Zobrazeno 1 - 10
of 65
pro vyhledávání: '"Chin-Wen Png"'
Autor:
Si Xian Ho, Jia-Hao Law, Chin-Wen Png, Rudi Alberts, Yongliang Zhang, Justin Jang Hann Chu, Ker-Kan Tan
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Viruses are a key component of the colon microbiome, but the relationship between virome and colorectal cancer (CRC) remains poorly understood. We seek to identify alterations in the viral community that is characteristic of CRC and examine
Externí odkaz:
https://doaj.org/article/6b9f74b63570473cb38e90b1ad873819
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract There is growing interest in the role of gut microbiome in colorectal cancer (CRC), ranging from screening to disease recurrence. Our study aims to identify microbial markers characteristic of CRC and to examine if changes in bacteriome pers
Externí odkaz:
https://doaj.org/article/a755a81ac4c24b7ebb004957961f9403
Autor:
Chin Wen Png, Madhushanee Weerasooriya, Heng Li, Xiaowen Hou, Fiona Yayuan Teo, Shiying Huang, Zheng Ser, Franklin Yau Kok Weng, Malini Rethnam, Gloryn Chia, Radoslaw M. Sobota, Choon Seng Chong, Ker-Kan Tan, Yongliang Zhang
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Notch1 plays various roles in cancer development, and Notch1-induced transactivation is controlled by phosphorylation of its cleaved intracellular domain. However, it is unclear whether there are phosphatases capable of dephosphorylating the
Externí odkaz:
https://doaj.org/article/b22635b1d45947b59755120e6c4cf559
Autor:
Ramya Movva, Nida Murtaza, Rabina Giri, Chin Wen Png, Julie Davies, Saleh Alabbas, Iulia Oancea, Páraic O'Cuiv, Mark Morrison, Jakob Begun, Timothy H. Florin
Publikováno v:
Gastro Hep Advances, Vol 1, Iss 3, Pp 359-374 (2022)
Background and Aims: There is clinical interest in the sustainability or otherwise of prebiotic, microbial, and antibiotic treatments to both prevent and treat inflammatory bowel diseases. This study examined the role of antibiotic manipulation of th
Externí odkaz:
https://doaj.org/article/1c205f339420446d94e162e8111db893
Autor:
Heng Boon Low, Zhen Lim Wong, Bangyuan Wu, Li Ren Kong, Chin Wen Png, Yik-Lam Cho, Chun-Wei Li, Fengchun Xiao, Xuan Xin, Henry Yang, Jia Min Loo, Fiona Yi Xin Lee, Iain Bee Huat Tan, Ramanuj DasGupta, Han-Ming Shen, Herbert Schwarz, Nicholas R. J. Gascoigne, Boon Cher Goh, Xiaohong Xu, Yongliang Zhang
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Chemoresistance is one of the main challenges for cancer therapy success. Here, the authors show that dual-specificity phosphatase 16 (DUSP16) expression is associated with chemoresistance in several types of cancer through impairing mitochondria-ass
Externí odkaz:
https://doaj.org/article/7cd1e1ed821d475f86d18b8927eabe0d
Autor:
Zhen Long Ng, Jiamin Siew, Jia Li, Guanxu Ji, Min Huang, Xiaohua Liao, Sue Yu, Yuanyuan Chew, Chin Wen Png, Yongliang Zhang, Shijun Wen, Henry Yang, Yiting Zhou, Yun Chau Long, Zhi Hong Jiang, Qiang Wu
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Liver cancer is the third most common cause of cancer death in the world. POZ/BTB and AT-hook-containing zinc finger protein 1 (PATZ1/MAZR) is a transcription factor associated with various cancers. However, the role of PATZ1 in cancer progression re
Externí odkaz:
https://doaj.org/article/47a1f535243f4ded815f01c5626b4e05
Autor:
Lei Deng, Lukasz Wojciech, Chin Wen Png, Dorinda Yan Qin Kioh, Yuxiang Gu, Thet Tun Aung, Benoit Malleret, Eric Chun Yong Chan, Guangneng Peng, Yongliang Zhang, Nicholas Robert John Gascoigne, Kevin Shyong Wei Tan
Publikováno v:
Theranostics. 13:1165-1179
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0d3405ac4a74e63e696365d8958b835a
https://doi.org/10.7150/thno.81583
https://doi.org/10.7150/thno.81583
Autor:
Chin Wen Png, Madhushanee Weerasooriya, Xiaowen Hou, Yaxuan Fiona Teo, Ser Zheng, Radoslaw Sobota, Choon Seng Chong, Ker-Kan Tan, Yongliang Zhang
Notch1 plays various roles in cancer development and Notch1-induced transactivation is controlled by phosphorylation of its cleaved intracellular domain. However, if there are phosphatases that are able to dephosphorylate cleaved Notch1 intracellular
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6f181721992b6d310cc288a5b6299a96
https://doi.org/10.21203/rs.3.rs-2931411/v1
https://doi.org/10.21203/rs.3.rs-2931411/v1
Autor:
Lei Deng, Lukasz Wojciech, Chin Wen Png, Yan Qin Dorinda Kioh, Geok Choo Ng, Eric Chun Yong Chan, Yongliang Zhang, Nicholas R. J. Gascoigne, Kevin Shyong Wei Tan
Publikováno v:
npj Biofilms and Microbiomes. 9
Blastocystis is a species complex that exhibits extensive genetic diversity, evidenced by its classification into several genetically distinct subtypes (ST). Although several studies have shown the relationships between a specific subtype and gut mic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::325257f3c7ad3e4ec750c5070a485d6e
https://doi.org/10.1038/s41522-023-00389-1
https://doi.org/10.1038/s41522-023-00389-1
Autor:
Shijia Joy Chua, Wei Jie Jonathan Lee, Chin Wen Png, Yong Liang Zhang, Feng Zhu, Khay Guan Yeoh
Publikováno v:
Theranostics
Background & Aims: Dysbiosis is associated with gastric cancer (GC) development. However, no longitudinal study was carried out to identify key bacteria that could predict for GC progression. Here, we aimed to investigate changes in bacterial metagen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b5be8e26516888a28ee85862c09092d
https://doi.org/10.7150/thno.65302
https://doi.org/10.7150/thno.65302