Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Ching Kuang Chuang"'
Autor:
Yi-Wen Chen, Shih-Yeh Lin, Chia-Hsin Lu, Chia-Hui Chen, Chia-Che Ho, Meng-Han Shen, Ching-Kuang Chuang
Publikováno v:
Int Wound J
The use of haemostatic agents can provide life-saving treatment for patients who suffer from massive bleeding in both prehospital and intraoperative conditions. However, there are still urgent demands for novel haemostatic materials that exhibit bett
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ca0136c4e5b3492175481e215361c7a
https://europepmc.org/articles/PMC7949266/
https://europepmc.org/articles/PMC7949266/
Autor:
Yu-Chen Hu, Chi-Yuan Chen, Wen Hsin Lo, Guan-Yu Chen, Hsiao Chiao Shiah, Yung-Jen Chuang, Jie Len Huang, Ching Kuang Chuang, Hung Ju Su, Shiaw-Min Hwang
Publikováno v:
Journal of Virology. 83:10548-10556
Human mesenchymal stem cells (hMSCs) can be genetically modified with viral vectors and hold promise as a cell source for regenerative medicine, yet how hMSCs respond to viral vector transduction remains poorly understood, leaving the safety concerns
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34b035dcb6c253436fce5f2f6f7f4dbf
https://doi.org/10.1128/jvi.01250-09
https://doi.org/10.1128/jvi.01250-09
Autor:
Yu-Chen Hu, Yu-Han Chang, Yao-Horng Wang, Huang-Chi Chen, Chin-Yu Lin, Ching-Kuang Chuang, Li-Yu Sung
Publikováno v:
Biomaterials. 30:674-681
Baculovirus has emerged as a promising gene delivery vector. Hereby de-differentiated rabbit chondrocytes were transduced ex vivo with a recombinant baculovirus expressing BMP-2 (Bac-CB), seeded to scaffolds and cultured statically for 1 day (Bac-w0
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b956f8bf494a86da3fc249cfed3bce79
https://doi.org/10.1016/j.biomaterials.2008.10.017
https://doi.org/10.1016/j.biomaterials.2008.10.017
Publikováno v:
Biotechnology and Bioengineering. 101:821-830
Co-conjugating chondroitin-6-sulfate (CSC) and dermatan sulfate (DS) to chitosan scaffolds improves chondrocyte differentiation and extracellular matrix (ECM) production. To further elucidate the cellular responses to CSC/DS conjugation, gene express
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f489065d24bfa2dfb9922a1c750467f6
https://doi.org/10.1002/bit.21953
https://doi.org/10.1002/bit.21953
Publikováno v:
Gene Therapy. 15:309-317
Baculovirus is an emerging gene delivery vector, thanks to a number of unique advantages. Herein, we genetically modified the rabbit articular chondrocytes with a recombinant baculovirus (Bac-CB) encoding bone morphogenetic protein-2 (BMP-2), which c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3791e41959b00a00f2c1a9c6276e10ab
https://doi.org/10.1038/sj.gt.3303087
https://doi.org/10.1038/sj.gt.3303087
Autor:
Tzu-Chen Yen, Chin-Yu Lin, Kun-Ju Lin, Li-Yu Sung, Ching-Kuang Chuang, Yu-Han Chang, Huang-Chi Chen, Shiaw-Min Hwang, Yu-Chen Hu
Publikováno v:
Tissue engineering. Part A. 16(2)
Baculovirus efficiently transduces human mesenchymal stem cells (hMSCs) and transplantation of hMSCs transduced with a bone morphogenetic protein 2-expressing baculovirus (Bac-CB) into nude mice results in ectopic bone formation. To attest the clinic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b96b4c9feccd21cf3d39d2b30e45a9b6
https://pubmed.ncbi.nlm.nih.gov/19702514
https://pubmed.ncbi.nlm.nih.gov/19702514
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 515
Mesenchymal stem cells (MSCs) have drawn considerable attention as vehicles for cell- and gene-based therapies. Additionally, baculovirus has emerged as a novel gene therapy vector because of its large cloning capacity for insertion of multiple genes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::09f2f0c8078e838e6d466dae721a98e7
https://pubmed.ncbi.nlm.nih.gov/19378120
https://pubmed.ncbi.nlm.nih.gov/19378120
Autor:
Tong Hong Wong, Yung Chung Chiu, Ching Kuang Chuang, Shiaw-Min Hwang, Guan-Yu Chen, Yu-Chen Hu, Yu Han Chang, Shiu Feng Huang
Publikováno v:
Molecular therapy : the journal of the American Society of Gene Therapy. 17(5)
Baculovirus holds great promise for the genetic modification of mesenchymal stem cells (MSCs). However, whether baculovirus transduction provokes undesired MSCs responses that might compromise their in vivo applications has yet to be examined. Hereby
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4040da8db090deef92e64d08166f7437
https://pubmed.ncbi.nlm.nih.gov/19277010
https://pubmed.ncbi.nlm.nih.gov/19277010
Baculovirus is a promising gene delivery vector but its widespread application is impeded as it only mediates transient transgene expression in mammalian cells. To prolong the expression, we developed a dual baculovirus system whereby one baculovirus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6369a2db1d2809bfe8fb6c5e3563f909
https://europepmc.org/articles/PMC2835104/
https://europepmc.org/articles/PMC2835104/
Autor:
Takayuki Abe, Yoshiharu Matsuura, Yen-Lin Chen, Shiaw-Min Hwang, Huang-Chi Chen, Yu-Chen Hu, Hsiao-Chiao Shiah, Hsiao-Ping Lee, Ching-Kuang Chuang
Publikováno v:
The journal of gene medicine. 11(4)
Background Baculovirus is an effective vector for gene delivery into primary chondrocytes and repeated baculovirus transduction (i.e. supertransduction) appears to be promising for prolonging transgene expression, but how supertransduction may influe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::780b17309bae67b537ed6b4abad959c7
https://pubmed.ncbi.nlm.nih.gov/19194979
https://pubmed.ncbi.nlm.nih.gov/19194979