Výsledky vyhledávání - "Ching Tien Lee"

Akademický článek

SGLT2 Inhibitor Canagliflozin Alleviates High Glucose-Induced Inflammatory Toxicity in BV-2 Microglia

Autor: Ching-Tien Lee, Kun-Der Lin, Cheng-Fang Hsieh, Jiz-Yuh Wang

Publikováno v: Biomedicines, Vol 12, Iss 1, p 36 (2023)

Patients with diabetes mellitus can experience hyperglycemia, which affects brain function and produces cognitive impairment or neurodegeneration. Neuroinflammation is an important cause of cognitive dysfunction. Sodium-glucose cotransporter 2 (SGLT2

Externí odkaz: https://doaj.org/article/60642363a8ea4baaadaf654d839c9342

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Bisphenol a Induces Autophagy Defects and AIF-Dependent Apoptosis via HO-1 and AMPK to Degenerate N2a Neurons

Autor: Jiz-Yuh Wang, Ching-Tien Lee, Cheng-Fang Hsieh

Publikováno v: International Journal of Molecular Sciences, Vol 22, Iss 10948, p 10948 (2021)
International Journal of Molecular Sciences
Volume 22
Issue 20

Bisphenol A (BPA) is an environmental contaminant widely suspected to be a neurological toxicant. Epidemiological studies have demonstrated close links between BPA exposure, pathogenetic brain degeneration, and altered neurobehaviors, considering BPA

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d08a16dc1902d75094959e6f3958e932
https://www.mdpi.com/1422-0067/22/20/10948

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1,25-Dihydroxyvitamin D3 modulates the effects of sublethal BPA on mitochondrial function via activating PI3K-Akt pathway and 17β-estradiol secretion in rat granulosa cells

Autor: Jiz Yuh Wang, Ching Tien Lee, Ming I. Hsu, Kuang Yi Chou

Publikováno v: The Journal of Steroid Biochemistry and Molecular Biology. 185:200-211

Bisphenol A (BPA), an endocrine-disrupting chemical, is capable of producing reproductive toxicity. BPA results in mitochondrial DNA (mtDNA) deletion and mitochondrial dysfunction; however, the effect of BPA on the mitochondria of ovarian granulosa c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2cf1001ba650e870790ed32394ce16f8
https://doi.org/10.1016/j.jsbmb.2018.09.002

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Acute glucose fluctuation impacts microglial activity, leading to inflammatory activation or self-degradation

Autor: Ching-Tien Lee, Cheng-Fang Hsieh, Ching-Kuan Liu, Liang-En Yu, Jiz-Yuh Wang

Publikováno v: Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-16 (2019)

Diabetes mellitus is associated with an increased risk of Alzheimer’s dementia and cognitive decline. The cause of neurodegeneration in chronic diabetic patients remains unclear. Changes in brain microglial activity due to glycemic fluctuations may

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b587dec366daf5ac652dfd6bf93758e0
http://europepmc.org/articles/PMC6351546

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1,25-Dihydroxyvitamin D

Autor: Ching-Tien, Lee, Jiz-Yuh, Wang, Kuang-Yi, Chou, Ming-I, Hsu

Publikováno v: The Journal of steroid biochemistry and molecular biology. 185

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::efbe269966a3f4476876313e08ab2ae0
https://pubmed.ncbi.nlm.nih.gov/30194976

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Akademický článek

1,25-Dihydroxyvitamin D3 increases testosterone-induced 17beta-estradiol secretion and reverses testosterone-reduced connexin 43 in rat granulosa cells.

Autor: Ching-Tien Lee¹, Jiz-Yuh Wang², Kuang-Yi Chou³, Ming-I Hsu⁴ hsumingi@yahoo.com.tw

Publikováno v: Reproductive Biology & Endocrinology. 9/20/2014, Vol. 12, p1-12. 12p.

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Electronegative Low-Density Lipoprotein L5 Impairs Viability and NGF-Induced Neuronal Differentiation of PC12 Cells via LOX-1

Autor: Chen-Yen Lin, Chiou-Lian Lai, Ching-Tien Lee, Jiz-Yuh Wang

Publikováno v: International Journal of Molecular Sciences, Vol 18, Iss 8, p 1744 (2017)
International Journal of Molecular Sciences
International Journal of Molecular Sciences; Volume 18; Issue 8; Pages: 1744

There have been striking associations of cardiovascular diseases (e.g., atherosclerosis) and hypercholesterolemia with increased risk of neurodegeneration including Alzheimer’s disease (AD). Low-density lipoprotein (LDL), a cardiovascular risk fact

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9cfb54eb3f17182d4f8b80a29fb73293
https://www.mdpi.com/1422-0067/18/8/1744

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Highly electronegative low-density lipoprotein L5 evokes microglial activation and creates a neuroinflammatory stress via Toll-like receptor 4 signaling

Autor: Liang-En Yu, Jiz-Yuh Wang, Ching-Tien Lee, Chiou-Lian Lai

Publikováno v: Journal of neurochemistry. 142(2)

Atherogenic risk factors, such as hypercholesterolemia, are associated with increased risk of neurodegeneration, especially Alzheimer's dementia. Human plasma electronegative low-density lipoprotein [LDL(-)], especially L5, may serve as an important

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e18c69d89bf4b1a3173f13b90f14725
https://pubmed.ncbi.nlm.nih.gov/28444734

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Widely Applicable Synthesis of Enantiomerically Pure Tertiary Alkyl-Containing 1-Alkanols by Zirconium-Catalyzed Asymmetric Carboalumination of Alkenes and Palladium- or Copper-Catalyzed Cross-Coupling

Autor: Ching-Tien Lee, Shiqing Xu, Ei-ichi Negishi, Guangwei Wang

Publikováno v: Chemistry - An Asian Journal. 8:1829-1835

A highly enantioselective and widely applicable method for the synthesis of various chiral 2-alkyl-1-alkanols, especially those of feeble chirality, has been developed. It consists of zirconium-catalyzed asymmetric carboalumination of alkenes (ZACA),

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::bd85623d262faa82c4d39a5aaefcf7d0
https://doi.org/10.1002/asia.201300311

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