Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Chinelo D Ezeonwuka"'
Autor:
Carl O Olson, Robby M Zachariah, Chinelo D Ezeonwuka, Vichithra R B Liyanage, Mojgan Rastegar
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e90645 (2014)
MeCP2 is a critical epigenetic regulator in brain and its abnormal expression or compromised function leads to a spectrum of neurological disorders including Rett Syndrome and autism. Altered expression of the two MeCP2 isoforms, MeCP2E1 and MeCP2E2
Externí odkaz:
https://doaj.org/article/047f4ba6b42345e188dbaa95e4f78880
Autor:
Chinelo D. Ezeonwuka, Mojgan Rastegar
Publikováno v:
Diseases, Vol 2, Iss 1, Pp 45-70 (2014)
The role of epigenetics in human disease has become an area of increased research interest. Collaborative efforts from scientists and clinicians have led to a better understanding of the molecular mechanisms by which epigenetic regulation is involved
Externí odkaz:
https://doaj.org/article/5fd3d29407d34817999adddb10c272cc
Publikováno v:
PLoS ONE, Vol 7, Iss 11, p e49763 (2012)
PLoS ONE
PLoS ONE
Rett Syndrome (RTT) is a severe neurological disorder in young females, and is caused by mutations in the X-linked MECP2 gene. MECP2/Mecp2 gene encodes for two protein isoforms; MeCP2E1 and MeCP2E2 that are identical except for the N-terminus region
Autor:
Vichithra R. B. Liyanage, Carl O. Olson, Mojgan Rastegar, Robby M. Zachariah, Chinelo D. Ezeonwuka
Publikováno v:
PLoS ONE
PLoS ONE, Vol 9, Iss 3, p e90645 (2014)
PLoS ONE, Vol 9, Iss 3, p e90645 (2014)
MeCP2 is a critical epigenetic regulator in brain and its abnormal expression or compromised function leads to a spectrum of neurological disorders including Rett Syndrome and autism. Altered expression of the two MeCP2 isoforms, MeCP2E1 and MeCP2E2