Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Chin K Sung"'
Publikováno v:
Journal of Endocrinology. 198:375-384
Insulin is important in the regulation of muscle metabolism. However, its role in the regulation of muscle long-chain fatty acid (LCFA) metabolism, independent of glucose, is not clear. To determine whether insulin regulates LCFA metabolism independe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::135941c5be3dfa72e258557a2620fdcb
https://doi.org/10.1677/joe-08-0122
https://doi.org/10.1677/joe-08-0122
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 286:G722-G729
Diminished activity of peroxisome proliferator-activated receptor γ (PPARγ) is implicated in activation of hepatic stellate cells (HSC), a critical event in the development of liver fibrosis. In the present study, we investigated PPARγ regulation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb8594346e598c49858a0b50fd5254a2
https://doi.org/10.1152/ajpgi.00411.2003
https://doi.org/10.1152/ajpgi.00411.2003
Autor:
Emma Heart, Chin K. Sung
Publikováno v:
Journal of Cellular Biochemistry. 88:719-731
In insulin-sensitive 3T3-L1 adipocytes, selenium stimulates glucose transport and antilipolysis and these actions of selenium, like insulin actions, are sensitive to wortmanin, an inhibitor of phosphatidylinositol-3-kinase (PI3K). Selenium stimulates
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cac69e59af7c07ff31d616b9650a8f5
https://doi.org/10.1002/jcb.10395
https://doi.org/10.1002/jcb.10395
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism. 282:E170-E176
Sucrose feeding reduces the ability of insulin to suppress glucose production and hepatic gluconeogenesis. The present study examined the effect of a high-sucrose diet on early insulin-signaling steps in the liver. Rats were provided a high-starch (S
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3daf060434cd1ea34fac807d752ffc2
https://doi.org/10.1152/ajpendo.2002.282.1.e170
https://doi.org/10.1152/ajpendo.2002.282.1.e170
Autor:
Woo S Choi, Chin K Sung
Publikováno v:
Biochimica et Biophysica Acta (BBA) - General Subjects. 1475:225-230
In insulin-sensitive L6 myocytes, insulin stimulated glycogen synthesis in a dose-dependent manner and lithium further stimulated glycogen synthesis at all insulin concentrations. Lithium alone at 20 mM stimulated glycogen synthesis to the degree sim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3a6e6741fb43e2e01c9da75460292f5
https://doi.org/10.1016/s0304-4165(00)00068-4
https://doi.org/10.1016/s0304-4165(00)00068-4
Autor:
Vincenzo Pezzino, Riccardo Vigneri, Biancamaria Gliozzo, Giovanni Milazzo, Chin K. Sung, Pierluigi Scalia, Francesco Giorgino, Francesco Frasca, Ira D. Goldfine, Laura Sciacca, Vincenzo Papa
Publikováno v:
Journal of Cellular Biochemistry. 70:268-280
In many human breast cancers and cultured cell lines, insulin receptor expression is elevated, and insulin, via its own insulin receptor, can stimulate cell growth. It has recently been demonstrated that the enzyme phosphatidylinositol-3-kinase (PI3-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c5f20878fa434a0fe850ea1eeeee744
https://doi.org/10.1002/(sici)1097-4644(19980801)70:2<268::aid-jcb12>3.0.co
https://doi.org/10.1002/(sici)1097-4644(19980801)70:2<268::aid-jcb12>3.0.co
Publikováno v:
Endocrinology. 139:2392-2398
The insulin receptor, following insulin stimulation of cells, triggers formation of various signaling complexes. In rat HTC hepatoma cells overexpressing normal human insulin receptors (HTC-IR), p85 regulatory subunit of phosphatidylinositol-3-kinase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5624d45efb0b2eb0f851833c70469c10
https://doi.org/10.1210/endo.139.5.6019
https://doi.org/10.1210/endo.139.5.6019
Publikováno v:
Journal of Cellular Biochemistry. 68:366-377
An elevated content of membrane glycoprotein PC-1 has been observed in cells and tissues of insulin resistant patients. In addition, in vitro overexpression of PC-1 in cultured cells induces insulin resistance associated with diminished insulin recep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::744f0bb3d5dd934781f4dbd98bbc0cfc
https://doi.org/10.1002/(sici)1097-4644(19980301)68:3<366::aid-jcb7>3.0.co
https://doi.org/10.1002/(sici)1097-4644(19980301)68:3<366::aid-jcb7>3.0.co
Publikováno v:
Molecular Endocrinology. 9:435-442
After insulin stimulation of cells, signaling complexes are formed, containing the insulin receptor (IR), insulin receptor substrate-1 (IRS-1), and phosphatidylinositol-3-kinase. To study the nature of these complexes, we employed purified IR, recomb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a86f7fc0a27be954b827c84041460509
https://doi.org/10.1210/mend.9.4.7659087
https://doi.org/10.1210/mend.9.4.7659087
Publikováno v:
Journal of Biological Chemistry. 269:12503-12507
After insulin stimulation of rat HTC hepatoma cells overexpressing normal human insulin receptors (IR), an antiserum to the p85 subunit of phosphatidylinositol-3-kinase (PIK) (alpha-p85) immunoprecipitated three major tyrosine-phosphorylated proteins
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::92785d91f92670c134af7b7fc8819539
https://doi.org/10.1016/s0021-9258(18)99903-5
https://doi.org/10.1016/s0021-9258(18)99903-5