Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Chinchu Jayaprakash"'
Autor:
Katarzyna B. Leszczynska, Amanda Freitas-Huhtamäki, Chinchu Jayaprakash, Monika Dzwigonska, Francisca N.L. Vitorino, Cynthia Horth, Kamil Wojnicki, Bartlomiej Gielniewski, Paulina Szadkowska, Beata Kaza, Javad Nazarian, Maciej K. Ciolkowski, Joanna Trubicka, Wieslawa Grajkowska, Benjamin A. Garcia, Jacek Majewski, Bozena Kaminska, Jakub Mieczkowski
Publikováno v:
Cell Reports, Vol 43, Iss 2, Pp 113707- (2024)
Summary: Diffuse intrinsic pontine gliomas (DIPGs) are deadly pediatric brain tumors, non-resectable due to brainstem localization and diffusive growth. Over 80% of DIPGs harbor a mutation in histone 3 (H3.3 or H3.1) resulting in a lysine-to-methioni
Externí odkaz:
https://doaj.org/article/590589af8239422c9bd340fc8f43c4fa
Publikováno v:
Frontiers in Genetics, Vol 12 (2021)
Somatic mutations in histone encoding genes result in gross alterations in the epigenetic landscape. Diffuse intrinsic pontine glioma (DIPG) is a pediatric high-grade glioma (pHGG) and one of the most challenging cancers to treat, with only 1% surviv
Externí odkaz:
https://doaj.org/article/55b82dcc1646435e83187b9eb9532133
Autor:
Katarzyna B. Leszczynska, Amanda Pereira de Freitas, Chinchu Jayaprakash, Monika Dzwigonska, Kamil Wojnicki, Bartlomiej Gielniewski, Paulina Szadkowska, Beata Kaza, Maciej K. Ciolkowski, Joanna Trubicka, Wieslawa Grajkowska, Bozena Kaminska, Jakub Mieczkowski
Diffuse intrinsic pontine gliomas (DIPG) are deadly paediatric brain tumours, non-resectable due to brainstem localisation and diffusive growth. Patients with DIPG have a dismal prognosis of 9-12 months of survival with no effective therapy. Over 80%
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e3036265b078a408741857b9b815d3d6
https://doi.org/10.1101/2023.05.15.540760
https://doi.org/10.1101/2023.05.15.540760
Publikováno v:
Frontiers in Genetics
Frontiers in Genetics, Vol 12 (2021)
Frontiers in Genetics, Vol 12 (2021)
Somatic mutations in histone encoding genes result in gross alterations in the epigenetic landscape. Diffuse intrinsic pontine glioma (DIPG) is a pediatric high-grade glioma (pHGG) and one of the most challenging cancers to treat, with only 1% surviv
Publikováno v:
Advances in experimental medicine and biology. 1202
Signal transduction pathways directly communicate and transform chromatin to change the epigenetic landscape and regulate gene expression. Chromatin acts as a dynamic platform of signal integration and storage. Histone modifications and alteration of
Publikováno v:
Advances in Experimental Medicine and Biology ISBN: 9783030306502
Signal transduction pathways directly communicate and transform chromatin to change the epigenetic landscape and regulate gene expression. Chromatin acts as a dynamic platform of signal integration and storage. Histone modifications and alteration of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4c2cec10fe0728879e1f24a8a6cb826b
https://doi.org/10.1007/978-3-030-30651-9_13
https://doi.org/10.1007/978-3-030-30651-9_13
Publikováno v:
Archives of Oral Biology. 80:197-208
The relevance of DNA methylation of OTo ascertain the significance of DNA methylation of MGMT promoter in oral squamous cell carcinoma (OSCC), we undertook a study to a) analyse the methylation patterns of MGMT gene promoter in afflicted and normal p
Autor:
Pradyumna Jayaram, Adarsh Kudva, Sanjiban Chakrabarty, Kapaettu Satyamoorthy, Chinchu Jayaprakash, Vinay Koshy Varghese, Satadru Ray
Publikováno v:
Journal of oral pathologymedicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral PathologyREFERENCES. 49(5)
Background Screening for lesions in the oral cavity is critical for early diagnosis of oral squamous cell carcinoma (OSCC). Targeted next generation sequencing-based (NGS) mutation analysis of cancer driver genes becomes a reality for personalized me
Autor:
Smitha Bhat, Melisa J. Andrade, Nikolaos Evangelatos, Kapaettu Satyamoorthy, Angela Brand, Chinchu Jayaprakash
Publikováno v:
Public health genomics. 20(5)
Antibiotics are the first line of treatment against infections and have contributed immensely to reduce the morbidity and mortality rates. Recently, extensive use of antibiotics has led to alterations of the gut microbiome, predisposition to various
Autor:
Samatha Bhat, Kapaettu Satyamoorthy, Raghu Radhakrishnan, Shama Prasada Kabekkodu, Satadru Ray, Chinchu Jayaprakash
Publikováno v:
Virchows Archiv : an international journal of pathology. 470(4)
The present study was undertaken to explore and validate novel hypermethylated DNA regions in squamous cell carcinoma of the tongue (SCCT). Genome-wide methylation changes were identified by differential methylation hybridization (DMH) microarray and