NF-κB promotes the stem-like properties of leukemia cells by activation of LIN28B.

Autor: Zhou J; Cancer Science Institute of Singapore, National University of Singapore, Singapore 117599, Singapore., Chooi JY; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 119074, Singapore., Ching YQ; Cancer Science Institute of Singapore, National University of Singapore, Singapore 117599, Singapore., Quah JY; Cancer Science Institute of Singapore, National University of Singapore, Singapore 117599, Singapore., Toh SH; Cancer Science Institute of Singapore, National University of Singapore, Singapore 117599, Singapore., Ng Y; Cancer Science Institute of Singapore, National University of Singapore, Singapore 117599, Singapore., Tan TZ; Cancer Science Institute of Singapore, National University of Singapore, Singapore 117599, Singapore., Chng WJ; Cancer Science Institute of Singapore, National University of Singapore, Singapore 117599, Singapore.

Publikováno v: World journal of stem cells [World J Stem Cells] 2018 Apr 26; Vol. 10 (4), pp. 34-42.

LIN28B Activation by PRL-3 Promotes Leukemogenesis and a Stem Cell-like Transcriptional Program in AML.

Autor: Zhou J; Cancer Science Institute of Singapore, National University of Singapore, Centre for Translational Medicine, Singapore, Republic of Singapore.; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Republic of Singapore., Chan ZL; Cancer Science Institute of Singapore, National University of Singapore, Centre for Translational Medicine, Singapore, Republic of Singapore., Bi C; Cancer Science Institute of Singapore, National University of Singapore, Centre for Translational Medicine, Singapore, Republic of Singapore., Lu X; Cancer Science Institute of Singapore, National University of Singapore, Centre for Translational Medicine, Singapore, Republic of Singapore., Chong PS; Cancer Science Institute of Singapore, National University of Singapore, Centre for Translational Medicine, Singapore, Republic of Singapore., Chooi JY; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Republic of Singapore., Cheong LL; Cancer Science Institute of Singapore, National University of Singapore, Centre for Translational Medicine, Singapore, Republic of Singapore., Liu SC; Cancer Science Institute of Singapore, National University of Singapore, Centre for Translational Medicine, Singapore, Republic of Singapore., Ching YQ; Cancer Science Institute of Singapore, National University of Singapore, Centre for Translational Medicine, Singapore, Republic of Singapore., Zhou Y; Cancer Science Institute of Singapore, National University of Singapore, Centre for Translational Medicine, Singapore, Republic of Singapore., Osato M; Cancer Science Institute of Singapore, National University of Singapore, Centre for Translational Medicine, Singapore, Republic of Singapore., Tan TZ; Cancer Science Institute of Singapore, National University of Singapore, Centre for Translational Medicine, Singapore, Republic of Singapore., Ng CH; Department of Haematology-Oncology, National University Cancer Institute, NUHS, Singapore, Republic of Singapore., Ng SB; Cancer Science Institute of Singapore, National University of Singapore, Centre for Translational Medicine, Singapore, Republic of Singapore.; Department of Pathology, National University Hospital, Singapore, Republic of Singapore.; Department of Pathology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore., Wang S; Department of Pathology, National University Hospital, National University Health System, Singapore., Zeng Q; Institute of Molecular and Cell Biology, A*STAR (Agency for Science, Technology and Research), Singapore, Republic of Singapore., Chng WJ; Cancer Science Institute of Singapore, National University of Singapore, Centre for Translational Medicine, Singapore, Republic of Singapore. mdccwj@nus.edu.sg.; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Republic of Singapore.; Department of Haematology-Oncology, National University Cancer Institute, NUHS, Singapore, Republic of Singapore.

Publikováno v: Molecular cancer research : MCR [Mol Cancer Res] 2017 Mar; Vol. 15 (3), pp. 294-303. Date of Electronic Publication: 2016 Dec 23.