Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Chinatsu Otomo"'
Publikováno v:
eLife, Vol 8 (2019)
An enigmatic step in de novo formation of the autophagosome membrane compartment is the expansion of the precursor membrane phagophore, which requires the acquisition of lipids to serve as building blocks. Autophagy-related 2 (ATG2), the rod-shaped p
Externí odkaz:
https://doaj.org/article/9869c75356f348daad83c00143714e59
Publikováno v:
PLoS ONE, Vol 5, Iss 9 (2010)
Formin proteins utilize a conserved formin homology 2 (FH2) domain to nucleate new actin filaments. In mammalian diaphanous-related formins (DRFs) the FH2 domain is inhibited through an unknown mechanism by intramolecular binding of the diaphanous au
Externí odkaz:
https://doaj.org/article/8691cfdf88d84a81b7b50ccb8fecb892
Autor:
Zhifeng Chen, Bing Zhou, Cheng Luo, Junchi Hu, Chinatsu Otomo, Xie Yuli, Yongjun Dang, Liyan Yue, Yuanyuan Zhang, Lianchun Li, Naixia Zhang, Wei Wan, Junyan Lu, Hualiang Jiang, Takanori Otomo, Yi Wen, Quanfu Li, Lin Tingting, Hongru Tao, Zhiyi Yao, Hong Ding, Pan Xu, Mingrui Zhu, Bidong Zhang, Minjia Tan, Kaixian Chen, Shijie Fan
Publikováno v:
Angew Chem Int Ed Engl
The autophagic ubiquitin-like protein LC3 functions through interactions with LC3-interaction regions (LIRs) of other autophagy proteins, including autophagy receptors, which stands out as a promising protein-protein interaction (PPI) target for the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::208993b70ca522f483ad2e1adae36341
https://doi.org/10.1002/anie.202109464
https://doi.org/10.1002/anie.202109464
Autor:
Nick V. Grishin, Christina M. Garza, Stefano Forli, Chinatsu Otomo, Lisa N. Kinch, Satoru Takahashi, Noboru Mizushima, Shintaro Maeda, Hayashi Yamamoto, Takanori Otomo
Publikováno v:
Nature structural & molecular biology
De novo formation of the double-membrane compartment autophagosome is seeded by small vesicles carrying membrane protein autophagy-related 9 (ATG9), the function of which remains unknown. Here we find that ATG9A scrambles phospholipids of membranes i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::caf94f5e2432d850e6c8d03ba0409e1e
http://europepmc.org/articles/PMC7718406
http://europepmc.org/articles/PMC7718406
Publikováno v:
eLife, Vol 8 (2019)
An enigmatic step in de novo formation of the autophagosome membrane compartment is the expansion of the precursor membrane phagophore, which requires the acquisition of lipids to serve as building blocks. Autophagy-related 2 (ATG2), the rod-shaped p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a71688e423a45a269f6b4f476029c784
https://doi.org/10.1101/555441
https://doi.org/10.1101/555441
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1880
Members of the autophagy-related protein 8 (Atg8) family of ubiquitin-like proteins (ublps), including mammalian LC3 and GABARAP proteins, play crucial roles in autophagosome biogenesis, as well as selective autophagy. Upon induction of autophagy, th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a29e30946577a6597d7149aadc0e7c71
https://pubmed.ncbi.nlm.nih.gov/30610689
https://pubmed.ncbi.nlm.nih.gov/30610689
Publikováno v:
Methods in Molecular Biology ISBN: 9781493988723
Members of the autophagy-related protein 8 (Atg8) family of ubiquitin-like proteins (ublps), including mammalian LC3 and GABARAP proteins, play crucial roles in autophagosome biogenesis, as well as selective autophagy. Upon induction of autophagy, th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ce591bb46696f5337263876033871fd6
https://doi.org/10.1007/978-1-4939-8873-0_3
https://doi.org/10.1007/978-1-4939-8873-0_3
Autor:
Alexander Leitner, Saikat Chowdhury, Gabriel C. Lander, Kazuto Ohashi, Chinatsu Otomo, Takanori Otomo, Ruedi Aebersold
Publikováno v:
Proceedings of the National Academy of Sciences
Autophagy is an enigmatic cellular process in which double-membrane compartments, called autophagosomes, form de novo adjacent to the endoplasmic reticulum (ER) and package cytoplasmic contents for delivery to lysosomes. Expansion of the precursor me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee135cb7985031fe786db65c1559b5be
https://doi.org/10.1101/180315
https://doi.org/10.1101/180315
Publikováno v:
Proceedings of the National Academy of Sciences. 110:18844-18849
The autophagic ubiquitin-like protein (ublp) autophagy-related (ATG)12 is a component of the ATG12∼ATG5-ATG16L1 E3 complex that promotes lipid conjugation of members of the LC3 ublp family. A role of ATG12 in the E3 complex is to recruit the E2 enz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bdfb97c8d6ef81e3bfbdf7b95b1696c1
https://doi.org/10.1073/pnas.1314755110
https://doi.org/10.1073/pnas.1314755110