Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Ching Serena Kao"'
Autor:
Ching Serena Kao, Rebekah van Bruggen, Jihye Rachel Kim, Xiao Xiao Lily Chen, Cadia Chan, Jooyun Lee, Woo In Cho, Melody Zhao, Claudia Arndt, Katarina Maksimovic, Mashiat Khan, Qiumin Tan, Michael D. Wilson, Jeehye Park
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-17 (2020)
MATR3 is an ALS-linked gene. Here the authors describe a mutant MATR3 knockin mouse, which mimics some aspects of early-stage ALS.
Externí odkaz:
https://doaj.org/article/0a3728efa1014765b5026bca91c3ff8d
Autor:
Xiao Xiao Lily Chen, Justin You, Jihye Rachel Kim, Rebekah van Bruggen, Ching Serena Kao, Hyeok Jun Lee, Mashiat Khan, David Duc Tran, Wooin Cho, Katarina Maksimovic, Jeehye Park
Publikováno v:
Biochemical and Biophysical Research Communications. 568:48-54
The F115C mutation in the MATR3 gene has been linked to amyotrophic lateral sclerosis (ALS). To determine the pathogenicity of the F115C mutation and the mechanism by which this mutation causes ALS, we generated mice that harbor the F115C mutation in
Autor:
Mashiat Khan, Xiao Xiao Lily Chen, Jooyun Lee, Qiumin Tan, Michael D. Wilson, Claudia Arndt, Jihye Rachel Kim, Jeehye Park, Rebekah van Bruggen, Ching Serena Kao, Melody Zhao, Cadia Chan, Woo In Cho, Katarina Maksimovic
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-17 (2020)
Nature Communications
Nature Communications
A missense mutation, S85C, in the MATR3 gene is a genetic cause for amyotrophic lateral sclerosis (ALS). It is unclear how the S85C mutation affects MATR3 function and contributes to disease. Here, we develop a mouse model that harbors the S85C mutat
Autor:
Jihye Rachel Kim, Katarina Maksimovic, Jooyun Lee, Xiao Xiao Lily Chen, Hongxian Zhu, Julia Qiao, Mashiat Khan, Melody Zhao, Wan Hee Yoon, David Duc Tran, Claudia Arndt, Deanna Kim, Woo In Cho, Rebekah van Bruggen, Jialu Xu, Jeehye Park, Jingyao Hong, Kailong Peng, Ching Serena Kao
Publikováno v:
FEBS lettersReferences. 594(17)
Mutations in the nuclear matrix protein Matrin 3 (MATR3) have been identified in amyotrophic lateral sclerosis and myopathy. To investigate the mechanisms underlying MATR3 mutations in neuromuscular diseases and efficiently screen for modifiers of MA