Výsledky vyhledávání - "Ching Chiu Liu"

Data from The Kringle 1 Domain of Hepatocyte Growth Factor Has Antiangiogenic and Antitumor Cell Effects on Hepatocellular Carcinoma

Autor: Marie C.M. Lin, Hsiang Fu Kung, Ming Liang He, Ren Bao Gan, Tsai Ping Li, Kong Hung Sze, John M. Luk, Sheung Tat Fan, Ronnie T.P. Poon, Ching Chiu Liu, Hai Xiao Chen, Ji Cheng Li, Yi Gao, Zhen Fan Yang, Zan Shen

The kringle 1 domain of human hepatocyte growth factor (HGFK1) was previously shown to inhibit bovine aortic endothelial cell proliferation, suggesting that it might be an antiangiogenic molecule. Here, we evaluated the in vivo efficacy of a recombin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8aacba587800cf4db7cad4750453c4b7
https://doi.org/10.1158/0008-5472.c.6497469

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Hepatocyte nuclear factor 1 binding element within the promoter of microsomal triglyceride transfer protein (MTTP) gene is crucial for MTTP basal expression and insulin responsiveness

Autor: WS Au, Chung-Man Yeung, Liwei Lu, Marie C. Lin, Lihui Lai, Oscar G.W. Wong, Hsiang-Fu Kung, Ching-Chiu Liu

Publikováno v: Journal of Molecular Endocrinology. 41:229-238

Insulin inhibits the transcription of the microsomal triglyceride transfer protein (MTTP), which plays a pivotal role in lipoprotein assembly and secretion. Here, we provide evidence that a hepatocyte nuclear factor 1 binding element (HNF1A element)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d1211dd416efdc41315b7c7a3a71d86
https://doi.org/10.1677/jme-08-0080

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Pluronic L-81 ameliorates diabetic symptoms in db/db mice through transcriptional regulation of microsomal triglyceride transfer protein

Autor: WS Au, Chung-Man Yeung, Otis King Hung Ko, Ming-Liang He, Samuel S. Ng, Marie C. Lin, Liwei Lu, Billy K. C. Chow, Ching-Chiu Liu, Sidney Tam, Hsiang-Fu Kung

Aim: To test whether oral L-81 treatment could improve the condition of mice with diabetes and to investigate how L-81 regulates microsomal triglyceride transfer protein (MTP) activity in the liver. Methods: Genetically diabetic (db/db) mice were fed

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6c6152147eef8b1b2c516ff12dee8da
https://europepmc.org/articles/PMC2702106/

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The kringle 1 domain of hepatocyte growth factor has antiangiogenic and antitumor cell effects on hepatocellular carcinoma

Autor: John M. Luk, Ronnie T.P. Poon, Hsiang-Fu Kung, Tsai Ping Li, Marie C.M. Lin, Yi Gao, Ren Bao Gan, Ming-Liang He, Kong-Hung Sze, Zhen Fan Yang, Zan Shen, Ji-Cheng Li, Hai Xiao Chen, Sheung Tat Fan, Ching Chiu Liu

Publikováno v: Cancer research. 68(2)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34bff248aca06ffb4c7ccc824ce64df8
https://pubmed.ncbi.nlm.nih.gov/18199534

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Cancer gene therapy targeting angiogenesis: An updated review

Autor: Zan Shen, Marie C.M. Lin, Hsiang-Fu Kung, Ching-Chiu Liu

Since the relationship between angiogenesis and tumor growth was established by Folkman in 1971, scientists have made efforts exploring the possibilities in treating cancer by targeting angiogenesis. Inhibition of angiogenesis growth factors and admi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74dc3d0249cbb2cba11f72d1da14571a
http://hdl.handle.net/10722/68864

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293. Sustained Expression of Kringle 1 Domain of Human Hepatocyte Growth Factor (HGFK1) Effectively Inhibits Angiogenesis, Growth and Metastasis of Hepatocellular Carcinoma

Autor: Tsai-ping Li, Ching Chiu Liu, Hsiang-Fu Kung, Ming-Liang He, Marie Chia-mi Lin, Yi Gao, Samuel S. Ng, Zan Shen, Ren-bao Gan, Sheung Tat Fan, Zhen Fan Yang

Publikováno v: Molecular Therapy. 13:S111-S112

We have previously shown that recombinant protein of kringle 1 domain of human hepatocyte growth factor (HGFK1) exhibits anti- angiogenesis activity. Here we investigated the in vivo therapeutic effect of long term expression of HGFK1 on hepatocellul

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb6ad982a4061ab185ae7c0882572431

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