Zobrazeno 1 - 10
of 129
pro vyhledávání: '"Chin-Yo Lin"'
Autor:
Asitha Premaratne, Charles Ho, Shinjini Basu, Ashfia Fatima Khan, Tasneem Bawa-Khalfe, Chin-Yo Lin
Publikováno v:
Biomolecules, Vol 13, Iss 2, p 345 (2023)
Liver X receptors (LXRs) are members of the nuclear receptor family of ligand-dependent transcription factors which regulate the expression of lipid and cholesterol metabolism genes. Moreover, LXRs and their ligands have been shown to inhibit tumor g
Externí odkaz:
https://doaj.org/article/2f8e6b7dfba94a36b1e587382e3d2b8f
Autor:
Fahmi Mesmar, Bingbing Dai, Ahmed Ibrahim, Linnea Hases, Mohammed Hakim Jafferali, Jithesh Jose Augustine, Sebastian DiLorenzo, Ya'an Kang, Yang Zhao, Jing Wang, Michael Kim, Chin‐Yo Lin, Anders Berkenstam, Jason Fleming, Cecilia Williams
Publikováno v:
Cancer Medicine, Vol 8, Iss 18, Pp 7705-7719 (2019)
Abstract Despite advances in cancer therapeutics, pancreatic cancer remains difficult to treat and often develops resistance to chemotherapies. We have evaluated a bioavailable genistein analogue, AXP107‐11 which has completed phase Ib clinical tri
Externí odkaz:
https://doaj.org/article/900afa4941d14028b0d39be55bc5e75d
Autor:
Surendra Chaurasiya, Scott Widmann, Cindy Botero, Chin-Yo Lin, Jan-Åke Gustafsson, Anders M Strom
Publikováno v:
PLoS ONE, Vol 15, Iss 5, p e0226057 (2020)
Estrogen receptor β (ERβ) was first identified in the rodent prostate and is abundantly expressed in human and rodent prostate epithelium, stroma, immune cells and endothelium of the blood vessels. In the prostates of mice with inactivated ERβ, mu
Externí odkaz:
https://doaj.org/article/e2520a8e13524b76a09c7285bc8b6085
Publikováno v:
Viruses, Vol 13, Iss 3, p 433 (2021)
Pyruvate kinase M2 (PKM2) mainly catalyzes glycolysis, but it also exerts non-glycolytic functions in several cancers. While it has been shown to interact with the human papillomavirus 16 (HPV16) E7 oncoprotein, the functional significance of PKM2 in
Externí odkaz:
https://doaj.org/article/ffe2209b0cf2484a813ea31387b934e7
Autor:
Chin-Yo Lin, Erica L. Kleinbrink, Fabien Dachet, Juan Cai, Donghong Ju, Amanda Goldstone, Emily J. Wood, Ka Liu, Hui Jia, Anton-Scott Goustin, Mary A. Kosir, Pattaraporn Thepsuwan, Leonard Lipovich
Publikováno v:
Open Biology, Vol 6, Iss 12 (2016)
Long non-coding RNAs (lncRNAs) are transcripts of a recently discovered class of genes which do not code for proteins. LncRNA genes are approximately as numerous as protein-coding genes in the human genome. However, comparatively little remains known
Externí odkaz:
https://doaj.org/article/f8eafbf3194d4eee91ed0ee523d0d627
Autor:
Nicholes R Candelaria, Ryan Weldon, Selvaraj Muthusamy, Trang Nguyen-Vu, Sridevi Addanki, Paule-Helena Yoffou, Husna Karaboga, Alicia M Blessing, Lakshmi Reddy Bollu, Rajesh C Miranda, Chin-Yo Lin
Publikováno v:
PLoS ONE, Vol 10, Iss 12, p e0145061 (2015)
Hereditary, hormonal, and behavioral factors contribute to the development of breast cancer. Alcohol consumption is a modifiable behavior that is linked to increased breast cancer risks and is associated with the development of hormone-dependent brea
Externí odkaz:
https://doaj.org/article/8937aadc38d44822907f4569ae23030b
Autor:
Emily L.C. Tan, Eng Eong Ooi, Chin-Yo Lin, Hwee Cheng Tan, Ai Ee Ling, Bing Lim, Lawrence W. Stanton
Publikováno v:
Emerging Infectious Diseases, Vol 10, Iss 4, Pp 581-586 (2004)
Severe acute respiratory syndrome (SARS) is an infectious disease caused by a newly identified human coronavirus (SARS-CoV). Currently, no effective drug exists to treat SARS-CoV infection. In this study, we investigated whether a panel of commercial
Externí odkaz:
https://doaj.org/article/e4949f453de247a08982db4d475338dc
Autor:
Nicholes R Candelaria, Sridevi Addanki, Jine Zheng, Trang Nguyen-Vu, Husna Karaboga, Prasenjit Dey, Chiara Gabbi, Lise-Lotte Vedin, Ka Liu, Wanfu Wu, Philip K Jonsson, Jean Z Lin, Fei Su, Lakshmi Reddy Bollu, Sally E Hodges, Amy L McElhany, Mehdi A Issazadeh, William E Fisher, Michael M Ittmann, Knut R Steffensen, Jan-Åke Gustafsson, Chin-Yo Lin
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e106289 (2014)
Pancreatic ductal adenocarcinoma (PDAC) is difficult to detect early and is often resistant to standard chemotherapeutic options, contributing to extremely poor disease outcomes. Members of the nuclear receptor superfamily carry out essential biologi
Externí odkaz:
https://doaj.org/article/4b766a328e044a598a76bfafa68f8a91
Autor:
Chin-Yo Lin, Vinsensius B Vega, Jane S Thomsen, Tao Zhang, Say Li Kong, Min Xie, Kuo Ping Chiu, Leonard Lipovich, Daniel H Barnett, Fabio Stossi, Ailing Yeo, Joshy George, Vladimir A Kuznetsov, Yew Kok Lee, Tze Howe Charn, Nallasivam Palanisamy, Lance D Miller, Edwin Cheung, Benita S Katzenellenbogen, Yijun Ruan, Guillaume Bourque, Chia-Lin Wei, Edison T Liu
Publikováno v:
PLoS Genetics, Vol 3, Iss 6, p e87 (2007)
Using a chromatin immunoprecipitation-paired end diTag cloning and sequencing strategy, we mapped estrogen receptor alpha (ERalpha) binding sites in MCF-7 breast cancer cells. We identified 1,234 high confidence binding clusters of which 94% are proj
Externí odkaz:
https://doaj.org/article/c5d23618fafe47a999d02e29af566afb
