Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Chinatsu Kurasaka"'
Publikováno v:
FEBS Open Bio, Vol 13, Iss 6, Pp 1125-1133 (2023)
5‐Fluorouracil (5‐FU) is widely used for colorectal cancer (CRC) treatment; however, continuous treatment of CRC cells with 5‐FU can result in acquired resistance, and the underlying mechanism of 5‐FU resistance remains unclear. We previously
Externí odkaz:
https://doaj.org/article/bc448e2f819543bcb33321bb9f933131
Publikováno v:
FASEB BioAdvances, Vol 5, Iss 1, Pp 43-51 (2023)
Abstract 5‐Fluorouracil (5‐FU) is a cornerstone drug used to treat colorectal cancer (CRC). However, the prolonged exposure of CRC cells to 5‐FU results in acquired resistance. We have previously demonstrated that levels of the 5‐fluorodeoxyu
Externí odkaz:
https://doaj.org/article/15b6e319f65e485abb46ccb0d927b62d
Publikováno v:
ACS Omega, Vol 7, Iss 7, Pp 6046-6052 (2022)
Externí odkaz:
https://doaj.org/article/dd6129f5056e4ad892ded56f95fcdade
Publikováno v:
Cancer Reports, Vol 6, Iss 2, Pp n/a-n/a (2023)
Abstract Background Poly(ADP‐ribose) glycohydrolase (PARG) is a key enzyme in poly(ADP‐ribose) (PAR) metabolism and a potential anticancer target. Many drug candidates have been developed to inhibit its enzymatic activity. Additionally, PDD000172
Externí odkaz:
https://doaj.org/article/e84445096a35457abc37c84e8e9eeab3
Publikováno v:
FASEB BioAdvances. 5:43-51
Publikováno v:
Cancer Reports. 6
Poly(ADP-ribose) glycohydrolase (PARG) is a key enzyme in poly(ADP-ribose) (PAR) metabolism and a potential anticancer target. Many drug candidates have been developed to inhibit its enzymatic activity. Additionally, PDD00017273 is an effective and s
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 2916, p 2916 (2021)
International Journal of Molecular Sciences
Volume 22
Issue 6
International Journal of Molecular Sciences
Volume 22
Issue 6
5-Fluorouracil (5-FU) is a cornerstone drug used in the treatment of colorectal cancer (CRC). However, the development of resistance to 5-FU and its analogs remain an unsolved problem in CRC treatment. In this study, we investigated the molecular mec