Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Chinedu A Anene"'
Autor:
Anca Tutuianu, Chinedu A Anene, Mikayla Shelton, Valerie Speirs, Donald C Whitelaw, Joanne Thorpe, Wayne Roberts, James R Boyne
Publikováno v:
PLoS ONE, Vol 19, Iss 6, p e0304870 (2024)
The underlying causes of breast cancer are diverse, however, there is a striking association between type 2 diabetes and poor patient outcomes. Platelet activation is a common feature of both type 2 diabetes and breast cancer and has been implicated
Externí odkaz:
https://doaj.org/article/6ce5d6597a2440babcf9c72ede1382a4
Publikováno v:
Frontiers in Genetics, Vol 13 (2022)
The assessment of the cellular heterogeneity and abundance in bulk tissue samples is essential for characterising cellular and organismal states. Computational approaches to estimate cellular abundance from bulk RNA-Seq datasets have variable perform
Externí odkaz:
https://doaj.org/article/1b0d46cce4604bedab09954cd91ec840
Publikováno v:
Patterns, Vol 2, Iss 6, Pp 100270- (2021)
Summary: Determining the tissue- and disease-specific circuit of biological pathways remains a fundamental goal of molecular biology. Many components of these biological pathways still remain unknown, hindering the full and accurate characterization
Externí odkaz:
https://doaj.org/article/14fe60e4a32f44c38631eb79c059e159
Autor:
Timothy J. Mottram, Katherine L. Harper, Elton J. R. Vasconcelos, Chinedu A. Anene, Adrian Whitehouse
Pseudouridylation is a prevalent RNA modification shown to occur in tRNAs, rRNAs, snoRNAs and most recently mRNAs and lncRNAs. Emerging evidence suggests that this dynamic RNA modification is implicated in altering gene expression by regulating RNA s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1d3923852eda02c05bcc76d6f2317c7d
https://doi.org/10.1101/2023.01.31.526461
https://doi.org/10.1101/2023.01.31.526461
Autor:
M. Shelton, Jérémie Nsengimana, Julia Newton-Bishop, James R. Boyne, Wayne Roberts, Chinedu Anthony Anene, O. Bi
Publikováno v:
Oncogene
The multifunctional protein, splicing factor, proline- and glutamine-rich (SFPQ) has been implicated in numerous cancers often due to interaction with coding and non-coding RNAs, however, its role in melanoma remains unclear. We report that knockdown
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f24d87e0109579882e4605da238bb5f8
http://europepmc.org/articles/PMC8376646
http://europepmc.org/articles/PMC8376646
HNRNPA2B1 controls an unfolded protein response-related prognostic gene signature in prostate cancer
Autor:
John G Foster, Esteban Gea, Mosammat A Labiba, Chinedu A Anene, Jacqui Stockley, Celine Philippe, Matteo Cereda, Kevin Rouault-Pierre, Hing Leung, Conrad Bessant, Prabhakar Rajan
HNRNPA2B1 is associated with prostate cancer (PC) disease aggressiveness and underlies pro-tumourigenic cellular stress responses. By analysing >500 PC transcriptomes, we reveal that HNRNPA2B1 over-expression is associated with poor patient prognosis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0bcf19dcb163884ad39dd79d34f8d52
http://hdl.handle.net/2434/932169
http://hdl.handle.net/2434/932169
Autor:
Katherine L Harper, Timothy J Mottram, Chinedu A Anene, Becky Foster, Molly R Patterson, Euan McDonnell, Andrew Macdonald, David Westhead, Adrian Whitehouse
Publikováno v:
EMBO reports. 23(5)
Non-coding RNA (ncRNA) regulatory networks are emerging as critical regulators of gene expression. These intricate networks of ncRNA:ncRNA interactions modulate multiple cellular pathways and impact the development and progression of multiple disease
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8d86a329018e109dd8d513206ebad7c
https://pubmed.ncbi.nlm.nih.gov/35239998
https://pubmed.ncbi.nlm.nih.gov/35239998
Autor:
David R. Westhead, Timothy James Mottram, Adrian Whitehouse, Chinedu A. Anene, Becky Foster, Euan McDonnell, Katherine L. Harper, Andrew Macdonald, Molly R. Patterson
Non-coding RNA (ncRNA) regulatory networks are emerging as critical regulators of gene expression. These intricate networks of ncRNA:ncRNA interactions modulate multiple cellular pathways and impact the development and progression of multiple disease
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5e0673d6ff6ee4e09735e4a6f59bb7c5
https://doi.org/10.1101/2021.10.07.463491
https://doi.org/10.1101/2021.10.07.463491
Autor:
James R. Boyne, M. Shelton, Wayne Roberts, Julia Newton-Bishop, Chinedu Anthony Anene, Jérémie Nsengimana
Publikováno v:
Biochimica et biophysica acta. Reviews on cancer. 1875(1)
Exosomes play a crucial role in the crosstalk between cancer associated fibroblasts (CAFs) and cancer cells, contributing to carcinogenesis and the tumour microenvironment. Recent studies have revealed that CAFs, normal fibroblasts and cancer cells a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c11356d881a31a25a95e9df81888657
https://pubmed.ncbi.nlm.nih.gov/33153973
https://pubmed.ncbi.nlm.nih.gov/33153973
Autor:
Gareth J. Inman, Irene M. Leigh, Jun Wang, Findlay Bewicke-Copley, Chinedu Anthony Anene, Jason Thomson, Catherine A. Harwood, Ai Nagano, Abha Gulati, Charlotte M. Proby, Karin J. Purdie
Publikováno v:
The Journal of investigative dermatology. 141(7)
Actinic keratoses (AKs) are lesions of epidermal keratinocyte dysplasia and are precursors for invasive cutaneous squamous cell carcinoma (cSCC). Identifying the specific genomic alterations driving the progression from normal skin to skin with AK to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35de0d3e2bd94f2f287f0646bd5192bc
https://pubmed.ncbi.nlm.nih.gov/34167719
https://pubmed.ncbi.nlm.nih.gov/34167719