Zobrazeno 1 - 10
of 298
pro vyhledávání: '"Ching wen Chen"'
Publikováno v:
Frontiers in Neurology, Vol 14 (2023)
Patients with sickle cell anemia (SCA) have a high incidence of ischemic stroke, but are usually excluded from thrombolytic therapy due to concerns for cerebral hemorrhage. Maladaptation to cerebral ischemia may also contribute to the stroke propensi
Externí odkaz:
https://doaj.org/article/ac3a05be3369486fa9a1de11e2b7cc4f
Autor:
Guan-Yi He, Tai-Yi Hsu, Ching-Wen Chen, Feng-Jung Nien, Huan-Yuan Chen, Chia-Yu Chu, Li-Fang Wang
Publikováno v:
Acta Dermato-Venereologica, Vol 103 (2023)
Chronic pruritus is an unpleasant sensory perception that negatively affects quality of life and is common among patients with type 2 diabetes mellitus. Current antipruritic therapies are insufficiently effective. Thus, the mediation of diabetic prur
Externí odkaz:
https://doaj.org/article/4c110afc570849df9117cd0694d02809
Publikováno v:
Neurobiology of Disease, Vol 171, Iss , Pp 105802- (2022)
β-thalassemia is associated with multiple hematological and cerebrovascular symptoms linked to a hypercoagulable state that has not been fully replicated in animal models for the development of stroke treatments. Herein we compared the physiological
Externí odkaz:
https://doaj.org/article/ae3b17656d764c9f9e42d88b34263a5b
Autor:
Nathan J. Klingensmith, Katherine T. Fay, David A. Swift, Julia M.R. Bazzano, John D. Lyons, Ching-wen Chen, Mei Meng, Kimberly M. Ramonell, Zhe Liang, Eileen M. Burd, Charles A. Parkos, Mandy L. Ford, Craig M. Coopersmith
Publikováno v:
JCI Insight, Vol 7, Iss 16 (2022)
Expression of the tight junction–associated protein junctional adhesion molecule-A (JAM-A) is increased in sepsis, although the significance of this is unknown. Here, we show that septic JAM-A –/– mice have increased gut permeability, yet parad
Externí odkaz:
https://doaj.org/article/fbfc530dda6d4b10a3967d7271e7af69
Autor:
Ching-Wen Chen, Yuan-Hwa Chou, Ying-Jay Liou, Kai-Chun Yang, Li-Yu Hu, Wen-Chi Hsieh, Mu-N Liu
Publikováno v:
Journal of Psychiatric Research. 160:210-216
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b9718a52ae46bf48c9964c28080d6f0c
https://doi.org/10.1016/j.jpsychires.2023.02.015
https://doi.org/10.1016/j.jpsychires.2023.02.015
Autor:
Wenxiao Zhang, Jerome C. Anyalebechi, Kimberly M. Ramonell, Ching-wen Chen, Jianfeng Xie, Zhe Liang, Deena B. Chihade, Shunsuke Otani, Craig M. Coopersmith, Mandy L. Ford
Publikováno v:
JCI Insight, Vol 6, Iss 11 (2021)
TIGIT is a recently identified coinhibitory receptor that is upregulated in the setting of cancer and functionally contributes to the impairment of antitumor immunity. However, its role during sepsis is unknown. Because patients with cancer are 10 ti
Externí odkaz:
https://doaj.org/article/e3b4a1216da947ec9e12320f24aaca42
Autor:
Kristen N. Morrow, Zhe Liang, Ming Xue, Deena B. Chihade, Yini Sun, Ching-wen Chen, Craig M. Coopersmith, Mandy L. Ford
Publikováno v:
iScience, Vol 24, Iss 2, Pp 102093- (2021)
Summary: Sepsis is a leading cause of morbidity and mortality associated with significant impairment in memory T cells. These changes include the upregulation of co-inhibitory markers, a decrease in functionality, and an increase in apoptosis. Due to
Externí odkaz:
https://doaj.org/article/524248f651ff43ee98c877f6217ef49e
Brain-targeted hypoxia-inducible factor stabilization reduces neonatal hypoxic-ischemic brain injury
Autor:
Chia-Yi Kuan, Hong-Ru Chen, Ning Gao, Yi-Min Kuo, Ching-Wen Chen, Dianer Yang, Melissa M. Kinkaid, Erding Hu, Yu-Yo Sun
Publikováno v:
Neurobiology of Disease, Vol 148, Iss , Pp 105200- (2021)
Hypoxia-inducible factor-1α (HIF1α) is a major regulator of cellular adaptation to hypoxia and oxidative stress, and recent advances of prolyl-4-hydroxylase (P4H) inhibitors have produced powerful tools to stabilize HIF1α for clinical applications
Externí odkaz:
https://doaj.org/article/6456f2d7fc844e13bf4b231e4fc31136
Autor:
Deena B. Chihade, Prestina Smith, David A. Swift, Shunsuke Otani, Wenxiao Zhang, Ching-Wen Chen, Lauren A. Jeffers, Zhe Liang, Takashi Shimazui, Eileen M. Burd, Alton B. Farris, Bashar S. Staitieh, David M. Guidot, Mandy L. Ford, Michael Koval, Craig M. Coopersmith
Publikováno v:
Shock. 59:612-620
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9eefb79df6e797cdd76964fe7022ead6
https://doi.org/10.1097/shk.0000000000002081
https://doi.org/10.1097/shk.0000000000002081
Autor:
Takehiko Oami, Shabnam Abtahi, Takashi Shimazui, Ching-Wen Chen, Sweat, Yan Y., Zhe Liang, Burd, Eileen M., Farris, Alton B., Roland, Joe T., Sachiko Tsukita, Ford, Mandy L., Turner, Jerrold R., Coopersmith, Craig M.
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America; 3/5/2024, Vol. 121 Issue 10, p1-12, 32p