Zobrazeno 1 - 10
of 204
pro vyhledávání: '"Ching Chuan, Kuo"'
Autor:
Chih-Peng Lin, Shu-Hui Wu, Tzu-Yin Lin, Chia-Hui Chu, Leu-Wei Lo, Ching-Chuan Kuo, Jang-Yang Chang, Szu-Chun Hsu, Bor-Sheng Ko, Ming Yao, Jong-Kai Hsiao, Shih-Wei Wang, Dong-Ming Huang
Publikováno v:
Pharmacological Research, Vol 197, Iss , Pp 106945- (2023)
Multidrug resistance (MDR) is a major challenge in cancer chemotherapy. Nanoparticles as drug delivery systems (DDSs) show promise for MDR cancer therapy. However, current DDSs require sophisticated design and construction based on xenogeneic nanomat
Externí odkaz:
https://doaj.org/article/86f572430e7749389f8fa9beb3b0a6e4
Autor:
Shine-Gwo Shiah, Jenn-Ren Hsiao, Hsiao-Ju Chang, Yuan-Ming Hsu, Guan-Hsun Wu, Hsuan-Yu Peng, Sung-Tau Chou, Ching-Chuan Kuo, Jang-Yang Chang
Publikováno v:
Journal of Biomedical Science, Vol 27, Iss 1, Pp 1-13 (2020)
Abstract Background Epigenetic silencing of retinoic acid (RA) signaling-related genes have been linked with the pathogenesis and clinical outcome in oral squamous cell carcinoma (OSCC) carcinogenesis. However, the precise mechanisms underlying the a
Externí odkaz:
https://doaj.org/article/8eb2b9f459944aa48d0ec169c427c2d6
Publikováno v:
Frontiers in Nutrition, Vol 8 (2022)
Sleep disturbances have been the hallmark of the recent coronavirus disease 2019 pandemic. Studies have shown that once sleep is disrupted, it can lead to psychological and physical health issues which can, in turn, disrupt circadian rhythm and induc
Externí odkaz:
https://doaj.org/article/edbf2dcb2ee6467c92b2a2f61993c36a
Autor:
Wen‐Jui Lee, Li‐Ching Chen, Juo‐Han Lin, Tzu‐Chun Cheng, Ching‐Chuan Kuo, Chih‐Hsiung Wu, Hui‐Wen Chang, Shih‐Hsin Tu, Yuan‐Soon Ho
Publikováno v:
Cancer Medicine, Vol 8, Iss 10, Pp 4821-4835 (2019)
Abstract Neuroblastoma is the second most common pediatric malignancy and has a high rate of spontaneous remission. Uncovering the mechanisms underlying neuroblastoma cell differentiation is critical for therapeutic purposes. A neuroblastoma cell lin
Externí odkaz:
https://doaj.org/article/7db11a9223b44eb8bb62dcd816d0ed33
Publikováno v:
Journal of Biomedical Science, Vol 25, Iss 1, Pp 1-12 (2018)
Abstract Background Tumor hypoxia-induced epithelial–mesenchymal transition (EMT) is critical in promoting cancer metastasis. We recently discovered a novel microtubule inhibitor, MPT0B098, that employs a novel antitumor mechanism. It destabilizes
Externí odkaz:
https://doaj.org/article/e22f493fa73243738f5e15e66b8f8542
Autor:
Wen-Jui Lee, Shih-Hsin Tu, Tzu-Chun Cheng, Juo-Han Lin, Ming-Thau Sheu, Ching-Chuan Kuo, Chun A. Changou, Chih-Hsiung Wu, Hui-Wen Chang, Hang-Lung Chang, Li-Ching Chen, Yuan-Soon Ho
Publikováno v:
Molecules, Vol 26, Iss 21, p 6548 (2021)
The microenvironment for tumor growth and developing metastasis should be essential. This study demonstrated that the hyaluronic acid synthase 3 (HAS3) protein and its enzymatic product hyaluronic acid (HA) encompassed in the subcutaneous extracellul
Externí odkaz:
https://doaj.org/article/75da9fb660f848f9a5d1943f57c0c831
Autor:
Jang-Yang Chang, Joseph T. Tseng, Wen-Yu Pan, Chi-Yen Chang, Kuang-Hsing Shih, Wen-Yang Lai, Ching-Chuan Kuo, Jing-Ping Liou, Yun-Ching Cheng
PDF - 361KB, Supplementary Materials and Methods; Table S1: Primary Antibodies and secondary antibodies; Figure S1: Effect of MPT0B098 on the organizations of cellular microtubule network; Figure S2: Effect of MPT0B098 on HIF-regulated genes in A549
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29fb24acf00ae07d78376bd6c9f218e4
https://doi.org/10.1158/1535-7163.22500639.v1
https://doi.org/10.1158/1535-7163.22500639.v1
Autor:
Jang-Yang Chang, Joseph T. Tseng, Wen-Yu Pan, Chi-Yen Chang, Kuang-Hsing Shih, Wen-Yang Lai, Ching-Chuan Kuo, Jing-Ping Liou, Yun-Ching Cheng
Microtubule inhibitors have been shown to inhibit hypoxia-inducible factor-1α (HIF-1α) expression through inhibition translation or enhancing protein degradation. Little is known of the effect of microtubule inhibitors on the stability of HIF-1α m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::218640820bf2f6bca3353fa3d414cc67
https://doi.org/10.1158/1535-7163.c.6536526.v1
https://doi.org/10.1158/1535-7163.c.6536526.v1
Autor:
Shaw-Jenq Tsai, H. Sunny Sun, Yi-Min Liu, Ching-Chuan Kuo, Jang-Yang Chang, Jing-Ping Liou, Bo-Wen Lin, Jenq-Chang Lee, Shau-Chieh Lin, Shih-Chieh Lin, Yo-Hua Li, Pei-Chi Hou
Loss-of-DUSP2 results in the expansion of CSC-like population.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::900d234e2cc544490235443f12ca75d0
https://doi.org/10.1158/0008-5472.22414251
https://doi.org/10.1158/0008-5472.22414251
Autor:
Shaw-Jenq Tsai, H. Sunny Sun, Yi-Min Liu, Ching-Chuan Kuo, Jang-Yang Chang, Jing-Ping Liou, Bo-Wen Lin, Jenq-Chang Lee, Shau-Chieh Lin, Shih-Chieh Lin, Yo-Hua Li, Pei-Chi Hou
Table S1. CSC frequency measured by ELDA in vitro. Table S2. Multiple corrections for correlation p value. Table S3. Tumor incidence in limiting dilution assay (I). Table S4. Tumor incidence in limiting dilution assay (II). Table S5. Top 10 list of c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bee29190bccc759e203987712b190ea
https://doi.org/10.1158/0008-5472.22414230.v1
https://doi.org/10.1158/0008-5472.22414230.v1