Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Chinedu A. Ezekekwu"'
Autor:
Henry O. Ebili, Sebastian A. Omenai, Uchenna S. Ezenkwa, Ayotunde O. Ale, Patrick A. Akintola, Adesoji E. Adetona, Chima U. Akunwata, Mbwas I. Mashor, Ifeanyichukwu D. Nwanji, Oluwadamilare Iyapo, Chinedu A. Ezekekwu, John C. Akulue, Ngozi Chidozie
Publikováno v:
Annals of Urologic Oncology (2024)
Background The clinicopathological significance of KRAS alterations in clinical prostate cancer (PCa) has yet to be comprehensively studied, and the classic KRAS somatic mutations are rare in PCa. Methods The clinico-genomic data of two PCa cohorts
Externí odkaz:
https://doaj.org/article/30a01abc6dec4cafb77b7cd47d49f5d6
Autor:
Santosh L. Saraf, Titilola S. Akingbola, Binal N. Shah, Chinedu A. Ezekekwu, Omowunmi Sonubi, Xu Zhang, Lewis L. Hsu, Mark T. Gladwin, Roberto F. Machado, Richard S. Cooper, Victor R. Gordeuk, Bamidele O. Tayo
Publikováno v:
Blood Advances, Vol 1, Iss 11, Pp 693-698 (2017)
Abstract: α-Thalassemia and the BCL11A rs1427407 T allele are commonly observed in sickle cell anemia (SCA) patients and are associated with reduced hemolysis and higher hemoglobin F levels, respectively. We investigated whether a high-risk genetic
Externí odkaz:
https://doaj.org/article/e9e2897c2597416d93ab508448e3005a
Autor:
Bamidele O. Tayo, Titilola S. Akingbola, Chinedu A Ezekekwu, Kotila Tr, Chinonso Chiemeka Anyanwu-Yeiya
Publikováno v:
Blood. 138:4261-4261
Introduction Among the risk factors for venous thromboembolism (VTE) are inheritance of the sickle cell gene and antiphospholipid syndrome. Antiphospholipid antibodies are elevated in sickle cell disease but there is little information on its levels
Autor:
Omowunmi Sonubi, Lewis L. Hsu, Santosh L. Saraf, Richard S. Cooper, Xu Zhang, Jin Han, Robert E. Molokie, Chinedu A. Ezekekwu, Bamidele O. Tayo, Victor R. Gordeuk, Titilola S. Akingbola
Publikováno v:
American Journal of Hematology. 94
Autor:
Lewis L. Hsu, Santosh L. Saraf, Victor R. Gordeuk, Titilola S. Akingbola, Omowunmi Sonubi, Chinedu A. Ezekekwu, Bamidele O. Tayo, Richard S. Cooper, Binal N. Shah
Publikováno v:
American Journal of Hematology. 93
Autor:
Kotila Tr, Chinedu A. Ezekekwu, Victor R. Gordeuk, Titilola S. Akingbola, Richard S. Cooper, Michael R. DeBaun, Guillaume Lettre, Bamidele O. Tayo, Baba Inusa
Publikováno v:
Journal of tropical diseases & public health
More recent evidence however suggests the likelihood of four independent mutations of the sickle cell gene in different populations; three of which occurred in Africa. The trans-Atlantic slave trade accounted for the gene movement from Africa to the
Autor:
Xu Zhang, Victor R. Gordeuk, Santosh L. Saraf, Mark T. Gladwin, Binal N. Shah, Lewis L. Hsu, Richard S. Cooper, Roberto F. Machado, Titilola S. Akingbola, Omowunmi Sonubi, Chinedu A. Ezekekwu, Bamidele O. Tayo
Publikováno v:
Blood advances. 1(11)
Alpha-thalassemia and the BCL11A rs1427407 T allele are commonly observed in sickle cell anemia (SCA) patients and are associated with reduced hemolysis and higher hemoglobin F levels, respectively. We investigated whether a high-risk genetic profile
Autor:
Richard S. Cooper, Titilola S. Akingbola, Lewis L. Hsu, Victor R. Gordeuk, Chinedu A. Ezekekwu, Bamidele O. Tayo, Omowunmi Sonubi, Santosh L. Saraf, Jin Han
Publikováno v:
Blood. 132:3656-3656
Background. Despite a large body of evidence that hydroxyurea is effective for sickle cell anemia (SCA), utilization with the "maximum tolerated dose" regimen has been low.1 Hydroxyurea therapy for SCA increases hemoglobin F, reduces pain crises, acu
Autor:
Omowunmi Sonubi, Bamidele O. Tayo, Santosh L. Saraf, Chinedu A. Ezekekwu, Richard S. Cooper, Victor R. Gordeuk, Binal N. Shah, Lewis L. Hsu, Titilola S. Akingbola
Publikováno v:
Blood. 130:981-981
Background: The vast majority of births with sickle cell anemia occur in Africa 1 and early-life mortality, generally before age five years, is as high as 90% 2,3. Hydroxyurea was approved for sickle cell anemia by the US FDA in 1998 but is not commo
Autor:
Victor R. Gordeuk, Joseph Yaria, Chinedu A. Ezekekwu, Lewis L. Hsu, Titilola S. Akingbola, Santosh L. Saraf, Richard S. Cooper, Bamidele O. Tayo
Publikováno v:
Blood. 126:4581-4581
Introduction: Chronic hemolysis occurs in sickle cell anemia as a result of recurrent sickling and other abnormalities of the red blood cells including eryptosis. Exuberant reticulocytosis is anticipated to partially compensate for the resultant anem