asp, Claudia Fallini, Jazmin Campos, Ching-Chieh Chou, Megan E. Merritt, Han C. Phan, Gary J. Bassell, Wilfried Rossoll
Publikováno v:
Cell Reports, Vol 18, Iss 7, Pp 1660-1673 (2017)
Spinal muscular atrophy (SMA) is a motor neuron disease caused by reduced levels of the survival of motor neuron (SMN) protein. SMN is part of a multiprotein complex that facilitates the assembly of spliceosomal small nuclear ribonucleoproteins (snRN
Externí odkaz:
https://doaj.org/article/0a8ea1b0aa38402bab1ce8c4168249f7
Autor:
Shun-Hwa Wei, Yu-Fen Chuang, Chia-Ying Fang, Ming-Yuh Yeh, Miao-Ju Hsu, Hsiao-Lung Chan, Ching-Chieh Chou, Ya-Ju Chang, Hen-Yu Lien
Publikováno v:
Sensors, Vol 12, Iss 12, Pp 16353-16367 (2012)
The aim of this study was to examine the change of the intermuscular cross-correlation and coherence of the rectus femoris (RF), vastus medialis (VM) and vastus lateralis (VL) during exhausting stepping exercise. Eleven healthy adults repeated the st
Externí odkaz:
https://doaj.org/article/ab926292dfd84b9aa1c5215d92cdc6f1
Autor:
Ching-Chieh Chou, 周靖傑
97
Knee osteoarthritis (OA) is a common disorder of synovial joints and the prevalence increases with aging. The primary symptom is refractory joint pain accompanying with secondary muscle weakness and functional disability due to different mech
Knee osteoarthritis (OA) is a common disorder of synovial joints and the prevalence increases with aging. The primary symptom is refractory joint pain accompanying with secondary muscle weakness and functional disability due to different mech
Externí odkaz:
http://ndltd.ncl.edu.tw/handle/79270473696463746329
Autor:
Ching-Chieh Chou, Ryan Vest, Miguel A. Prado, Joshua Wilson-Grady, Joao A. Paulo, Yohei Shibuya, Patricia Moran-Losada, Ting-Ting Lee, Jian Luo, Steven P. Gygi, Jeffery W. Kelly, Daniel Finley, Marius Wernig, Tony Wyss-Coray, Judith Frydman
Publikováno v:
bioRxiv
SummaryThe role of proteostasis and organelle homeostasis dysfunction in human aging and Alzheimer’s disease (AD) remains unclear. Analyzing proteome-wide changes in human donor fibroblasts and their corresponding transdifferentiated neurons (tNeur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ead7c3e080d4406b81646c2dbc08c497
https://europepmc.org/articles/PMC10081252/
https://europepmc.org/articles/PMC10081252/
Autor:
Ching‐Chieh Chou, Ryan Vest, Yohei Shibuya, Miguel A Prado, Joshua Wilson‐Grady, Michael D Greicius, Daniel Finley, Marius Wernig, Tony Wyss‐Coray, Judith Frydman
Publikováno v:
Alzheimer's & Dementia. 18
Autor:
Leonard Yoon, Rachel C. Botham, Adriaan Verhelle, Pablo Sanz-Martinez, Jin Xu, Christian M. Cole, Ee Phie Tan, Ching Chieh Chou, Caroline A. Cuoco, Lynée A. Massey, Sergio Labra, Lisa P. Elia, Amina Ta, Maziar S. Ardejani, Kyunga Lee, Gabriel M. Kline, Qiang Xiao, Sara Cano-Franco, Nora J. Lyang, William C. Hou, Anan Yu, Susan Fox, Yeonjin Ko, Cristian Wulkop-Gil, Lara H. Ibrahim, Starr Jiang, Alina Meneses, Luke T. Nelson, Hongfan Peng, Stuart A. Lipton, Michael J. Bollong, Malene Hansen, Richard I. Morimoto, H. Michael Petrassi, R. Luke Wiseman, Evan T. Powers, Steven Finkbeiner, Danny Garza, Daniel Finley, Miguel A. Prado, Ivan Dikic, Judith Frydman, Kristen A. Johnson, M. Catarina Silva, Stephen J. Haggarty, Alexandra Stolz, Sandra E. Encalada, Jeffery W. Kelly
SummaryAutophagy activation has the potential to ameliorate neurodegenerative disease phenotypes, including protein aggregation, lipid level perturbations and axonal trafficking defects. We performed a high content imaging-based screen assessing 940,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8e6dc4b0e683bc6167610911ea432da2
https://doi.org/10.1101/2022.09.29.509997
https://doi.org/10.1101/2022.09.29.509997
Autor:
Ryan T. Vest, Ching-Chieh Chou, Hui Zhang, Michael S. Haney, Lulin Li, Nouf N. Laqtom, Betty Chang, Steven Shuken, Andy Nguyen, Lakshmi Yerra, Andrew C. Yang, Carol Green, Mary Tanga, Monther Abu-Remaileh, Michael C. Bassik, Judith Frydman, Jian Luo, Tony Wyss-Coray
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, vol 119, iss 11
Significance Neurodegenerative diseases are poorly understood and difficult to treat. One common hallmark is lysosomal dysfunction leading to the accumulation of aggregates and other undegradable materials, which cause damage to brain resident cells.
Autor:
Vest, Ryan T., Ching-Chieh Chou, Hui Zhang, Haney, Michael S., Lulin Li, Laqtom, Nouf N., Chang, Betty, Shuken, Steven, Nguyen, Andy, Yerra, Lakshmi, Yang, Andrew C., Green, Carol, Tanga, Mary, Abu-Remaileh, Monther, Bassik, Michael C., Frydman, Judith, Jian Luo
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America; 3/15/2022, Vol. 119 Issue 11, p1-12, 30p