Výsledky vyhledávání - "Chin-Tarng Lin"

Akademický článek

A novel peptide enhances therapeutic efficacy of liposomal anti-cancer drugs in mice models of human lung cancer.

Autor: De-Kuan Chang, Chin-Tarng Lin, Chien-Hsun Wu, Han-Chung Wu

Publikováno v: PLoS ONE, Vol 4, Iss 1, p e4171 (2009)

Lung cancer is the leading cause of cancer-related mortality worldwide. The lack of tumor specificity remains a major drawback for effective chemotherapies and results in dose-limiting toxicities. However, a ligand-mediated drug delivery system shoul

Externí odkaz: https://doaj.org/article/e0d31cb5e6ac454cbd4d6c8550959fbc

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Data from Peptide-Mediated Targeting to Tumor Blood Vessels of Lung Cancer for Drug Delivery

Autor: Han-Chung Wu, De-Kuan Chang, Szu-Yao Kuo, Chin-Tarng Lin, Tong-Young Lee

Antiangiogenesis therapies for the treatment of cancers hold the promise of high efficacy and low toxicity. In vivo phage display was used to identify peptides specifically targeting tumor blood vessels. The peptide SP5-52 recognized tumor neovascula

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::508297923a9889ad65a0b25fb2820637
https://doi.org/10.1158/0008-5472.c.6496230.v1

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Preclinical verification of the efficacy by targeting peptide-linked liposomal nanoparticles for hepatocellular carcinoma therapy

Autor: Chih-Feng Lin, Chin-Tarng Lin, Ming-Chen Hsu, Cheng-Der Wu, Chung-Wei Lee, Hang-Chung Wu, Jen-Chieh Lee

Publikováno v: Nanobiomedicine, Vol 6 (2019)
Nanobiomedicine

The purpose of this study was to investigate the efficacy of targeting peptides chemotherapy to overcome adverse event in the conventional chemotherapy for human hepatocellular carcinoma. Previously we reported several cancer-targeting peptides that

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::692a30b1e36bf4cf4f0e85164ecba44a
https://doaj.org/article/8aeade6511c74ba8af6da23625fcd5a0

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Liposomal paclitaxel induces fewer hematopoietic and cardiovascular complications than bioequivalent doses of Taxol

Autor: Chin-Tarng Lin, Han-Chung Wu, Yen-Hui Chen, Shih-Ting Huang, Wen-Shan Li, Yi Ping Wang

Publikováno v: International Journal of Oncology

Paclitaxel (PTX) exhibits potent antineoplastic activity against various human malignancies; however, clinical application must overcome the inherent hydrophobicity of this molecule. The commercialized Taxol formulation utilizes Cremophor EL (CrEL)/e

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f78d3fcb247c3676104d33df2db45d6c
https://doi.org/10.3892/ijo.2018.4449

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Abstract 2184: Preclinical verification of the efficacy of targeting peptides linked liposomal nanoparticles for therapy of hepatocellular and nasopharyngeal carcinomas and breast cancer

Autor: Chin-Tarng Lin, Cheng-Der Wu, Jen-Chien Lee, Han-Chung Wu, Chung-Wei Lee, Ming-Chieh Hsu

Publikováno v: Cancer Research. 79:2184-2184

The efficacy of systemic cytotoxic chemotherapy has been widely assessed in patients with advanced hepatocellular carcinoma (HCC). For example, doxorubicin is the most commonly studied chemotherapeutic agent for HCC. However, it has been shown to hav

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::bf57aef0ac291bc26387884be5fa50d4
https://doi.org/10.1158/1538-7445.am2019-2184

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In vitro evaluation of the L-peptide modified magnetic lipid nanoparticles as targeted magnetic resonance imaging contrast agent for the nasopharyngeal cancer

Autor: Chia-Na Min, Chin-Tarng Lin, Han-Chung Wu, Wen-Yuan Hsieh, Yung-Chu Chen

Publikováno v: Journal of Biomaterials Applications. 28:580-594

The purpose of this study was to analyze the encapsulation of superparamagnetic iron oxide nanoparticles (SPION) by the lipid nanoparticle conjugated with the 12-mer peptides (RLLDTNRPLLPY, L-peptide), and the delivery of this complex into living cel

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f66808e22a61921a818f6046f42c5ab
https://doi.org/10.1177/0885328212466685

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